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1.
Cutis ; 97(3): E8-E12, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27023094

RESUMO

Serratia marcescens is an unusual cause of severe skin infection initially described in immunocompromised patients. We report a case of necrotizing cellulitis of the leg caused by S marcescens in a 68-year-old woman with diabetes mellitus and a history of chronic lymphoedema of the leg. We reviewed the literature and found 49 cases of severe skin infections from S marcescens that included 20 cases of necrotizing fasciitis (NF) as well as 29 cases of severe skin infections without NF (non-NF cases). Patients were immunocompromised in 59% to 70% of cases. The mortality rate was high in NF cases (60%) versus non-NF cases (3%). Surgery was required in 95% of NF cases and in 24% of non-NF cases. The other clinical manifestations of S marcescens skin infection reported in the literature included disseminated papular eruptions in patients infected with human immunodeficiency virus with folliculitis on the trunk. Serratia marcescens is naturally resistant to amoxicillin alone and amoxicillin associated with clavulanic acid. Broad-spectrum antibiotics are indicated to treat S marcescens skin infections, and surgery should be promptly considered in cases of severe skin infections if appropriate antibiotic therapy does not lead to rapid improvement.


Assuntos
Celulite (Flegmão)/diagnóstico , Fasciite Necrosante/diagnóstico , Infecções por Serratia/diagnóstico , Serratia marcescens/isolamento & purificação , Abscesso/microbiologia , Abscesso/patologia , Idoso , Antibacterianos/uso terapêutico , Celulite (Flegmão)/microbiologia , Celulite (Flegmão)/patologia , Fasciite Necrosante/microbiologia , Fasciite Necrosante/patologia , Feminino , Humanos , Perna (Membro) , Infecções por Serratia/microbiologia , Infecções por Serratia/patologia
2.
Soins ; (765): 44-6, 2012 May.
Artigo em Francês | MEDLINE | ID: mdl-22730887

RESUMO

In France, eschars concern 250 000 patients every year. The treatment provided depends on the clinical stages. Aside from preventative and curative medical treatments, reconstructive surgery of eschars using flaps offers a functional reconstruction of the affected zone.


Assuntos
Procedimentos Cirúrgicos Dermatológicos , Pele/patologia , Humanos , Necrose , Retalhos Cirúrgicos
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