RESUMO
OBJECTIVE: This systematic review aimed to evaluate the antiviral effect of mouthwashes against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MATERIAL AND METHODS: An electronic search was performed on PubMed, Scopus, Web of Science, Cochrane Library, LILACS, ProQuest, and Google Scholar, and was complemented by a manual search. Both clinical and in vitro studies that focused on the antiviral effect of mouthwashes against SARS-CoV-2 were included. Risk of bias assessment was performed only on the clinical studies using the RoB-2 and ROBINS-I tools. RESULTS: A total of 907 records were found; after initial selection by title and abstract, 33 full-text articles were selected to be evaluated for eligibility. Finally, a total of 27 studies were included for the qualitative synthesis, including 16 in vitro studies and 11 clinical trials. Antiviral effects were evaluated separately for the in vitro and clinical studies. In vitro studies included mouthwashes containing hydrogen peroxide, chlorhexidine digluconate, povidone-iodine, essential oils, cetylpyridinium chloride, and other compounds; in vivo studies included mouthwashes containing hydrogen peroxide, chlorhexidine digluconate, povidone-iodine, cetylpyridinium chloride, essential oils, chlorine dioxide, ß-cyclodextrin-citrox, and sorbitol with xylitol. Povidone-iodine, cetylpyridinium chloride, and essential oils were effective in vitro, while hydrogen peroxide, chlorhexidine digluconate, povidone-iodine, cetylpyridinium chloride, ß-cyclodextrin-citrox, and sorbitol with xylitol were effective in vivo. Unclear or high risk of bias was found for almost all clinical studies, and only one study presented with a low risk of bias. No further quantitative analysis was performed. CONCLUSION: Although povidone-iodine, cetylpyridinium chloride, and essential oils may be an alternative to reduce the viral load in vitro and in vivo, more studies are needed to determine the real antiviral effect of these different mouthwashes against SARS-CoV-2.This work was not funded. The protocol was registered in PROSPERO (identification number: CRD42021236134).
RESUMO
La caries dental en niños es una enfermedad multifactorial no transmisible, que produce desmineralización de los tejidos duros dentales y puede llegar a dañar la pulpa dental de forma irreversible. Cuando esto sucede, estamos ante 2 vías de tratamiento, la pulpotomía y la pulpectomía; esta última consiste en la eliminación de la pulpa cameral y de los conductos radiculares. Posterior a la pulpectomía, la pieza dental puede ser reforzada con la colocación de postes dentales, principalmente en el sector anterior, Debido a que no existe una clasificación u organización de los tipos de postes dentales utilizados en odontopediatría. El objetivo de este estudio es presentar una propuesta de clasificación, u organización de postes dentales utilizados en dentición decidua, basada en las clasificaciones de postes dentales en adultos. Para ello, se realizó una búsqueda bibliográfica en las bases de datos: PUBMED, MEDLINE, EBSCO, LILACS en idioma inglés, portugués y español, sin restricción de los años de publicación. Concluimos que no existe en la literatura una clasificación u organización de los postes, espigos o pines utilizados en odontopediatría, por lo cual presentamos una propuesta de clasificación con fines académicos y clínicos.
