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1.
Laryngorhinootologie ; 92(8): 515-22, 2013 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-23900923

RESUMO

Hypersalivation describes a relatively excessive salivary flow, which wets the patient himself and his surroundings. It may result because of insufficient oro-motor function, dysphagia, decreased central control and coordination. This reduces social interaction chances and burdens daily care. Multidisciplinary diagnostic and treatment evaluation is recommended already at early stage and focus on dysphagia, and saliva aspiration. Therefore, a multidisciplinary S2k guideline was developed. Diagnostic tools such as fiberoptic endoscopic evaluation of swallowing and videofluoroscopic swallowing studies generate important data on therapy selection and control. Especially traumatic and oncologic cases profit from swallowing therapy programmes in order to activate compensation mechanisms. In children with hypotonic oral muscles, oralstimulation plates can induce a relevant symptom release because of the improved lip closure. In acute hypersalivation, the pharmacologic treatment with glycopyrrolate and scopolamine in various applications is useful but its value in long-term usage critical. The injection of botulinum toxin into the salivary glands has shown safe and effective results with long lasting saliva reduction. Surgical treatment should be reserved for isolated cases. External radiation is judged as ultima ratio. Therapy effects and symptom severity has to be followed, especially in neurodegenerative cases. The resulting xerostomia should be critically evaluated by the responsible physician regarding oral and dental hygiene.


Assuntos
Sialorreia/etiologia , Sialorreia/terapia , Adulto , Terapia Comportamental , Toxinas Botulínicas Tipo A/efeitos adversos , Toxinas Botulínicas Tipo A/uso terapêutico , Criança , Terapia Combinada , Comportamento Cooperativo , Transtornos de Deglutição/diagnóstico , Transtornos de Deglutição/etiologia , Transtornos de Deglutição/terapia , Medicina Baseada em Evidências , Terapia por Exercício , Alemanha , Glicopirrolato/efeitos adversos , Glicopirrolato/uso terapêutico , Humanos , Comunicação Interdisciplinar , Ortodontia , Pneumonia Aspirativa/diagnóstico , Pneumonia Aspirativa/etiologia , Pneumonia Aspirativa/prevenção & controle , Escopolamina/efeitos adversos , Escopolamina/uso terapêutico , Sialorreia/diagnóstico
2.
Nervenarzt ; 74(4): 370-5, 2003 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-12707708

RESUMO

The risk of aberrant sexual behaviour such as hypersexuality, exhibitionism, or pederasty may be underestimated in Parkinson's disease and its therapy with high-dosage L-dopa or dopamine agonists. We describe two legal cases which are representative of the forensic assessment of these side effects. The first case brought to court was a 45-year-old man suffering for 20 years from Parkinson's disease who developed hypersexuality and exhibitionism under high-dose therapy with ropinirol. The second patient, a 57-year-old man with an 11-year history of Parkinson's disease, developed increased libido and pederasty under therapy with L-dopa and bromocriptine. We discuss the present literature concerning hypersexuality and sexually deviant behaviour in Parkinson's disease and dopaminergic therapy in the German legal context. Doctors treating Parkinson patients should be aware of increased sexual impulses or reduced behavioural control and ask specifically about them during anamnesis, and counteractive therapeutic strategies should be considered to prevent the occurrence of illegal sexually aberrant behavioural disorders.


Assuntos
Antiparkinsonianos/efeitos adversos , Prova Pericial/legislação & jurisprudência , Doença de Parkinson/tratamento farmacológico , Delitos Sexuais/legislação & jurisprudência , Antiparkinsonianos/uso terapêutico , Conscientização/efeitos dos fármacos , Bromocriptina/efeitos adversos , Bromocriptina/uso terapêutico , Relação Dose-Resposta a Droga , Quimioterapia Combinada , Exibicionismo/induzido quimicamente , Humanos , Comportamento Impulsivo/induzido quimicamente , Indóis/efeitos adversos , Indóis/uso terapêutico , Levodopa/efeitos adversos , Levodopa/uso terapêutico , Libido/efeitos dos fármacos , Masculino , Pessoa de Meia-Idade , Pedofilia/induzido quimicamente
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