RESUMO
The authors present a patient with locally advanced recurrent pheochromocytoma of the left adrenal gland three years after open adrenalectomy. The patient underwent resection of recurrent tumor of the left adrenal gland, left-sided nephrectomy, splenectomy, resection of pancreatic tail, left dome of the diaphragm and descending colon. Postoperative period was uneventful. The patient was discharged in 12 days after surgery.
Assuntos
Neoplasias das Glândulas Suprarrenais , Feocromocitoma , Humanos , Feocromocitoma/diagnóstico , Feocromocitoma/cirurgia , Recidiva Local de Neoplasia/diagnóstico , Recidiva Local de Neoplasia/cirurgia , Neoplasias das Glândulas Suprarrenais/diagnóstico , Neoplasias das Glândulas Suprarrenais/cirurgia , Neoplasias das Glândulas Suprarrenais/patologia , Adrenalectomia , Glândulas Suprarrenais/patologiaRESUMO
We describe the design and implementation of a stable high-power 1064 nm laser system to generate optical lattices for experiments with ultracold quantum gases. The system is based on a low-noise laser amplified by an array of four heavily modified, high-power fiber amplifiers. The beam intensity is stabilized and controlled with a nonlinear feedback loop. Using real-time monitoring of the resulting optical lattice, we find the stability of the lattice site positions to be well below the lattice spacing over the course of hours. The position of the harmonic trap produced by the Gaussian envelope of the lattice beams is stable to about one lattice spacing and the long-term (six-month) relative root-mean-square stability of the lattice spacing itself is 0.5%.
Assuntos
Adenocarcinoma , Colectomia/efeitos adversos , Colo Sigmoide , Neoplasias do Colo , Recidiva Local de Neoplasia , Adenocarcinoma/patologia , Adenocarcinoma/cirurgia , Colectomia/métodos , Colo Sigmoide/patologia , Colo Sigmoide/cirurgia , Neoplasias do Colo/patologia , Neoplasias do Colo/cirurgia , Feminino , Humanos , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/patologia , Recidiva Local de Neoplasia/cirurgia , Estadiamento de Neoplasias , Reoperação/métodos , Resultado do TratamentoRESUMO
Presented in the article is a clinical case report concerning a 41-year-old female patient with atresia of the first segment of the subclavian artery without combination with other defects and developmental disorders. Described are the process of making the diagnosis and the course of the operative intervention performed, i.e. carotid-subclavian bypass grafting. This is followed by assessing the early postoperative period and immediate therapeutic results.
Assuntos
Artéria Subclávia , Enxerto Vascular/métodos , Malformações Vasculares , Adulto , Angiografia , Feminino , Humanos , Isquemia/etiologia , Isquemia/fisiopatologia , Artéria Subclávia/anormalidades , Artéria Subclávia/diagnóstico por imagem , Artéria Subclávia/cirurgia , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Extremidade Superior/irrigação sanguínea , Extremidade Superior/fisiopatologia , Malformações Vasculares/diagnóstico , Malformações Vasculares/fisiopatologia , Malformações Vasculares/cirurgia , Insuficiência Vertebrobasilar/etiologia , Insuficiência Vertebrobasilar/fisiopatologiaRESUMO
The aim of the study was to reduce perioperative blood loss in patients with giant uterine myoma. As a result of studies have provided evidence that the use of anti fibrinolytic therapy as intravenous infusion of tranexamic acid for 30 minutes before the surgery in a dose of 20 mg/kg followed by infusion of 5 mg/kg per hour for the first postoperative day, helped to reduce perioperative blood loss by 29%. Hemoglobin level was higher by 10% (p < 0,05), blood loss was lower by 29% (p < 0,05), the length of stay in hospital was reduced by 24% (p < 0,05) in patients of the second group on the second postoperative day.
