Traumatic life-events and suicidality among Mexican adolescents as they grow up: A longitudinal community survey.

OBJECTIVE: Limited research exists on the impact of type and number of traumatic events on the incidence of suicide ideation and attempts (suicidality) among adolescents in low/middle income countries where violence is common. METHOD: We estimated prospective associations of 7 types of events on the new occurrence of suicidality from a follow-up conducted in 2013 (n = 1071; ages 19-26) of the original Mexican Adolescent Mental Health Survey conducted in 2005 (ages 12-17), by using Hazard Ratios (HR) estimates. RESULTS: For new onset of suicide ideation, those reporting "Ever raped or sexually assaulted" had the highest adjusted HR (3.8), followed by "Ever other traumatic event" (HR = 1.9), "Ever committed or witnessed violence" (HR = 1.7) and "Beaten as a child or witnessed physical fights at home" (HR = 1.5). For suicide attempt, those reporting "Ever beaten up by spouse, partner, someone else, mugged with a weapon, or stalked" (HR = 3.8) and "Ever other traumatic event" (HR = 2.0) had the higher hazards. Compared to those without a traumatic event, increased hazards of ideation and attempt were found for those reporting a greater number of types of events. CONCLUSIONS: Our sample is representative of the largest metropolitan area in Mexico but does not include other cities or age groups that may differ in risk factors. Traumatic events that happened in the eight years between waves are not considered. Traumatic events increased the risk of suicidality, independent of common mental disorders. Identifying and addressing these events in clinical settings may therefore be important for preventing suicide in this population.

Suicidal ideation and planning among Mexican adolescents are associated with depression polygenic risk scores.

Suicide is a major public health problem in Mexico and around the world. Genetic predisposition for major depressive disorder (MDD) has been associated with increased risk for suicidal behaviors (SB) in populations of European ancestry (EA). Here, we examine whether MDD polygenic risk scores (MDD PRS), derived from a genome-wide association study involving EA individuals, predict SB, including ideation, planning, and attempt, among Mexican youth using a longitudinal design. At baseline, participants (N = 1,128, 12-17 years, 55% women) were interviewed and genotyped as part of a general population survey on adolescent mental health. Eight years later, they were recontacted for a follow up visit (N = 437, 20-25 years, 63% women). At both assessments, individuals reported on their engagement in SB within the past year. MDD PRS were significantly positively associated with SB, particularly suicide ideation and planning during adolescence, accounting for ~4-5% of the variance in these outcomes. In contrast, associations between MDD PRS and SB during young adulthood did not reach statistical significance. Our results suggest that increased genetic liability for depression increased risk for SB, particularly during adolescence, expanding our knowledge of the genetic underpinnings of SB.

Prevalence of 12-month mental and substance use disorders in sexual minority college students in Mexico.

PURPOSE: Mental health disparities have been documented among sexual minority college students, but there is a dearth of evidence from developing countries. The aim is to estimate the prevalence of 12-month mental and substance use disorders across a range of sexual identities among first-year college students in Mexican universities, and test whether there is an association between sexual identity and disorders and whether the association is moderated by gender. METHOD: The University Project for Healthy Students, a web-based survey conducted as part of the World Health Organization's World Mental Health International College Student initiative, recruited 7874 students from nine Mexican universities in 2016 and 2017. Logistic regressions estimated the association of sexual identity with 12-month major depressive episode, generalized anxiety disorder, panic disorder, alcohol abuse/dependence, and drug abuse/dependence, with interaction terms for gender. RESULTS: Compared to heterosexual students reporting no same-sex attraction (SSA), heterosexual students with SSA (AORs range 1.77-3.67) and lesbian/gay and bisexual students (AORs range 2.22-5.32) were at a higher risk for several disorders. Asexual students were at higher risk for drug abuse/dependence (AOR = 3.64). Students unsure of their sexual identity were at a higher risk for major depressive episode, panic disorder, and drug abuse/dependence (AORs range 2.25-3.82). Gender differences varied across sexual identity and disorder. CONCLUSION: These findings are the first empirical report of sexual minority psychiatric disparities among a college student population from a developing nation and underscore the importance of clinical interventions that address mental health needs among sexual minority college students.

