RESUMO
We report a case of a man with sarcoidosis and diffuse systemic sclerosis who showed improvement of both diseases after prednisone therapy and remains asymptomatic after three years of follow-up. The association of these two diseases is rare and it is controversial whether this is a chance association or if there is a relationship between the two autoimmune diseases. Despite the poor prognosis and response to therapy of the patients with diffuse systemic sclerosis, our patient had a marked improvement of the disease with prednisone.
Assuntos
Doenças Autoimunes/tratamento farmacológico , Imunossupressores/uso terapêutico , Prednisona/uso terapêutico , Sarcoidose/tratamento farmacológico , Escleroderma Sistêmico/tratamento farmacológico , Doenças Autoimunes/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico , Doença de Raynaud/tratamento farmacológico , Doença de Raynaud/etiologia , Indução de Remissão , Sarcoidose/complicações , Sarcoidose/patologia , Escleroderma Sistêmico/complicações , Escleroderma Sistêmico/patologiaRESUMO
We report a 35-year-old caucasian female with a history of polymorphic light eruption (PLE) who, after the outbreak of pruritic papules following the first sun exposure of the year, developed target lesions in two different bouts, the first on sun-exposed skin and the second on sun-protected sites. A diagnosis of erythema multiforme (EM) developing as a result of PLE was made. As far as we were able to search in the literature, EM occurring in two bouts has not been described previously. We discuss the differential diagnosis.
