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1.
Surgeon ; 22(3): 154-157, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38485634

RESUMO

BACKGROUND: The current bleep communication system between nurses and interns on-call in most Irish hospitals has been linked with interruption in patient care, disruption to workflow, inefficiency, increased burden and stress to the on-call health staff. A new electronic system was introduced in a University Hospital to replace and eliminate bleep usage during on-call hours. METHODS: An Intern on-call task electronic template was generated using Microsoft Excel Spreadsheet. This electronic system enabled users to review and respond to requests placed by nursing healthcare staff. This project initially underwent a trial process in three wards for a period of two weeks in June 2023. Interns and nurses were asked to fill a survey before and after introduction of the system. The project was implemented across all wards in August 2023 and a secondary survey was obtained. In addition, the spreadsheets were analysed retrospectively. RESULTS: During the trial, twenty-six interns and twenty nurses were surveyed before and after implementation of the electronic system. Interns satisfaction rate was 73% and stress was reported to be reduced by 65%. Notably, 57% of interns reported a reduction in workload and the number of bleeps was reported to be as <10 by 42%. Nurses reported a decrease in the number of bleeps they needed to send overall by 65% and by 55% for repeated jobs. Workload was reported to be increased by 15% by nurses. However, exactly half of the nurses were unhappy with the new system and stress levels were unchanged. CONCLUSION: This project has shown promising results, efficient and clear communication was noted with an overall positive feedback and satisfaction rate by doctors. However, as evident, from a nursing perspective further work is needed to further progress into a system that can benefit both parties involved.


Assuntos
Internato e Residência , Humanos , Irlanda , Carga de Trabalho , Inquéritos e Questionários , Hospitais Universitários , Satisfação no Emprego , Atitude do Pessoal de Saúde
2.
Ir J Med Sci ; 193(1): 341-343, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37340226

RESUMO

BACKGROUND: Plain film abdomens (PFA) are frequently used in the emergency department to help guide the management of patients presenting with abdominal symptoms. A plain film abdomen contributes minimally to clinical scenarios due to low sensitivity and specificity. Is a PFA useful in the emergency setting or does it serve to further complicate decision making? AIM: We hypothesise that PFAs in the emergency department are over utilised to falsely reassure clinicians and patients alike. METHODS: A search of the National Integrated Medical Imaging System (NIMIS) database in an Irish tertiary referral hospital was conducted. All plain film abdominal radiographs requested by the emergency department between 01/01/2022 and 31/08/2022 were identified. Requests where there was suspicion of foreign body were excluded. A retrospective search of the NIMIS database identified subjects who underwent subsequent imaging. RESULTS: A total of 619 abdominal films were deemed suitable for inclusion. These comprised of 338 male and 282 female subjects. Subjects had an average age of 64 years. Fifty-seven per cent of PFAs detected no abnormality. Forty-two per cent of subjects had subsequent imaging. The plain film findings correlated with further imaging in only 15% of cases. One case of ruptured aortic aneurysm and 11 perforations were detected on computerised tomography, none of these cases were evident on abdominal X-ray. CONCLUSION: Plain film abdomen requests are over utilised in the emergency department. PFAs are not sensitive for detecting acute pathology and should not be used to decide if a patient requires further imaging or a full clinical assessment.


Assuntos
Abdome , Fluorocarbonos , Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Estudos Retrospectivos , Radiografia Abdominal , Tomografia Computadorizada por Raios X , Serviço Hospitalar de Emergência
6.
Eur J Vasc Endovasc Surg ; 66(1): 103-118, 2023 07.
Artigo em Inglês | MEDLINE | ID: mdl-36796674