Assuntos
Antifibrinolíticos/uso terapêutico , Leiomioma/cirurgia , Hemorragia Pós-Operatória , Ácido Tranexâmico/uso terapêutico , Miomectomia Uterina/efeitos adversos , Neoplasias Uterinas/cirurgia , Antifibrinolíticos/administração & dosagem , Esquema de Medicação , Feminino , Humanos , Leiomioma/sangue , Pessoa de Meia-Idade , Período Perioperatório , Hemorragia Pós-Operatória/diagnóstico , Hemorragia Pós-Operatória/tratamento farmacológico , Tromboelastografia , Ácido Tranexâmico/administração & dosagem , Neoplasias Uterinas/sangueAssuntos
Carcinoma Medular , Bócio Nodular , Glândula Tireoide , Neoplasias da Glândula Tireoide , Idoso , Carcinoma Medular/complicações , Carcinoma Medular/patologia , Drenagem/métodos , Feminino , Bócio Nodular/complicações , Bócio Nodular/diagnóstico por imagem , Bócio Nodular/fisiopatologia , Bócio Nodular/cirurgia , Humanos , Lesões do Pescoço/complicações , Respiração Artificial/métodos , Ruptura , Índice de Gravidade de Doença , Glândula Tireoide/lesões , Glândula Tireoide/patologia , Neoplasias da Glândula Tireoide/complicações , Neoplasias da Glândula Tireoide/patologia , Resultado do Tratamento , UltrassonografiaRESUMO
AIM: To create adequate orthotopic model of peritoneal carcinomatosis in rats using a transplantable rat tumor M-1 sarcoma, to assess the early tumor response after intraperitoneal photodynamic and/or antiangiogenic therapy for peritoneal carcinomatosis. METHODS: In 14-18 days after intraperitoneal inoculation, eighteen tumor-bearing animals were divided into three groups and undergone intraperitoneal photodynamic therapy and/or antiangiogenic therapy. Assessment of the tumor posttreatment changes was performed using a method of vital staining with Evans blue, MRI-monitoring and morphologic investigation. RESULTS: Percentage of necrosis in disseminated tumors of animals undergone combination therapy significantly higher then after each of the methods alone and achieved 89.46% vs 41.47% after antiangiogenic therapy and 69.73% after photodynamic therapy. Contrast-enhanced MRI showed entirely necrotic tumor nodes in rats undergone the combination therapy. Morphologic study confirmed that tumor response after combination therapy was characterized by maximal spread of necrotic and inflammatory changes in tumor. CONCLUSION: Preliminary results demonstrate enhance of the treatment outcome after combination of antiangiogenic and intraperitoneal photodynamic therapies for peritoneal carcinomatosis in rats.
Assuntos
Inibidores da Angiogênese/administração & dosagem , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Carcinoma/tratamento farmacológico , Neoplasias Peritoneais/tratamento farmacológico , Fotoquimioterapia/métodos , Animais , Carcinoma/patologia , Modelos Animais de Doenças , Transplante de Neoplasias , Neoplasias Peritoneais/patologia , Projetos Piloto , RatosRESUMO
The seven-day DI experiment provided an opportunity to study the effects of decreased proprioceptive, tactile and support afferentation on the vestibular function and visual-manual tracking. Before and after immersion, six subjects participated in videooculographic evaluation of the static torsion otolith-cervicoocular reflex (OCOR) in response to head inclination at 30 degrees in the frontal plane and dynamic vestibular-cervicoocular reactions to head longitudinal rotations at 0.125 Hz. In addition, the hand-eye motor coordination of tracking a jerky (sinusoidal) or smooth (linear) movement of point targets along the horizontal or the vertical was evaluated based on the data of electrooculography and records of manipulations with the joystick during immersion. The computerized test was performed in virtual spectacles dsplaying images of visual stimuli and hand motor acts. Computed parameters included latent reaction time, amplitude, speed and time of eye and hand movements, and gains of optooculomotor reactions and manual tracking as a ratio of eye/hand to visual stimulus speed. Testing was fulfilled before the experiment, in 3 hrs. of immersion, on days 3 and 6 of staying in the bath, in the initial hours after immersion, and on day 3 of recovery. It was shown that removal of support and minimization of proprioceptive afferentation had a profound effect on the ocular tracking rather than hand pursuance of visual stimulus. Accuracy of manual tracking was better comparing with the eye tracking in all the subjects. This was the first time when we observed changes in the peripheral vestibular system in two out of 6 subjects, i.e. inversion of static torsion OCOR and positional nystagmus on the background of converted reflex which did not mar the parameters of oculo-manual tracking.
Assuntos
Movimentos Oculares/fisiologia , Sensação Gravitacional/fisiologia , Imersão/fisiopatologia , Músculos Oculomotores/fisiopatologia , Reflexo Vestíbulo-Ocular/fisiologia , Vestíbulo do Labirinto/fisiopatologia , Adulto , Eletroculografia , Seguimentos , Movimentos da Cabeça/fisiologia , Humanos , Masculino , Músculos Oculomotores/inervação , Membrana dos Otólitos/fisiopatologia , Valores de Referência , Adulto JovemRESUMO
The process of mode conversion, whereby an externally launched electromagnetic wave converts into a shorter wavelength mode(s) in a thermal plasma near a resonance in the index of refraction, is particularly important in a multi-ion species plasma near the ion cyclotron frequency. Using phase contrast imaging techniques (PCI), mode-converted electromagnetic ion cyclotron waves have been detected for the first time in the Alcator C-Mod tokamak near the H-3He ion-ion hybrid resonance region during high power rf heating experiments. The results agree with theoretical predictions.
RESUMO
A comparison of experimental measurements and theoretical studies of the quasicoherent (QC) mode, observed at high densities during enhanced D(alpha) (EDA) H mode in the Alcator C-Mod tokamak, are reported. The QC mode is a high frequency ( approximately 100 kHz) nearly sinusoidal fluctuation in density and magnetic field, localized in the steep density gradient ("pedestal") at the plasma edge, with typical wave numbers k(R) approximately 3-6 cm(-1), k(theta) approximately 1.3 cm(-1) (midplane). It is proposed here that the QC mode is a form of resistive ballooning mode known as the resistive X-point mode, in reasonable agreement with predictions by the BOUT (boundary-plasma turbulence) code.