Resultados de un programa educativo para adultos con asma / Results of an educational program for adults with asthma

Antecedentes: el asma es un problema mundial de salud. La educación del paciente asmático se ha propuesto como una alternativa para disminuir la mortalidad causada por este padecimiento. Objetivo: demostrar que los programas educativos para pacientes asmáticos ayudan a reducir la gravedad de la enfermedad, el número de crisis y de hospitalizaciones, y fomentan un mayor apego terapéutico. Material y método: participaron 80 pacientes con asma, que se dividieron en dos grupos; el primero recibió el curso educativo y el segundo no. A todos los sujetos se les dio tratamiento de acuerdo con las guías internacionales que incluyen consulta mensual, flujómetro, cámara espaciadora y diario de síntomas; se les realizó una evaluación inicial y una final sobre conocimiento de la enfermedad. El curso consistió en un taller que abarcó el manejo de las crisis, el uso de medicamentos inhalados, la flujometría y las técnicas de relajación. Resultados: estudiamos a 76 pacientes, con una edad promedio de 34 años; 36 se asignaron al grupo 1 y 40 al 2. La evaluación inicial de ambos fue de 7.8, en tanto que la calificación final del grupo 1 fue de 9.3 y la del 2, de 8.4. El grupo 1 tuvo menor número de hospitalizaciones que el 2 (p-0.005), menor cantidad de consultas de urgencias (p-0.005) y una mejoría global superior a la del grupo 2, en el que sólo ocho pacientes se aliviaron. Una tercera parte del grupo 1 abandonó el tratamiento, mientras que esta cifra fue de 79 por ciento en el grupo 2 (p < 0.0005). Conclusiones: los programas educativos para pacientes asmáticos adultos disminuyen la gravedad de la enfermedad y el número de crisis y hospitalizaciones, además de incrementar el apego al tratamiento.

[Results of an education program for adult asthmatics]. / Resultados de un programa educativo para adultos asmáticos.

Bronchial asthma is a chronically disease with huge social economical consequences. Educational programs, which have been design for asthmatic patients and diminish asthma mobility and reduce medical cost. They also improve the patients quality of life. We show the results of our educational programs for asthmatic adults which were evaluated through a questionnaire applied to these patient one year after the program was introduced. The results show decreased of medicine required asthmatic crisis.

[Results of an educational program for adults with asthma]. / Resultados de un programa educativo para adultos con asma.

BACKGROUND: Asthma is a world health problem. Education of asthmatic patient has been proposed as a choice for diminishing mortality due to asthma. OBJECTIVE: To demonstrate that educational programs for asthmatic patients help to reduce disease's severity, crises and hospitalizations number and encourage a bigger therapeutic compliance. MATERIAL AND METHODS: 80 asthmatic patients were divided into two groups; first one received educational curse and second one does not. All patients received treatment according to international guides, including monthly consultation, flow-meter, and symptoms day book; an initial and final evaluation was made about disease's knowledge. Course consisted of a workshop including crisis management, use of inhaled medication, flow-metry and relaxation techniques. RESULTS: We studied 76 patients, with a mean age of 34 years; 36 were assigned to group 1 and 40 to group 2. Initial assessment of both groups was of 7.8, while final evaluation of groups 1 and 2 was of 9.3 and 8.4, respectively. Group 1 had lesser number of hospitalizations than group 2 (p-0.005), lesser number of emergency consultations (p-0.005) and a higher overall improvement than group 2, in which only 8 patients got well. A third part of the group 1 abandoned treatment, while patients that abandoned treatment in group 2 accounted for 79% (p < 0.0005). CONCLUSIONS: Educational programs for asthmatic adult patients diminish severity of disease, number of crises and hospitalizations, and also increase therapeutic compliance.

[Hyper-IgE syndrome treated with interferon alpha 2 beta. Report of a case]. / Síndrome de hiper IgE con tratamiento de interferón alfa 2 beta. Reporte de un caso.