RESUMO

OBJECTIVE: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is used to temporise non-compressible torso haemorrhage. Recent data have suggested that vascular access complications secondary to REBOA placement are higher than initially anticipated. This updated systematic review and meta-analysis aimed to determine the pooled incidence rate of lower extremity arterial complications after REBOA. DATA SOURCES: PubMed, Scopus, Embase, conference abstract listings, and clinical trial registries. REVIEW METHODS: Studies including more than five adults undergoing emergency REBOA for exsanguinating haemorrhage that reported access site complications were eligible for inclusion. A pooled meta-analysis of vascular complications was performed using the DerSimonian-Laird weights for the random effects model, presented as a Forest plot. Further meta-analyses compared the relative risk of access complications between different sheath sizes, percutaneous access techniques, and indications for REBOA. Risk of bias was assessed using the Methodological Index for Non-Randomised Studies (MINORS) tool. RESULTS: No randomised controlled trials were identified, and the overall study quality was poor. Twenty-eight studies including 887 adults were identified. REBOA was performed for trauma in 713 cases. The pooled proportion rate of vascular access complications was 8.6% (95% confidence interval 4.97 - 12.97), with substantial heterogeneity (I2 = 67.6%). There was no significant difference in the relative risk of access complications between 7 and > 10 F sheaths (p = .54), or between ultrasound guided and landmark guided access (p = .081). However, traumatic haemorrhage was associated with a significantly higher risk of complications compared with non-traumatic haemorrhage (p = .034). CONCLUSION: This updated meta-analysis aimed to be as comprehensive as possible considering the poor quality of source data and high risk of bias. It suggested that lower extremity vascular complications were higher than originally suspected after REBOA. While the technical aspects did not appear to impact the safety profile, a cautious association could be drawn between REBOA use for traumatic haemorrhage and a higher risk of arterial complications.


Assuntos
Oclusão com Balão , Doenças Cardiovasculares , Hemorragia , Hemorragia/terapia , Humanos , Extremidade Inferior/fisiopatologia , Aorta
7.
Ir J Med Sci ; 192(3): 1303-1309, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35969339

RESUMO

BACKGROUND: The current sparsity of surgical trainees' exposure to training in operative trauma surgery is multifactorial. This concern has been addressed in the revised Intercollegiate Surgical Curriculum Programme (ISCP) for general and vascular surgery (2021). In the lead up to its implementation, we aimed to assess both trainee and consultant confidence levels as a surrogate reflection in the core competency operative skills in general emergency trauma surgery, identify individual experience in commonly performed trauma procedures and gauge interest in a career in trauma surgery. METHOD: An online survey was circulated to general surgery and vascular surgery trainees and consultants. Self-reported competencies were assessed using a 1-10 confidence rating scale. Most questions were based on competencies in emergency trauma surgery as set out by the ISCP. RESULTS: Out of 251 surgical trainees and consultants, 119 responded to our survey (47.4% response rate). Less than half (44.1%; n = 52) of respondents had experienced a trauma thoracotomy. Respondents scored 'somewhat' or 'not at all' competent in the majority of competencies assessed. CONCLUSION: Self-reported competencies in operative trauma skills across all subgroups were sub-standard with incremental levels of perceived competence proportional to years of surgical training. Our data supports the necessity of the new curriculum, in addition to modern training pathways with direct exposure to operative trauma surgery involving dedicated trauma centres and networks, and responsibility of training pathways in the provision of training trauma surgery.


Assuntos
Cirurgia Geral , Especialidades Cirúrgicas , Humanos , Consultores , Currículo , Especialidades Cirúrgicas/educação , Educação de Pós-Graduação em Medicina , Competência Clínica , Cirurgia Geral/educação
10.
Aust N Z J Obstet Gynaecol ; 59(2): 201-207, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30357810

RESUMO

BACKGROUND: Surgical packing should not be seen as a 'bail out' for the less skilled obstetrician who is unable to control obstetric haemorrhage using conventional techniques. Rather, this should be considered in cases of coagulopathy or where haemorrhage persists from raw surfaces, venous plexuses and inaccessible areas. MATERIALS AND METHODS: Data from seven women who underwent abdomino-pelvic packing for intractable postpartum bleeding were collected. The primary outcome was success of intra-abdominal packing and secondary outcomes included estimated blood loss, units transfused, length of stay and postoperative complications. RESULTS: All seven women (median age 39 years, interquartile range (IQR) 3.25) had caesarean section deliveries with median estimated blood loss of 5521.4 mL (IQR 4475) and median of 6.9 (IQR 4.75) units transfused. Abdomino-pelvic packing was successful in all cases including in three women who had continued bleeding after peripartum hysterectomy. In the remaining four, bleeding stopped with packing, enabling the uterus to be conserved. The median number of packs inserted was 6.1 (IQR 4.2) and median shock index at time of decision to pack was 0.98 (IQR 0.13). The median pack dwell time was 30.8 h (IQR 24), while median length of stay following removal was 48 h (IQR 2.14). CONCLUSION: Intractable bleeding in these seven cases was successfully controlled by abdomino-pelvic packing, allowing supportive correction of hypothermia, tissue acidosis, coagulopathy and hypovolemia. The technique of packing is an essential skill in managing massive obstetric haemorrhage, in addition to uterine balloon tamponade, compression sutures and peripartum hysterectomy.