(Internet) Gaming Disorder in DSM-5 and ICD-11: A Case of the Glass Half Empty or Half Full: (Internet) Le trouble du jeu dans le DSM-5 et la CIM-11: Un cas de verre à moitié vide et à moitié plein.

BACKGROUND: Diagnostic and Statistical Manual of Mental Disorders (DSM-5) included in 2013 Internet gaming disorder (IGD) as a condition for further study, and in 2018, the World Health Organization included gaming disorder (GD) as a mental disorder in the International Classification of Disease (ICD-11). We aim to compare disorders of gaming in both diagnostic systems using a sample of young adults in Mexico. METHODS: Self-administered survey to estimate the prevalence of DSM-5 IGD and ICD-11 GD in 5 Mexican universities; 7,022 first-year students who participated in the University Project for Healthy Students, part of the World Health Organization World Mental Health International College Student Initiative. Cross-tabulation, logistic regression, and item response theory were used to inform on 12- month prevalence of DSM-5 IGD and ICD-11 GD, without and with impairment. RESULTS: The 12-month prevalence of DSM-5 IGD was 5.2% (95% CI, 4.7 to 5.8), almost twice as high as the prevalence using the ICD-11 GD criteria (2.7%; 95% CI, 2.4 to 3.1), and while adding an impairment requirement diminishes both estimates, prevalence remains larger in DSM-5. We found that DSM-5 cases detected and undetected by ICD-11 criteria were similar in demographics, comorbid mental disorders, service use, and impairment variables with the exception that cases detected by ICD-11 had a larger number of symptoms and were more likely to have probable drug dependence than undetected DSM-5 cases. CONCLUSION: DSM-5 cases detected by ICD-11 are mostly similar to cases undetected by ICD-11. By using ICD-11 instead of DSM-5, we may be leaving (similarly) affected people underserved. It is unlikely that purely epidemiological studies can solve this discrepancy and clinical validity studies maybe needed.

Suicide thought and behaviors, non-suicidal self-injury, and perceived life stress among sexual minority Mexican college students.

BACKGROUND: Sexual minority college students are at a higher risk for suicidal thoughts and self-injurious behaviors compared to heterosexual students. Minority stress theory proposes sexual minority individuals experience higher stress due to stigma. Using a sample of Mexican college students, this study tested perceived life stress as a mediator of suicide and self-injury outcomes across various sexual orientation groups. METHODS: The sample of college students (N=7882) was recruited from nine Mexican universities as part of the WHO World Mental Health International College Student (WMH-ICS) initiative. Participants completed an online survey including demographic questions, measure of perceived life stress, suicide outcomes, and non-suicidal self-injury (NSSI) in the past 12 months. RESULTS: Logistic regression analyses revealed identifying as a sexual minority significantly predicted a higher likelihood of suicide ideation (ORs 2.05-3.00), suicide attempts (ORs 2.48-8.73), and NSSI (ORs 2.92-4.18) compared to heterosexual students reporting no same-gender attraction. Significant indirect effects from mediation path analyses showed perceived life stress mediated the relationship between a sexual minority identity and suicide ideation (range of proportion mediated 10.48-31.48%), attempts (10.48-31.48%), and NSSI (7.69-20.09%) across each group except among asexual students. LIMITATIONS: The cross-sectional nature of the survey design precludes drawing causal inferences. CONCLUSION: Findings from this study contribute to minority stress theory by elucidating the role of perceived life stress as a mediator of suicide ideation and attempts and NSSI among sexual minority college students. Clinical interventions may benefit in focusing on experiences of stress across various life areas when supporting sexual minority college students.

Entanglement on an optical atomic-clock transition.

