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5.
An Med Interna ; 15(6): 298-300, 1998 Jun.
Artigo em Espanhol | MEDLINE | ID: mdl-9656508

RESUMO

BACKGROUND: To know the prevalence of Toxoplasma gondii latent infection in HIV-1 infected patients and to compare it with the prevalence in a group of parenteral drug users, non-infected by HIV. METHODS: We study 255 HIV-1 patients revised in our hospital in the last 6 years. The control group were 116 drug addicts non-infected by HIV followed in an educational program of deshabituation. We tested IgG anti-toxoplasma by enzymatic inmunoessay (MEIA). An IgG plasma value of 6UI/ML or more was an indicative of toxoplasma previous infection. We used Chi Square and Yatchts correction tests for the statistical analysis, settling down a significance point of 95%. RESULTS: We founded 36.7% positive IgG anti-toxoplasma in the group on HIV-1 infected patients, non drugs addicts, against 30.9% in the group of HIV-1 drug addicts patients. (OR 0.77; 0.35 < OR < 1.66). The control group showed a Toxoplasma seroprevalence of 26.7%, without statistically significant against the drug addicts HIV group (OR = 1.55; 0.93 < OREGON < 2.59). CONCLUSIONS: The seroprevalence of Toxoplasma gondii latent infection in our study was similar to the european results. We didn't found a higher prevalence in HIV-1 patients than in patients non infected by HIV-1.


Assuntos
Infecções por HIV/parasitologia , Abuso de Substâncias por Via Intravenosa/parasitologia , Toxoplasmose/epidemiologia , Adulto , Animais , Anticorpos Antiprotozoários/sangue , Feminino , Infecções por HIV/complicações , Humanos , Imunoglobulina G/sangue , Masculino , Testes Sorológicos , Toxoplasma/imunologia , Toxoplasmose/complicações , Toxoplasmose/diagnóstico
8.
An Med Interna ; 12(12): 576-83, 1995 Dec.
Artigo em Espanhol | MEDLINE | ID: mdl-8679799

RESUMO

From last years eighty's decade the number of women with HIV infection have significantly increased. To know the epidemiological and clinic trades in this group we studied retrospectively 476 HIV infected patients attending in a General Hospital from January 1986 to June 1993. Seventy nine (16.5%) were female and 397 male. The mean female group was 25.8 years, 61.9% were IVDUs and 30.4% heterosexual transmission. This last transmission route was more important between females than males (5%) (p < 0.001) and in 1992 the 55% of women been infected by this way. The mean CD4 count was 643 cel/ml in the female group at the diagnostic time and 21.7% developed antigenaemia without difference with the male group. 59.7% of women were no symptoms at the diagnosis time and 14.3% were AIDS, no differences with men, but more in the female group developed AIDS along following time 39.5% in front of 24.7% in the male group (p < 0.05). Disseminated Tuberculosis (DTB) (29.1%) and Wasting Syndrome (WS) (29.1%) were the more frecuent AIDS defining conditions in the female group. The more frecuent complications were: Oropharynx Candidiasis 39.1%, Esophagus Candidiasis 6.3%, WS 11%, DTB 12.65%, PCP 10.12% and Neoplasias 5.06%. Fourteen women became pregnant during HIV infection, no clinical nor immunological differences were observed in this group with the control. The treatment (66%) and following (46.8%), compliance was better between women than men. The rise of women with HIV infection, the poor development in this group described by some authors, so far gynecological aspect and vertical transmission makes HIV infection in women an major health problem.


Assuntos
Infecções por HIV/epidemiologia , Síndrome da Imunodeficiência Adquirida/complicações , Síndrome da Imunodeficiência Adquirida/epidemiologia , Síndrome da Imunodeficiência Adquirida/transmissão , Adulto , Feminino , Infecções por HIV/complicações , Infecções por HIV/transmissão , Humanos , Recém-Nascido , Masculino , Razão de Chances , Gravidez , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Fatores Sexuais , Espanha/epidemiologia , Abuso de Substâncias por Via Intravenosa/complicações
9.
Rev Clin Esp ; 194(2): 104-6, 1994 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-8008931

RESUMO

The epidemiology of retrovirus HTLV-II is scarcely known even though it appears to be narrowly related to parenteral drug addiction. In order to find out the prevalence of HTLV-II among IVDU in our area, the sera of 137 subjects who came to our center for clinical evaluation were analyzed. The presence of HTLV-I/II antibodies were determined via ELISA and the sera that were repeatedly reactive were confirmed by the Western blot technique which reveals infection by both retroviruses. Two sera were repeatedly positive by ELISA (1.45 percent). Western blot confirmed HTLV-II positivity in both sera. Serology for HIV-1 was positive in 52 sera (37.9%). The two HTLV-II positive sera were also positive for HIV-1. These results indicate that HTLV-II infection is already present in the IVDU population in our area, where, similar to what happens in the U.S. and Europe, this retrovirus is implicated in the majority of HTLV infections in IVDU.


Assuntos
Infecções por HTLV-II/epidemiologia , Abuso de Substâncias por Via Intravenosa/complicações , Anticorpos Anti-HTLV-II/sangue , Infecções por HTLV-II/sangue , Infecções por HTLV-II/complicações , Humanos , Estudos Soroepidemiológicos , Espanha/epidemiologia
11.
An Med Interna ; 9(6): 282-4, 1992 Jun.
Artigo em Espanhol | MEDLINE | ID: mdl-1623099

RESUMO

Medical problems related to cocaine consumption are not rare in our environment; however, to this respect, descriptions in the spanish literature are scarce. We present three cases of intracerebral hemorrhage which occurred after cocaine consumption (intranasal route in two cases and intravenous route in one case). In the three cases, another associated risk factor was observed (alcohol in one case, hypertension in other case, arteriovenous malformation in the third case). We comment on the pathophysiological theories of the cause of bleeding, high-lighting the routine search of this association.


Assuntos
Hemorragia Cerebral/etiologia , Cocaína , Transtornos Relacionados ao Uso de Substâncias/complicações , Adulto , Hemorragia Cerebral/fisiopatologia , Humanos , Masculino
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