Assuntos
Técnicas Hemostáticas , Hemorragia Pós-Parto/terapia , Tampões Cirúrgicos , Adulto , Cesárea , Feminino , Humanos , Histerectomia , Pessoa de Meia-Idade , Gravidez , Estudos Retrospectivos
11.
BMJ Case Rep ; 20182018 Jul 18.
Artigo em Inglês | MEDLINE | ID: mdl-30021728

RESUMO

In patients with critical infracrural disease, autologous saphenous vein grafting offers the best reported conduit patency and limb salvage rates but is only feasible in approximately 30% of patients due to the lack of available or suitable vein. In the absence of a suitable length of available vein, various composite grafting techniques have been explored with the aim to improve graft longevity, maximise native vein use and improve overall clinical outcomes, including limb salvage rates. We report a case of a 66-year-old man with critical limb ischaemia and a history of venous disease, where a complex composite sequential bypass graft combining both native vein and synthetic graft, incorporated into a novel intermediate anastomotic technique in a 'diamond' configuration, offered promising results in limb salvage. This case highlights the key steps and advantages in this novel technique.


Assuntos
Implante de Prótese Vascular/métodos , Salvamento de Membro/métodos , Extremidade Inferior/irrigação sanguínea , Artéria Poplítea/transplante , Idoso , Anastomose Cirúrgica/métodos , Autoenxertos , Humanos , Isquemia/etiologia , Isquemia/cirurgia , Extremidade Inferior/diagnóstico por imagem , Angiografia por Ressonância Magnética , Masculino , Doença Arterial Periférica/complicações , Doença Arterial Periférica/diagnóstico por imagem , Artéria Poplítea/diagnóstico por imagem
12.
Intern Emerg Med ; 13(8): 1257-1263, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29705886

RESUMO

The objectives of the study were to determine whether diagnostic accuracy and reliability by on-call teams is affected by communicating chest radiograph (CXR) images via instant messaging on smartphones in comparison to viewing on a workstation. 12 residents viewed 100 CXR images each with a 24% positive rate for significant or acute findings sent to their phones via a popular instant messaging application and reported their findings if any. After an interval of 42 days they viewed the original DICOM images on personal computers and again reported their findings. There were no statistically significant differences in accuracy, agreement, sensitivity, specificity, positive predictive value or negative predictive value between desktop workstation viewed images and images sent via the mobile application. Media messaging is a useful adjunct for quick second opinions on radiological images, without significant decay in diagnostic accuracy. If technical, ethical and legal issues are addressed, it could be incorporated into practice as a useful adjunct.


Assuntos
Competência Clínica/normas , Telerradiologia/normas , Envio de Mensagens de Texto/normas , Tórax/diagnóstico por imagem , Adulto , Competência Clínica/estatística & dados numéricos , Feminino , Humanos , Masculino , Aplicativos Móveis/normas , Aplicativos Móveis/estatística & dados numéricos , Patologia/métodos , Patologia/estatística & dados numéricos , Radiografia/métodos , Radiografia/normas , Radiografia/estatística & dados numéricos , Reprodutibilidade dos Testes , Telerradiologia/métodos , Telerradiologia/estatística & dados numéricos , Envio de Mensagens de Texto/instrumentação , Envio de Mensagens de Texto/estatística & dados numéricos , Tórax/patologia
13.
Ann Vasc Surg ; 38: 318.e1-318.e6, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-27531084

RESUMO

Aneurysmal degeneration of the superior mesenteric artery (SMA) is a rare clinical finding, estimated to affect <1% of the general population in postmortem studies. Due to the rare prevalence of aneurysms affecting the SMA, there are no clear or definitive published consensus guidelines for its management at presentation, with both surgical and endovascular options described. An aberrant or replaced right hepatic artery (RRHA) is thought to affect 10-15% of the population. The prevalence of both conditions presenting concomitantly is unknown, but undoubtedly even rarer. We describe the successful management of a symptomatic SMA aneurysm with an RRHA emerging from the aneurysmal sac presenting to our vascular unit. This was repaired via an open surgical approach with SMA aneurysmectomy and interposition grafting using reversed vein with preservation of RHA liver perfusion via a novel reconstruction option. This case highlights the challenge that visceral aneurysms pose, especially when simple or orthodox reconstruction options are limited due to rare or unusual anatomy.