State-of-the-art atomic clocks are based on the precise detection of the energy difference between two atomic levels, which is measured in terms of the quantum phase accumulated over a given time interval1-4. The stability of optical-lattice clocks (OLCs) is limited both by the interrupted interrogation of the atomic system by the local-oscillator laser (Dick noise5) and by the standard quantum limit (SQL) that arises from the quantum noise associated with discrete measurement outcomes. Although schemes for removing the Dick noise have been recently proposed and implemented4,6-8, performance beyond the SQL by engineering quantum correlations (entanglement) between atoms9-20 has been demonstrated only in proof-of-principle experiments with microwave clocks of limited stability. The generation of entanglement on an optical-clock transition and operation of an OLC beyond the SQL represent important goals in quantum metrology, but have not yet been demonstrated experimentally16. Here we report the creation of a many-atom entangled state on an OLC transition, and use it to demonstrate a Ramsey sequence with an Allan deviation below the SQL after subtraction of the local-oscillator noise. We achieve a metrological gain of [Formula: see text] decibels over the SQL by using an ensemble consisting of a few hundred ytterbium-171 atoms, corresponding to a reduction of the averaging time by a factor of 2.8 ± 0.3. Our results are currently limited by the phase noise of the local oscillator and Dick noise, but demonstrate the possible performance improvement in state-of-the-art OLCs1-4 through the use of entanglement. This will enable further advances in timekeeping precision and accuracy, with many scientific and technological applications, including precision tests of the fundamental laws of physics21-23, geodesy24-26 and gravitational-wave detection27.

Incidence and recurrence of depression from adolescence to early adulthood: A longitudinal follow-up of the Mexican Adolescent Mental Health Survey.

BACKGROUND: Depression is a leading cause of disease burden around the globe, often develops during adolescence and is recurrent. Thus, disentangling risk factors for incidence from those of recurrence during adolescence is relevant and might suggest different strategies for prevention of onset than for relapse. The aim was to evaluate the relative risk of socio-demographic and clinical factors and traumatic events associated to incidence and recurrence of depression in youth from Mexico City. METHODS: This is a prospective longitudinal general population survey in which 1071 respondents from the Mexican Adolescent Mental Health Survey were interviewed between the ages of 12 and 17 and again eight years later when they were between 19 and 26 years of age. The World Mental Health Composite International Diagnostic Interview evaluated incidence and persistence of major depression and risk factors. RESULTS: Eight-year incidence was 12.9% while recurrence was 46.1%. Risk factors for incidence (female sex, any incident trauma, and specifically sexual abuse and an other/private event) differed from the risk factors for recurrence (childhood onset and domestic violence) with the exception of having a parent with depression, which was associated to increased risk for both. LIMITATIONS: The follow-up response rate was limited by inability to locate participants at wave II. Statistical power was limited for persistence due to low rate of depression at wave I. CONCLUSIONS: Intervening with both depressed and non-depressed children of parents with depression may have beneficial effects on both the development of depression as well as recurrence.

DSM-5 Internet gaming disorder among a sample of Mexican first-year college students.

BACKGROUND AND AIMS: DSM-5 includes Internet gaming disorder (IGD) as a condition for further study. While online and offline gaming may produce undesired negative effects on players, we know little about the nosology of IGD and its prevalence, especially in countries with emerging economies. METHODS: A self-administered survey has been employed to estimate prevalence of DSM-5 IGD and study the structure and performance of an instrument in Spanish to measure DSM-5 IGD among 7,022 first-year students in 5 Mexican universities that participated in the University Project for Healthy Students (PUERTAS), part of the World Health Organization's World Mental Health International College Student Initiative. RESULTS: The scale for IGD showed unidimensionality with factor loadings between 0.694 and 0.838 and a Cronbach's α = .816. Items derived from gaming and from substance disorders symptoms mixed together. We found a 12-month prevalence of IGD of 5.2% in the total sample; prevalence was different for males (10.2%) and females (1.2%), but similar for ages 18-19 years (5.0%) and age 20+ (5.8%) years. Among gamers, the prevalence was 8.6%. Students with IGD were more likely to report lifetime psychological or medical treatment [OR = 1.8 (1.4-2.4)] and any severe role impairment [OR = 2.4 (1.7-3.3)]. Adding any severe role impairment to the diagnostic criteria decreased the 12-month prevalence of IGD to 0.7%. DISCUSSION AND CONCLUSIONS: Prevalence of DSM-5 IGD and the performance of diagnostic criteria in this Mexican sample were within the bounds of what is reported elsewhere. Importantly, about one in every seven students with IGD showed levels of impairment that would qualify them for treatment under DSM-5.