The hyper IgE syndrome is characterized by recurrent abscess on the skin, and airways and itching dermatitis. The data acquired in the lab is hypergammaglobulinemy, eosinophil in blood, tissue, sputum, with fagocitos, and quimiotaxis defect. Since 1972 it has been reported 150 cases in the world without no geographic difference and 2:1 relation with the masculine gender. The therapeutic ways are even controversial. The therapy with interferon alpha 2 beta is the alternative treatment so diminish the dermis inflammation as the seric IgE reduction. This case shows a patient with the classic clinic data and seric IgE levels who didn't present response to the habitual therapy, because of this. He was the switch to the interferon alpha 2 beta. Later on the therapy it wasesented clinical changes over the symptomatology with reduction in the over seric IgE.

[Combined treatment in recurrent laryngeal papillomatosis with CO2 laser microlaryngoscopic resection and interferon alpha 2b]. / Tratamiento combinado en papilomatosis laríngea recidivante con resección microlaringoscópica láser CO2 e lfn alpha 2b.

Laryngeal papillomatosis of viral origin and bad prognosis is characterized by multiple recurrence that induced obstruction of air pathways. Surgical remove with laser CO2 is the elected treatment and the its combination with interferon (INF) has improved the prognosis of this recurrent viral disease. Here is a presents a preliminary study based upon such therapeutic scheme. Twelve patients diagnosed with laryngeal papillomatosis; 6 women and 6 men from 32 to 72 years of age were included into two therapeutic schemes: Group B, Combined: One woman and 5 men to whom the surgical procedure was followed by a initial local dose of 3 x 10(6) IU of INF alpha 2b (Intron A) and subsequently 10 X 10(6) (of the same INF were administered intramuscular every days during 15 months the statistical analysis (Fisher test) between patients of the both groups of treatment showed a significant (p < 0.0001) clinical improvement of the patients who received the combined treatment (B). In this group of patients was found incidence of the collateral effects such as: headache, fever arthralgias, depression and anorexia.

[Immunotherapy in allergy]. / La inmunoterapia en la alergia.

This report includes a partial interpretation of the possible mechanisms of action related with the efficacy of specific immunotherapy with allergens. This cannot be explained by only one mechanism which regulates the immune reaction, which is why there is the relief that there is a large field in immunology which has yet to be explore.

[Use of transfer++factor in allergic bronchial asthma]. / Uso del factor de transferencia en el asma bronquial alérgica.

The therapeutic panorama of immunomodulation and its effects on the modification of the immune reaction is reviewed. Particular reference is made to the transfer factor as a therapeutic element in bronchial asthma, which insures its efficacy or innocuity.

[The importance of pollinosis in the Valley of Mexico]. / La importancia de la polinosis en el Valle de México.

The climatic conditions and the vegetation in the valley of Mexico are analyzed in virtue of their modification during the last few years which have consequently altered the surrounding ecological systems. In this article, we were particularly interested in describing the botanical characteristics of the gimnospermas, an abundant vegetation in Mexico.

[Symptomatic dermatographism and HLA antigens]. / Dermografismo sintomático y antígenos HLA.

This research reports the unique case of manifestation of symptomatic dermographism which includes all of its twenty five members of the family. Probing a genetic transmission autosomal dominant manner and taking into account the highly probable role of HLA in this illness. The symptomatic dermographism correspond to a group of physical familiar urticarias with symptoms appearing in early childhood and evolving throughout adulthood with seldom periods of remission. Due to the fact that all patients were affected, it was not possible to realize a typification of HLA antigens with persons not affected, to establish a relationship with the data obtained. However, results show a significant association of haplotypes; HLA A2 (78.95), B16 (68.4%), A1 (47.3%), and B5 (42.5%) among the most important. This is the first research that reports the analysis of HLA within the physical familial urticarias.