Assuntos
Aneurisma/complicações , Artéria Hepática/anormalidades , Artéria Mesentérica Superior , Malformações Vasculares/complicações , Anastomose Cirúrgica , Aneurisma/diagnóstico por imagem , Aneurisma/cirurgia , Angiografia por Tomografia Computadorizada , Artéria Hepática/diagnóstico por imagem , Artéria Hepática/cirurgia , Humanos , Masculino , Artéria Mesentérica Superior/diagnóstico por imagem , Artéria Mesentérica Superior/cirurgia , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica , Veia Safena/transplante , Resultado do Tratamento , Enxerto Vascular/métodos , Malformações Vasculares/diagnóstico por imagem , Malformações Vasculares/cirurgia
14.
Trauma Mon ; 21(1): e20421, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27218049

RESUMO

INTRODUCTION: Traumatic diaphragmatic hernia (TDH) develops infrequently following a traumatic diaphragmatic rupture (TDR). As TDR is frequently missed due to lack of sensitive and specific imaging modalities, a high index of suspicion for such injuries is essential, whether immediately posttraumatic, or even decades after the trauma. We describe a rare case of recurrence in a laparoscopically repaired TDH and review the current literature on the same. CASE PRESENTATION: A 23-year-old male with a history of primary laparoscopic repair of left-sided TDR two years ago presented with symptoms of acute large bowel obstruction. His chest X-ray showed a left-sided pleural effusion and a loop of the bowel in the left hemithorax, but no signs of free gas. An abdominal X-ray (AXR) demonstrated massively dilated large bowel with distension of the small bowel. At laparotomy, the obstructing lesion consisted of the large bowel with omentum herniated through the left hemidiaphragm, consistent with a left recurrent/chronic diaphragmatic hernia. The diaphragmatic defect was repaired with interrupted nylon. The patient made an uneventful recovery. CONCLUSIONS: Recurrence after repair of TDH is a less reported condition (with only two published articles) and little is known regarding the factors responsible for this. Laparoscopy is an excellent diagnostic tool, but currently management is probably best performed via an open technique using heavy non-absorbable suture material to prevent recurrence. Long term follow up of these patients should also be considered.

15.
Ann Vasc Surg ; 35: 203.e5-203.e10, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27238997

RESUMO

Mycotic aneurysmal disease of the extracranial carotid arteries (ECA) is a rare entity associated with a high morbidity, including rupture, hemorrhage, airway obstruction, and stroke. Surgical management is challenging due to difficult dissection through infected or inflamed tissue. This report highlights a case of ECA-aneurysm infection presenting with stroke and an occluded internal carotid artery, likely due to microbial arteritis on a background of osteomyelitis. Operative intervention was performed to definitively treat the infection and prevent the potential associated complications. In this case, the incident vessel was 100% occluded at presentation, allowing vessel ligation and resection without carotid complex reconstruction.


Assuntos
Aneurisma Infectado/cirurgia , Implante de Prótese Vascular , Doenças das Artérias Carótidas/cirurgia , Artéria Carótida Interna/cirurgia , Procedimentos de Cirurgia Plástica , Infecções Estafilocócicas/cirurgia , Aneurisma Infectado/diagnóstico por imagem , Aneurisma Infectado/microbiologia , Antibacterianos/administração & dosagem , Prótese Vascular , Implante de Prótese Vascular/instrumentação , Doenças das Artérias Carótidas/diagnóstico por imagem , Doenças das Artérias Carótidas/microbiologia , Artéria Carótida Interna/diagnóstico por imagem , Artéria Carótida Interna/microbiologia , Angiografia Cerebral/métodos , Angiografia por Tomografia Computadorizada , Humanos , Ligadura , Angiografia por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica/instrumentação , Infecções Estafilocócicas/diagnóstico por imagem , Infecções Estafilocócicas/microbiologia , Irrigação Terapêutica , Resultado do Tratamento
16.
J Vasc Surg ; 63(4): 1116-20, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27016861

RESUMO

Composite sequential bypass grafting is an effective alternative in the treatment of peripheral vascular disease when autologous vein is limited. We describe a modified technique for composite sequential bypass grafting anastomosis using a combination of synthetic graft with native vein connected via a common intermediate anastomotic junction, which also benefits from having additional outflow at the native, noncontiguous arteriotomy in a diamond configuration. This technique was piloted on six patients to treat critical limb ischemia when no other revascularization options were deemed suitable. Limb salvage with resolution of symptoms was achieved in all six patients at the 6-month follow-up. The diamond anastomosis is a promising method to maximize limb salvage using a unique composite sequential bypass configuration when native vein is limited.