Próxima escasez de enfermeras en España: el problema del que no se habla / The coming shortage of nurses in Spain: an unnoticed problema

OBJETIVO PRINCIPAL: Estimar la diferencia entre la oferta y la demanda de enfermeras en España en 2020, 2030, 2040 y 2050. METODOLOGÍA: Se han utilizado las proyecciones de población total, de población mayor de 65 años y de población entre 15 y 64 años para los años 2020, 2030, 2040 y 2050 facilitadas por Eurostat. Se ha estimado la oferta y la demanda de enfermeras extrapolando las ratios de 2016 a las cifras de población proyectadas para esos años. Resultados principales: se estima que en España la diferencia entre oferta y demanda de enfermeras podría ser de +21.024 (en 2020), +4.724 (en 2030), -23.155 (en 2040) y -39.510 (en 2050). Conclusión principal: Nuestras estimaciones sugieren que a partir de 2030 podría producirse escasez de profesionales de enfermería en España. Actualmente, pese a existir suficientes profesionales, dicha escasez se manifiesta de forma puntual en algunos puntos del país

OBJECTIVE: to estimate the gap between the supply and demand of nurses in Spain for 2020, 2030, 2040 and 2050. METHODS: we used the last population projections for total population and two age groups (ages 15 to 64, and older than 64) by Eurostat. Nurses supply and demand was estimated by extrapolating the 2016 nurses/population ratios for 2020, 2030, 2040 and 2050. RESULTS: we have estimated a gap of nurses of +21.024 (2020), +4.724 (2030), -23.155 (2040) and -39.510 (2050). CONCLUSIONS: These figures suggets that there may be a shortage of nurses in Spain from 2030. However, despite there are currently enough professionals, sometimes there is a shortage of nurses in certain areas in Spain

Near-Unitary Spin Squeezing in

Spin squeezing can improve atomic precision measurements beyond the standard quantum limit (SQL), and unitary spin squeezing is essential for improving atomic clocks. We report substantial and nearly unitary spin squeezing in ^{171}Yb, an optical lattice clock atom. The collective nuclear spin of ∼10^{3} atoms is squeezed by cavity feedback, using light detuned from the system's resonances to attain unitarity. The observed precision gain over the SQL is limited by state readout to 6.5(4) dB, while the generated states offer a gain of 12.9(6) dB, limited by the curvature of the Bloch sphere. Using a squeezed state within 30% of unitarity, we demonstrate an interferometer that improves the averaging time over the SQL by a factor of 3.7(2). In the future, the squeezing can be simply transferred onto the optical-clock transition of ^{171}Yb.

Spin transport in a Mott insulator of ultracold fermions.

Strongly correlated materials are expected to feature unconventional transport properties, such that charge, spin, and heat conduction are potentially independent probes of the dynamics. In contrast to charge transport, the measurement of spin transport in such materials is highly challenging. We observed spin conduction and diffusion in a system of ultracold fermionic atoms that realizes the half-filled Fermi-Hubbard model. For strong interactions, spin diffusion is driven by super-exchange and doublon-hole-assisted tunneling, and strongly violates the quantum limit of charge diffusion. The technique developed in this work can be extended to finite doping, which can shed light on the complex interplay between spin and charge in the Hubbard model.

Persistence of Specific Phobia From Adolescence to Early Adulthood: Longitudinal Follow-Up of the Mexican Adolescent Mental Health Survey.

