RESUMO
OBJECTIVE: Previous studies have shown a decrease in serum magnesium (Mg) concentration when continuous ambulatory peritoneal dialysis (CAPD) patients previously maintained on a 1.0-1.2 mEq/L Mg peritoneal dialysis solution (PDS) were dialyzed with a 0.5 mEq/L Mg PDS. However, the prevalence of hypomagnesemia in CAPD patients dialyzed with low-Mg PDS is unknown. DESIGN: A retrospective study to determine the prevalence of hypomagnesemia and the factors associated with its occurrence in CAPD patients dialyzed using a 0.5 mEq/L Mg PDS. SETTING: A CAPD unit in a large Veterans Affairs Hospital. PATIENTS: All our CAPD patients (33) enrolled over a 52-month period. RESULTS: All patients had serum magnesium levels higher than 1.25 mEq/L prior to use of low-Mg PDS. Hypomagnesemia (serum Mg < 1.25 mEq/L) developed in 21/33 patients (64%) when a 0.5 mEq/L Mg PDS was employed. Hypomagnesemia developed a mean of 8.2 months after beginning treatments. The duration of dialysis and the number of episodes of peritonitis did not differ between patients with and those without hypomagnesemia. Serum albumin levels were significantly lower in patients with hypomagnesemia (2.5 +/- 0.12 g/dL vs 3.2 +/- 0.12, p < 0.01). Magnesium supplements were given to 13 patients; following this therapy, serum magnesium values became normal. CONCLUSIONS: CAPD patients dialyzed with a 0.5 mEq/L Mg PDS may develop a considerable fall in serum magnesium level and may require magnesium supplements in order to restore normal serum values.
Assuntos
Soluções para Diálise/química , Deficiência de Magnésio/etiologia , Magnésio/sangue , Diálise Peritoneal Ambulatorial Contínua , Feminino , Humanos , Falência Renal Crônica/sangue , Falência Renal Crônica/terapia , Magnésio/administração & dosagem , Deficiência de Magnésio/sangue , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Albumina Sérica/análise , Fatores de TempoRESUMO
Continuous ambulatory peritoneal dialysis was successfully carried out in 6 end-stage renal failure patients using self-made, ultrafiltration-sterilized dialysis solutions. A Y-set was used to deliver the above solutions to sterile plastic bags.
Assuntos
Falência Renal Crônica/terapia , Lactatos/normas , Diálise Peritoneal Ambulatorial Contínua , Esterilização/normas , Biomarcadores/sangue , Análise Química do Sangue , Feminino , Hematócrito , Humanos , Lactatos/química , Ácido Láctico , Masculino , Pessoa de Meia-Idade , Soluções , UltrafiltraçãoRESUMO
Peritoneal dialysis was performed on 7 end-stage renal failure patients using an I-lactate-containing solution sterilized by ultrafiltration through polyamide filters. The patients tolerated the procedure well while their metabolic acidosis and azotemia improved.
Assuntos
Soluções para Diálise , Falência Renal Crônica/terapia , Lactatos , Diálise Peritoneal , Humanos , Ácido Láctico , Esterilização , UltrafiltraçãoRESUMO
We performed acute peritoneal dialysis on eight end-stage renal disease patients using a bicarbonate-containing solution sterilized by ultrafiltration through polyamide filters. The patients tolerated the procedure well; their azotemia and metabolic acidosis improved.
Assuntos
Bicarbonatos , Soluções para Diálise , Diálise Peritoneal/métodos , Esterilização/métodos , Ultrafiltração , Humanos , Falência Renal Crônica/terapia , Masculino , Filtros Microporos , Pessoa de Meia-Idade , NylonsRESUMO
Peritoneal sclerosis occurred in two patients treated by continuous ambulatory peritoneal dialysis (CAPD) using only lactate-buffered dialysate. Both patients had recurrent peritonitis and the second patient had multiple, minor abdominal operations. Patients receiving lactate-buffered CAPD are not immune from peritoneal sclerosis. Recurrent peritonitis and repeated abdominal surgery might be important causative factors.