Assuntos
Implante de Prótese Vascular/métodos , Isquemia/cirurgia , Extremidade Inferior/irrigação sanguínea , Veia Safena/transplante , Idoso , Anastomose Cirúrgica , Prótese Vascular , Implante de Prótese Vascular/instrumentação , Estado Terminal , Feminino , Artéria Femoral/cirurgia , Humanos , Isquemia/diagnóstico , Isquemia/fisiopatologia , Salvamento de Membro , Masculino , Pessoa de Meia-Idade , Politetrafluoretileno , Desenho de Prótese , Recuperação de Função Fisiológica , Fluxo Sanguíneo Regional , Fatores de Tempo , Resultado do Tratamento
17.
BMJ Case Rep ; 20152015 Nov 27.
Artigo em Inglês | MEDLINE | ID: mdl-26621867

RESUMO

The newer approach to management of penetrating neck injuries (PNI) involves the No Zone approach: comprehensive physical examination combined with CT angiography for triage to effectively identify or exclude vascular and aerodigestive injury. This approach, however, has a low negative exploration rate; there is risk of missing occult injuries especially Zone I and III PNI. We report a case of a patient with PNI to Zone I of the neck who was haemodynamically stable at presentation; CT scan revealed complete occlusion of the common carotid artery. Immediate surgical exploration revealed an occult hypopharyngeal injury in addition to the arterial trauma, which was missed on the CT scan. Hence the No Zone approach needs cautious clinical application, especially in Zone I injuries.


Assuntos
Lesões das Artérias Carótidas/diagnóstico por imagem , Artéria Carótida Primitiva/diagnóstico por imagem , Hipofaringe/lesões , Lesões do Pescoço/diagnóstico por imagem , Triagem/métodos , Ferimentos Penetrantes/diagnóstico por imagem , Angiografia , Arteriopatias Oclusivas/diagnóstico por imagem , Arteriopatias Oclusivas/etiologia , Arteriopatias Oclusivas/cirurgia , Lesões das Artérias Carótidas/cirurgia , Artéria Carótida Primitiva/cirurgia , Hematoma/diagnóstico por imagem , Hematoma/etiologia , Humanos , Hipofaringe/diagnóstico por imagem , Hipofaringe/cirurgia , Masculino , Pessoa de Meia-Idade , Lesões do Pescoço/cirurgia , Trombose/diagnóstico por imagem , Trombose/etiologia , Trombose/cirurgia , Tomografia Computadorizada por Raios X , Ferimentos Penetrantes/cirurgia
18.
Trials ; 16: 185, 2015 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-25903752

RESUMO

BACKGROUND: Patients undergoing vascular surgery procedures constitute a 'high-risk' group. Fatal and disabling perioperative complications are common. Complications arise via multiple aetiological pathways. This mechanistic redundancy limits techniques to reduce complications that target individual mechanisms, for example, anti-platelet agents. Remote ischaemic preconditioning (RIPC) induces a protective phenotype in at-risk tissue, conferring protection against ischaemia-reperfusion injury regardless of the trigger. RIPC is induced by repeated periods of upper limb ischaemia-reperfusion produced using a blood pressure cuff. RIPC confers some protection against cardiac and renal injury during major vascular surgery in proof-of-concept trials. Similar trials suggest benefit during cardiac surgery. Several uncertainties remain in advance of a full-scale trial to evaluate clinical efficacy. We propose a feasibility trial to fully evaluate arm-induced RIPC's ability to confer protection in major vascular surgery, assess the incidence of a proposed composite primary efficacy endpoint and evaluate the intervention's acceptability to patients and staff. METHODS/DESIGN: Four hundred major vascular surgery patients in five Irish vascular centres will be randomised (stratified for centre and procedure) to undergo RIPC or not immediately before surgery. RIPC will be induced using a blood pressure cuff with four cycles of 5 minutes of ischaemia followed by 5 minutes of reperfusion immediately before the start of operations. There is no sham intervention. Participants will undergo serum troponin measurements pre-operatively and 1, 2, and 3 days post-operatively. Participants will undergo 12-lead electrocardiograms pre-operatively and on the second post-operative day. Predefined complications within one year of surgery will be recorded. Patient and staff experiences will be explored using qualitative techniques. The primary outcome measure is the proportion of patients who develop elevated serum troponin levels in the first 3 days post-operatively. Secondary outcome measures include length of hospital and critical care stay, unplanned critical care admissions, death, myocardial infarction, stroke, mesenteric ischaemia and need for renal replacement therapy (within 30 days of surgery). DISCUSSION: RIPC is novel intervention with the potential to significantly improve perioperative outcomes. This trial will provide the first evaluation of RIPC's ability to reduce adverse clinical events following major vascular surgery. TRIAL REGISTRATION: www.clinicaltrials.gov NCT02097186 Date Registered: 24 March 2014.