BACKGROUND: Specific phobia is one of the most common psychiatric disorders in the general population, begins at a younger age, and has high comorbidity. However, it receives less treatment than other disorders, perhaps because it is circumscribed to a specific object or situation that can be avoided or is difficult to differentiate from developmentally adaptive fear. Longitudinal studies are needed to clarify its clinical significance, risk factors, and course. This study was designed to determine the persistence of specific phobia in participants during an 8-year period from adolescence to young adulthood and its predictors in a Mexican cohort. METHODS: 1,071 respondents from a representative 2-wave panel sample participated in the Mexican Adolescent Mental Health Survey in 2005 and in the follow-up survey in 2013. DSM-IV disorders were evaluated with the World Mental Health Composite International Diagnostic Interview. RESULTS: Of adolescents with specific phobia at baseline, 17.46% persisted into adulthood. Persistence of specific phobia was predicted by an age of onset of disorder in adolescence (risk ratio [RR] = 2.83, 95% CI, 1.30-6.13), parental neglect (RR = 2.76, 95% CI, 1.35-5.65), a first-degree relative with specific phobia (RR = 2.69, 95% CI, 1.34-5.39) and economic adversities (RR = 2.06, 95% CI, 1.21-3.53). Noncomorbid specific phobia in adolescence predicted incidence of other anxiety and substance use disorders in early adulthood (RR = 1.98; 95% CI, 1.11-3.54 and RR = 1.35; 95% CI, 1.07-1.69, respectively). CONCLUSIONS: While many adolescents with specific phobia remit in adulthood, there are early adult consequences of adolescent phobia and identifiable risk factors for persistence that suggest a group of adolescents that might benefit from early intervention.

Non-suicidal self-injury in Mexican young adults: Prevalence, associations with suicidal behavior and psychiatric disorders, and DSM-5 proposed diagnostic criteria.

BACKGROUND: Non-suicidal self-injury (NSSI) may lead to scarring, infection, accidental death and psychological distress. Little is known about NSSI in the general population of young adults in developing countries like Mexico. The current study examined the prevalence of any NSSI and each type of NSSI, the prevalence of meeting DSM-5 proposed criteria, and finally the association of NSSI with socio-demographic variables, suicidal behavior and psychiatric disorders. METHODS: This study was conducted in a community sample of 1071 young adults between 19 and 26 years of age residents of Mexico City. RESULTS: The lifetime prevalence of NSSI was 18.56% with females having 87% greater odds. The 12-month prevalence was 3.19%. Only 0.22% of the total sample and 6.96% of those that self-injured in the past 12 months met full criteria proposed by DSM-5, in part due to the lack of reported impairment; 39.99% of those that self-injured reported impairment. Suicidal behavior commonly co-occurred with NSSI. All lifetime anxiety, mood, disruptive behavior and substance use disorders were associated with greater risk for lifetime NSSI whereas only 12-month depression and substance use disorder was associated with greater risk of 12-month NSSI. LIMITATIONS: The cross-sectional nature of the study precludes conclusions of causality and directionality and the study excluded institutionalized and homeless young adults. CONCLUSIONS: NSSI is a concerning problem in young adults from Mexico City due to the important associations with all types of psychiatric disorders and suicidal behavior. Because many who self-injure do not perceive impairment, they are unlikely to seek treatment.

How Mental Health Interviews Conducted Alone, in the Presence of an Adult, a Child or Both Affects Adolescents' Reporting of Psychological Symptoms and Risky Behaviors.

The normative process of autonomy development in adolescence involves changes in adolescents' information management typically characterized by decreasing disclosure and increasing concealment. These changes may have an important impact on the early detection and timely treatment of mental health conditions and risky behavior. Therefore, the objective was to extend our understanding of how these developmental changes in adolescent disclosure might impact adolescent mental health interviews. Specifically, we estimated the effects of third party presence and type of third party presence (adult, child, or both) on adolescents' reports of psychiatric symptoms, substance use, suicidal behavior, and childhood adversity. In this representative sample of 3005 adolescents from Mexico City (52.1 % female), administered the World Mental Health Composite International Diagnostic Interview (WMH-CIDI-A), adult presence influenced reporting the most; in their presence, adolescents reported more ADHD, parental mental illness and economic adversity, but less panic disorder, PTSD, drug use and disorder, and suicidal behavior. The presence of children was associated with increased odds of reporting conduct disorder, opportunity for drug use, parental criminal behavior, neglect, and the death of a parent. While adolescent information management strategies are normative and even desirable as a means of gaining emotional autonomy, they may also interfere with timely detection and treatment or intervention for mental health conditions and risky behaviors. Research and practical implications of these findings are discussed.

Applying the COM-B model to creation of an IT-enabled health coaching and resource linkage program for low-income Latina moms with recent gestational diabetes: the STAR MAMA program.

