Changes in Electroencephalography Alpha Associated With Childhood Neglect and Adolescent Alcohol Use.

The present pilot study is interested in the relationship between childhood neglect, brain function, and alcohol use in adolescence. The goal is to guide future prevention and intervention efforts related to alcohol use following childhood neglect. This pilot study comprised 53 adolescents (12-14 years at baseline) recruited from the Department of Social Services (DSS). Self- and DSS-reported neglect, electroencephalography (EEG) alpha power, and alcohol use behaviors were measured over 1 year. Higher DSS neglect severity in year 1 was related to lower self-efficacy to alcohol use temptation in year 2. Lower EEG alpha power in the parietal region in year 1 was linked to lower self-efficacy to the temptation of alcohol use in year 2. This pilot project has value for using tools, such as EEG, in child maltreatment and alcohol use studies, including with underrepresented adolescents, to better understand brain-related mechanisms in home-based research.

Alpha EEG asymmetry, childhood maltreatment, and problem behaviors: A pilot home-based study.

BACKGROUND: Child maltreatment, trauma symptoms, and alpha electroencephalography (EEG) asymmetry have been linked to problem behaviors and alcohol use disorders. OBJECTIVE: The goal of this pilot study was to clarify the role of alpha EEG asymmetry in the relation of maltreatment and problem behaviors. It was hypothesized that adolescents with more maltreatment, trauma symptoms, and right alpha EEG asymmetry would have more problem behaviors and alcohol use. It was also hypothesized that alpha EEG asymmetry would moderate the association between maltreatment/trauma symptoms and problem behaviors. PARTICIPANTS AND SETTING: Participants were 52 adolescents aged 12-14 years. Resting-state alpha EEG asymmetry was measured in this home-based study as a potential moderator in the association of child maltreatment and trauma symptoms to problem behaviors including alcohol use. RESULTS: Child maltreatment reports and trauma symptoms were significantly associated with problem behaviors (ß = 0.259, p = 0.037 and ß = 0.594, p < 0.001, respectively). Trauma symptoms were associated with alcohol-use (Incidence Rate Ratio = 1.048, p = 0.032). Right alpha EEG asymmetry moderated the positive association of trauma symptoms and problem behaviors (ß = -0.383, p = 0.024). However, this was not the case for left alpha EEG asymmetry. CONCLUSIONS: Neural correlates associated with individuals' affective-behavioral profiles may play a role in the susceptibility for problem behaviors among adolescents exposed to higher levels of childhood trauma. This could be useful in developing targeted assessments and interventions to prevent or treat these problems in adolescents.