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Br J Radiol ; 75(899): 874-8, 2002 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-12466251

RESUMO

The aim of this study was to investigate the prevalence of renal cortical retention (RCR) of contrast media seen on delayed CT, and nephropathy following transarterial chemoembolisation (TACE) in high-risk patients. The findings of 18 patients with abnormally high serum creatinine levels who underwent TACE were reviewed. Nephropathy was defined as an increase in serum creatinine level of more than 44 micromol l(-1), or more than 25%, on day 1, 3, 7 or 14. RCR was defined as mild (CT value >50) or severe (CT value >100). RCR was seen in 16 cases (89%) and in seven cases (39%) of post-TACE nephropathy. Patients without severe RCR did not develop nephropathy post-TACE, whereas 50% of those with such retention did (p=0.19). Delayed CT appears to have the potential as an early detector of nephropathy post-TACE in high-risk patients.


Assuntos
Quimioembolização Terapêutica/efeitos adversos , Meios de Contraste/farmacocinética , Creatinina/sangue , Córtex Renal/metabolismo , Nefropatias/induzido quimicamente , Adulto , Idoso , Biomarcadores/sangue , Meios de Contraste/efeitos adversos , Feminino , Humanos , Córtex Renal/diagnóstico por imagem , Nefropatias/sangue , Nefropatias/diagnóstico por imagem , Neoplasias Hepáticas/terapia , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X
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