BACKGROUND: One of the fastest growing risk groups for early onset of diabetes is women with a recent pregnancy complicated by gestational diabetes, and for this group, Latinas are the largest at-risk group in the USA. Although evidence-based interventions, such as the Diabetes Prevention Program (DPP), which focuses on low-cost changes in eating, physical activity and weight management can lower diabetes risk and delay onset, these programs have yet to be tailored to postpartum Latina women. This study aims to tailor a IT-enabled health communication program to promote DPP-concordant behavior change among postpartum Latina women with recent gestational diabetes. The COM-B model (incorporating Capability, Opportunity, and Motivational behavioral barriers and enablers) and the Behavior Change Wheel (BCW) framework, convey a theoretically based approach for intervention development. We combined a health literacy-tailored health IT tool for reaching ethnic minority patients with diabetes with a BCW-based approach to develop a health coaching intervention targeted to postpartum Latina women with recent gestational diabetes. Current evidence, four focus groups (n = 22 participants), and input from a Regional Consortium of health care providers, diabetes experts, and health literacy practitioners informed the intervention development. Thematic analysis of focus group data used the COM-B model to determine content. Relevant cultural, theoretical, and technological components that underpin the design and development of the intervention were selected using the BCW framework. RESULTS: STAR MAMA delivers DPP content in Spanish and English using health communication strategies to: (1) validate the emotions and experiences postpartum women struggle with; (2) encourage integration of prevention strategies into family life through mothers becoming intergenerational custodians of health; and (3) increase social and material supports through referral to social networks, health coaches, and community resources. Feasibility, acceptability, and health-related outcomes (weight loss, physical activity, consumption of healthy foods, breastfeeding, and glucose screening) will be evaluated at 9 months postpartum using a randomized controlled trial design. CONCLUSIONS: STAR MAMA provides a DPP-based intervention that integrates theory-based design steps. Through systematic use of behavioral theory to inform intervention development, STAR MAMA may represent a strategy to develop health IT intervention tools to meet the needs of diverse populations. TRIAL REGISTRATION: ClinicalTrials.gov NCT02240420.

Eight-year incidence of psychiatric disorders and service use from adolescence to early adulthood: longitudinal follow-up of the Mexican Adolescent Mental Health Survey.

Half of mental disorders have their first onset before adulthood when the presence of a disorder may be particularly disruptive to developmental milestones. Retrospective prevalence estimates have been shown to underestimate the burden of mental illness and scarce data are available on the incidence of disorders throughout the adolescent period, especially in developing countries. Thus, the objective was to determine the incidence of mental disorders in an 8-year period from adolescence to young adulthood, onset of service use and their predictors in a Mexican cohort. 1071 respondents from a representative two-wave panel sample participated in the Mexican Adolescent Mental Health Survey in 2005 and in the follow-up survey in 2013. Disorders were evaluated with the World Mental Health Composite International Diagnostic Interview. 37.9% experienced the onset of a psychiatric disorder and 28.4% sought services for the first time. Substance use disorders had the greatest incidence, followed by mood and behavior disorders, anxiety disorders and lastly eating disorders. Sex, age, school dropout, childhood adversities and prior mental disorders predicted the onset of new disorders. Being female, having more educated parents and most classes of disorder predicted first time service use. These findings contribute to a paradigm shift in conceptions of mental disorder similar to how we think of common physical afflictions as near universal experiences across the life course, but less frequent at any given moment. Adolescents are particularly vulnerable. Therefore, public health policy should focus on early universal promotion of positive mental health and structural determinants of mental health.

Adolescent alcohol use and alcohol use disorders in Mexico City.

