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Intern Med ; 46(7): 377-81, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17409601

RESUMO

An 80-year-old woman was admitted to our hospital with complaints of jaundice and liver dysfunction. She was found to have a high titer of serum IgG4, positive rheumatoid factor and marked elevation of DUPAN-2 (11,148 U/ml). Computed tomography showed swelling of the pancreas, and endoscopic retrograde cholangiopancreatography revealed diffuse irregular narrowing of the main pancreatic duct, which are typical findings of autoimmune pancreatitis. There was no evidence of malignancy. Administration of 30 mg/day of prednisolone was started. Computed tomography showed significant regression in the size of the pancreas, and the stenosis of the main pancreatic duct was improved on ERCP. The serum level of DUPAN-2 was also markedly decreased after the treatment.


Assuntos
Antígenos de Neoplasias/sangue , Doenças Autoimunes/sangue , Doenças Autoimunes/diagnóstico , Pancreatite/sangue , Pancreatite/diagnóstico , Doença Aguda , Corticosteroides/uso terapêutico , Idoso de 80 Anos ou mais , Doenças Autoimunes/tratamento farmacológico , Biomarcadores/sangue , Colangiopancreatografia Retrógrada Endoscópica/métodos , Diagnóstico Diferencial , Feminino , Humanos , Testes de Função Pancreática , Neoplasias Pancreáticas/diagnóstico , Pancreatite/tratamento farmacológico , Medição de Risco , Índice de Gravidade de Doença , Tomografia Computadorizada por Raios X , Resultado do Tratamento
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