RESUMO
A cross sectional observation study was carried out in primary school children of slum dwelling area of Kathmandu Valley which included 454 students. The aim of study was to find out morbidity in habit disorders in age group of 6-10 years so that early detection will be helpful to correct them to prevent it from further personality maladjustment. There was no statistical difference in gender wise habit disorders. The morbidity is due to multiple factors of physico- social environment. However severity of disease is not more here in this area.
Assuntos
Transtornos do Comportamento Infantil/epidemiologia , Áreas de Pobreza , Criança , Estudos Transversais , Feminino , Humanos , Masculino , Nepal/epidemiologiaRESUMO
The effects of oral treatment with coenzyme Q10 (120 mg/d) were compared for 28 days in 73 (intervention group A) and 71 (placebo group B) patients with acute myocardial infarction (AMI). After treatment, angina pectoris (9.5 vs. 28.1), total arrhythmias (9.5% vs. 25.3%), and poor left ventricular function (8.2% vs. 22.5%) were significantly (P < 0.05) reduced in the coenzyme Q group than placebo group. Total cardiac events, including cardiac deaths and nonfatal infarction, were also significantly reduced in the coenzyme Q10 group compared with the placebo group (15.0% vs. 30.9%, P < 0.02). The extent of cardiac disease, elevation in cardiac enzymes, and oxidative stress at entry to the study were comparable between the two groups. Lipid peroxides, diene conjugates, and malondialdehyde, which are indicators of oxidative stress, showed a greater reduction in the treatment group than in the placebo group. The antioxidants vitamin A, E, and C and beta-carotene, which were lower initially after AMI, increased more in the coenzyme Q10 group than in the placebo group. These findings suggest that coenzyme Q10 can provide rapid protective effects in patients with AMI if administered within 3 days of the onset of symptoms. More studies in a larger number of patients and long-term follow-up are needed to confirm our results.
Assuntos
Antioxidantes/uso terapêutico , Infarto do Miocárdio/tratamento farmacológico , Ubiquinona/análogos & derivados , Angina Pectoris/tratamento farmacológico , Arritmias Cardíacas/tratamento farmacológico , Coenzimas , Método Duplo-Cego , Ventrículos do Coração/efeitos dos fármacos , Humanos , Masculino , Infarto do Miocárdio/mortalidade , Infarto do Miocárdio/prevenção & controle , Miocárdio/enzimologia , Estresse Oxidativo/efeitos dos fármacos , Placebos , Fatores de Tempo , Ubiquinona/uso terapêuticoRESUMO
PIP: The authors analyze the biological factors affecting infant mortality in Gorakhpur, a district in eastern Uttar Pradesh, India. The data concern 162 families living in rural, semi-urban, and urban areas and were collected in 1984. The factors considered include age of mother, age and sex of infants, family type, birth spacing, birth order, and birth weight.^ieng