OBJECTIVE: To estimate the prevalence, sex, age distribution, and socio-demographic correlates of any alcohol use, consumption patterns, and any alcohol use disorder in a representative sample of Mexican adolescents. METHODS: 3005 youth (52.1% female) aged 12-17 from a stratified multistage area probability sample were representative of adolescents residing in the Mexico City Metropolitan Area. Alcohol use and disorder and their socio-demographic correlates were evaluated with the World Mental Health adolescent version of the Composite International Diagnostic Interview. Data were post-stratified to the total Mexico City adolescent population. RESULTS: 59% has used alcohol, this proportion increasing significantly with age. By age 17, 82.5% has used alcohol. Consumption patterns are mostly of low/moderate quantity or infrequent high quantity. Lifetime DSM-IV alcohol use disorder criteria are met by 3.8%, reaching 8.1% for 16-17 years-olds. While males have greater frequency and quantity of drinking, there are no gender differences for alcohol use disorders. Non-school attending youth have twice the odds of a lifetime (OR=2.0, 95% CI=1.13-3.53) and 12-month disorder (OR=2.1, 95% CI=1.10-4.15). Low parental monitoring is associated with 1.72 times the odds of a lifetime disorder (95% CI=1.10-2.68). CONCLUSIONS: Over a third of 12 year-olds had ever drunk an alcoholic beverage in their lifetime suggesting that the prevention of alcohol use and disorders must begin in late childhood. Initiatives to foment parental monitoring and to prevent, identify, and treat alcohol use problems in non-school attending youth in particular should be a priority for the wellbeing of Mexico City adolescents.

Chronic childhood adversity and stages of substance use involvement in adolescents.

BACKGROUND: Studies have shown that those who experience chronic childhood adversity have a greater likelihood of substance abuse and dependence. However, substance use disorders are first preceded by substance use, and substance use is preceded by substance use opportunities. This study aims to estimate the association of chronic adversity with different stages of substance involvement: opportunities, use given the opportunity and abuse or dependence given use. METHODS: 3005 adolescents aged 12-17 were interviewed in a stratified multistage general population probability survey of Mexico City, Mexico. Substance involvement and chronic childhood adversities were assessed with the World Mental Health Composite International Diagnostic Interview Adolescent Version (WMH-CIDI-A). Discrete-time survival models were performed; their survival coefficients and standard errors were exponentiated, and reported as odds-ratios (ORs). RESULTS: Childhood adversities were associated with alcohol opportunity, alcohol use and alcohol abuse/dependence with significant ORs for individual adversities ranging from 1.4 to 4.1. Childhood adversities were also associated with illicit drug opportunity, drug use and drug abuse/dependence with significant ORs for individual adversities ranging from 1.6 to 17.3. Having more adversities was associated with greater incremental odds of substance involvement, particularly drug use given the opportunity. CONCLUSIONS: While adversities are mostly related to transitioning into use and disorder, a few are related to substance opportunities, particularly those which were likely to make substances available through parents. Attending to the needs of youth living in adversity, particularly adversities related to parental dysfunction and child abuse should be integral to addiction prevention efforts.

Epidemiología de los trastornos de la conducta alimentaria en una muestra representativa de adolescentes / Epidemiology of eating disorders in a representative sample of adolescents

Objetives The objective of this article is to estimate the prevalence of DSM-IV anorexia nervosa, bulimia nervosa and binge-eating disorder in the general adolescent population of the Mexico City Metropolitan Area. A further objective is to describe socio-demographic and clinical characteristics of youth who meet criteria for these disorders, the proportion with impairment, psychiatric comorbidity and suicidal behavior, as well as to estimate service utilization. Methods The data come from the Mexican Adolescent Mental Health Survey, a probablistic multi-stage survey representative of adolescents between 12 and 17 years of age, residents of the Mexico City Metropolitan Area. Trained interviewers administered face-to-face the World Mental Health computerized adolescent version of the Composite International Diagnostic Interview (WMH-CIDI-A) to 3005 adolescents in their homes. The response rate was 71%. Results The lifetime prevalence of anorexia, bulimia and binge-eating disorder in the Mexico City adolescent population is 0.5%, 1.0% and 1.4%, respectively. Between 83% and 100% report any impairment and all of those with anorexia and almost half of those with bulimia and binge-eating disorder report serious impairment. However, only 14% to 24% of those with a 12-month eating disorder have sought treatment despite the associated impairment. There is greater prevalence of comorbid psychiatric disorders, suicidal behavior and psychosocial adversities in those with an eating disorder than in those without such a disorder. Conclusions These results clearly demonstrate a treatment gap for these disorders in our adolescent population. They highlight the importance of programs for the prevention of risky eating behaviors, early detection focusing on vulnerable groups such as those who have suffered adversity like sexual abuse, and the reduction of treatment seeking and utilization barriers.