Assuntos
Injúria Renal Aguda/prevenção & controle , Precondicionamento Isquêmico/métodos , Traumatismo por Reperfusão Miocárdica/prevenção & controle , Extremidade Superior/irrigação sanguínea , Procedimentos Cirúrgicos Vasculares/efeitos adversos , Injúria Renal Aguda/sangue , Injúria Renal Aguda/diagnóstico , Injúria Renal Aguda/etiologia , Injúria Renal Aguda/mortalidade , Biomarcadores/sangue , Protocolos Clínicos , Eletrocardiografia , Estudos de Viabilidade , Humanos , Irlanda , Precondicionamento Isquêmico/efeitos adversos , Precondicionamento Isquêmico/mortalidade , Traumatismo por Reperfusão Miocárdica/sangue , Traumatismo por Reperfusão Miocárdica/diagnóstico , Traumatismo por Reperfusão Miocárdica/etiologia , Traumatismo por Reperfusão Miocárdica/mortalidade , Fluxo Sanguíneo Regional , Projetos de Pesquisa , Medição de Risco , Fatores de Risco , Fatores de Tempo , Resultado do Tratamento , Troponina I/sangue , Procedimentos Cirúrgicos Vasculares/mortalidade
19.
J Surg Res ; 180(2): 232-7, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22683082

RESUMO

BACKGROUND: In the critically ill, mineralocorticoid deficiency (MD) is associated with greater disease severity, the development of acute renal insufficiency, and increased mortality. We hypothesized that severely injured trauma patients presenting with hemorrhagic shock would demonstrate a high degree of MD. We also hypothesized that MD in these patients would be associated with increased length of stay, hypotension, fluid requirements, and acute kidney injury (AKI). MATERIALS AND METHODS: Thirty-two trauma patients in hemorrhagic shock on admission to the trauma bay (SBP <90 mm Hg × 2) were enrolled. Blood samples were obtained on ICU admission and 8, 16, 24, and 48 hours later. Plasma aldosterone (PA) and renin (PR) were assayed by radioimmunoassay. MD was defined as a ratio of PA/PR ≤2. Demographic data, injury severity score, ICU and hospital length of stay, fluid requirements, mean arterial pressure, serum sodium, hypotension, and risk for AKI were compared for patients with and without MD. RESULTS: At ICU admission, 48% of patients met criteria for MD. Patients with MD were significantly more likely to experience hypotension (MAP ≤60 mm Hg) during the study period. MD patients required significantly more units of blood in 48 h than non-MD patients (13 [7-22] versus 5 [2-7], P = 0.015) and had increased crystalloid requirements (18L [14-23] versus 9L [6-10], P < 0.001). MD patients were at higher risk for AKI according to RIFLE and AKIN criteria. CONCLUSIONS: MD is a common entity in trauma patients presenting in hemorrhagic shock. Patients with MD required a more aggressive resuscitative effort, were more likely to experience hypotension, and had a higher risk of AKI than non-MD patients. Future studies are needed to fully understand the impact of MD following trauma and the potential role for hormonal replacement therapy.


Assuntos
Mineralocorticoides/deficiência , Choque Hemorrágico/metabolismo , Injúria Renal Aguda/etiologia , Adulto , Soluções Cristaloides , Feminino , Humanos , Hipotensão/etiologia , Soluções Isotônicas , Masculino , Pessoa de Meia-Idade , Ferimentos e Lesões/metabolismo
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