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1.
Artigo em Russo | MEDLINE | ID: mdl-19715204

RESUMO

AIM: To study the influence of Solcotichovac vaccine on formation of neutrophil extracellular traps. MATERIALS AND METHODS: Solcotrichovac vaccine administered in various doses was used in order to assess the formation of neutrophil extracellular traps in peripheral blood of women of childbearing age. RESULTS: Therapeutic dose of Solcotrichovac stimulated the most prominent formation of neutrophil extracellular traps. CONCLUSION: Solcotrichovac vaccine stimulated non-specific arm of mucosal immunity due to formation of neutrophil extracellular traps and it is probable that this mechanism explains the effect of this vaccine.


Assuntos
Vacinas Bacterianas/administração & dosagem , Vacinas Bacterianas/imunologia , Neutrófilos/imunologia , Adulto , Relação Dose-Resposta Imunológica , Feminino , Humanos , Imunidade Inata , Mucosa/imunologia , Neutrófilos/ultraestrutura , Vagina/imunologia
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