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2.
J Assoc Physicians India ; 68(12): 58-60, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33247644

RESUMO

BACKGROUND AND AIM: Coronavirus disease 2019 (COVID 2019) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may cause multisystem dysfunction. We studied pancreatic injury (serum amylase and serum lipase levels) in COVID-19 patients. METHODS: A retrospective study involving 42 COVID-19 patients (diagnosed by real-time PCR) admitted to a tertiary care hospital was conducted. Serum amylase and serum lipase levels were analysed in relation to severity of COVID-19 and mortality. RESULTS: Mean age of patients was 50 ± 16 years, with male to female ratio of 3.7:1. Serum amylase was elevated in 14 patients (33%). Serum lipase was elevated in 7 out of 29 patients (24.1%). Mortality was seen in 18 patients (42.8%). Serum amylase or lipase did not correlate with severity of COVID-19 or its mortality. However, both patients who had high lipase (>3times) died. CONCLUSION: The prevalence of hyperamylasemia in patients of COVID-19 was 33%, while that of elevated lipase was 24.1%. Pancreatic injury failed to show any statistically significant relation to severity or outcome of COVID-19.


Assuntos
Infecções por Coronavirus , Pâncreas , Pancreatopatias , Pandemias , Pneumonia Viral , Adulto , Idoso , Betacoronavirus , COVID-19 , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pancreatopatias/virologia , Estudos Retrospectivos , SARS-CoV-2
3.
J Assoc Physicians India ; 64(11): 32-37, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-27805331

RESUMO

OBJECTIVE: Primary objective of this study was to access utility of exercise treadmill test in type-2 diabetes mellitus patients for detecting silent myocardial ischaemia and associated risk factors. METHODS: 75 DM-2 cases were enrolled in study of any age attending medical OPD. All cases were gone through detailed history and TMT procedure. RESULTS: There is higher prevalence of SMI in DM-2 patients. TMT positivity for inducible ischaemia in DM-2 patients were associated with increasing age, male sex, higher BMI, hypertension, smoking, alcoholism, microalbuminuria, macroalbuminuria and dyslipidemia. Duration of diabetes increases the development of CAD in diabetic patients. TMT is a safe procedure with no complication. CONCLUSIONS: For detection of silent myocardial ischaemia in diabetic patients TMT has a significant role. Prevalence of silent myocardial ischaemia in DM-2 patients is 37.3%. There is significant correlation between risk factors of CVD and evidence of ischaemia on TMT in diabetic patients. Duration of diabetic state has a strong correlation for inducible ischaemia on TMT. It may be a safer, cheaper, reliable and easily available non-invasive screening tool for earlier detection of CAD in diabetic patients.


Assuntos
Diabetes Mellitus Tipo 2/complicações , Angiopatias Diabéticas/diagnóstico , Teste de Esforço , Isquemia Miocárdica/diagnóstico , Isquemia Miocárdica/etiologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos
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