RESUMO
OBJECTIVE: To test the hypothesis that cognitive impairment increases mortality independent of airflow obstruction. MATERIALS AND METHODS: In 1988-1994 the Third National Health and Nutrition Examination Survey (NHANES III) measured forced expiratory volume in the first second (FEV1) and the forced vital capacity (FVC) and selected items on cognitive function with mortality follow-up. For this survival analysis 4365 persons aged 60 and over with complete data formed the analytic sample. RESULTS: The FEV1/FVC less than the lower limit of predicted ratio (LLP) defined airflow obstruction and Composite Cognitive Function Score (CCF) ≤4, cognitive impairment. The percentage who died during follow up was 67% among those with neither FEV1/FVC < LLP nor CCF ≤4, 82% with FEV1/FVC < LLP only, 85% with CCF score ≤4 only and 93% with both FEV1/FVC LLP and CCF score ≤4 (P < .001). Weighted Cox proportional hazards regression revealed an increased hazard ratio (HR) in persons with FEV1/FVC Assuntos
Obstrução das Vias Respiratórias/mortalidade
, Cognição/fisiologia
, Previsões
, Pulmão/fisiopatologia
, Inquéritos Nutricionais
, Idoso
, Obstrução das Vias Respiratórias/diagnóstico
, Obstrução das Vias Respiratórias/fisiopatologia
, Feminino
, Seguimentos
, Volume Expiratório Forçado/fisiologia
, Humanos
, Pulmão/diagnóstico por imagem
, Masculino
, Pessoa de Meia-Idade
, Estudos Retrospectivos
, Espirometria
, Taxa de Sobrevida/tendências
, Estados Unidos/epidemiologia
, Capacidade Vital