Objetivos El presente trabajo tiene el objetivo de estimar la prevalencia de anorexia nervosa, bulimia nervosa y el trastorno por atracones en la población general de adolescentes del Distrito Federal. Asimismo se pretende proporcionar una descripción de las características socio-demográficas y clínicas de los jóvenes que cumplen criterios diagnósticos según el DSM-IV para estos trastornos, la proporción de discapacidad, comorbilidad psiquiátrica y conducta suicida para cada trastorno y estimar la utilización de servicios. Material y métodos Los datos provienen de la Encuesta Mexicana de Salud Mental Adolescente, una encuesta con diseño probabilístico y multietápico representativa de adolescentes entre los 12 y 17 años, residentes del Distrito Federal y área conurbada. Se entrevistó a 3005 adolescentes en sus hogares utilizando como instrumento diagnóstico la Entrevista Internacional Diagnóstica Compuesta (WMH-CIDI-A), aplicada cara a cara, por medio de una computadora portátil, por encuestadores capacitados. La tasa de respuesta fue de 71%. Resultados La prevalencia alguna vez de anorexia, bulimia y el trastorno por atracones se estima en 0.5%, 1.0% y 1.4%, respectivamente. Entre 83 y 100% reportan discapacidad y todos aquellos con anorexia y casi la mitad de aquellos con bulimia y atracones reportan discapacidad grave. Sin embargo, ni una cuarta parte con uno de estos trastornos ha recibido tratamiento a pesar de la discapacidad que generan. Hay mayor prevalencia de trastornos comórbidos, conducta suicida y adversidades psicosociales en jóvenes con trastornos alimentarios que en aquellos sin ellos. Conclusiones Los hallazgos muestran una brecha entre las necesidades de atención y el tratamiento para estos trastornos en nuestra población adolescente. Señalan la importancia de programas para la prevención de conductas alimentarias riesgosas, la detección temprana con un enfoque en grupos vulnerables (por ejemplo quienes han sufrido alguna adversidad como abuso sexual), y la reducción de barreras para la búsqueda y utilización de servicios.

Youth who neither study nor work: mental health, education and employment / Jóvenes que ni estudian ni trabajan: salud mental, educación y empleo

OBJECTIVE: Limited educational and job opportunities for youth has led to a phenomenon termed NEET (not in education, employment or training). The objective is to estimate the prevalence of psychiatric disorders, substance use and suicidal behavior in youth classified as NEET and to compare with those who study only, work only or do both. MATERIAL AND METHODS: 3 005 12-to-17 year-olds in Mexico City were evaluated in 2005 with the Composite International Diagnostic Interview. Descriptive and logistic regression analyses considered the multistage weighted sample design. RESULTS: NEET youth as well as those who work only or study and work simultaneously have greater odds of psychiatric disorder, substance use and suicidal behavior compared to those who study exclusively even after controlling for social disadvantage. CONCLUSION: Vulnerability is not circumscribed to NEET adolescents, but to all teens who are not exclusive students. Supporting youth to continue studying exclusively may buffer negative mental health outcomes.

OBJETIVO: Oportunidades educativas y laborales limitadas para los jóvenes han dado lugar al fenómeno de adolescentes que no estudian ni trabajan (NINIs). El objetivo es estimar la prevalencia de trastornos psiquiátricos, consumo de sustancias y conducta suicida en adolescentes NINIs y compararlos con adolescentes que estudian exclusivamente, trabajan exclusivamente y quienes estudian y trabajan. MATERIAL Y MÉTODOS: 3 005 adolescentes entre 12 y 17 años de edad fueron evaluados en 2005 con la Entrevista Internacional Psiquiátrica Compuesta en una encuesta multietápica, estraficada y representativa del Distrito Federal y municipios conurbados. RESULTADOS: Los NINIs, quienes trabajan, y quienes estudian y trabajan tienen mayor riesgo de trastornos psiquiátricos, consumo de sustancias y conducta suicida en comparación con aquellos que estudian exclusivamente. CONCLUSIÓN: La vulnerabilidad no se circunscribe a los NINIs sino a todos los que no son estudiantes exclusivamente. Apoyar a los jóvenes para que estudien podría beneficiar su salud mental.