1.
Eur J Intern Med
; 90: 114-115, 2021 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34099368
2.
J Infect Dev Ctries
; 8(6): 799-803, 2014 Jun 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24916883
RESUMO
Bleeding complications in dengue may occur irrespective of the presence of plasma leakage. We compared plasma levels of modulators of the endothelial barrier among three dengue groups: bleedings without plasma leakage, dengue hemorrhagic fever, and non-complicated dengue. The aim was to evaluate whether the presence of subtle alterations in microvascular permeability could be detected in bleeding patients. Plasma levels of VEGF-A and its soluble receptors were not associated with the occurrence of bleeding in patients without plasma leakage. These results provide additional rationale for considering bleeding as a complication independent of endothelial barrier breakdown, as proposed by the 2009 WHO classification.