Comparison of Seven Healthy Lifestyle Scores Cardiometabolic Health: Age, Sex, and Lifestyle Interactions in the NutrIMDEA Web-Based Study.

BACKGROUND: Global health status concerns both the assessment of wellbeing as well as the associated individualized determinants including quality of life and lifestyle factors. This study aimed to evaluate seven cardiometabolic health related scores and the influence, as well as interactions of lifestyle, heart-related and health-related quality of life (HRQoL) factors in order to inform the future implementation of precision public health (PPH). METHODS: Data collected from 17,333 participants who were enrolled of the NutrIMDEA study. The data collection period was between May 2020 and November 2020 through an online survey. The baseline questionnaire collected information on socio-demographic data, cardiometabolic history, anthropometric variables and lifestyle aspects. Also, physical and mental component scores of SF12 Health Survey (PCS12/MCS12) were assessed as HRQoL features, which were applied to estimated seven scores (LS7, HLS, 20-years DRS %, FBS, CLI, WAI derived, LWB-I). RESULTS: Most indices (except FBS, CLI, 20-years DRS % and WAI derived) showed that cardiometabolic outcomes and HRQoL measures were dependent on interactions by age and sex. The largest ponderal effect was found in PA total and Mediterranean Diet Score (MEDAS-14) interaction using LS7 as reference. However, using LWB-I as standard, the greatest effect was found in the quality-of-life feature MCS12. Noteworthy, LS7 showed good discrimination against PCS12, while LWB-I demonstrated excellent discrimination to MCS12. CONCLUSIONS: A major finding was the interplay between MEDAS-14 and PA on the LS7 scale as well as major effects of lifestyle factors and MCS12/PCS12 among scores, which need to be accounted with precision when implementing cardiometabolic screenings with PPH purposes.

Single-shot slightly off-axis digital holographic microscopy with add-on module based on beamsplitter cube.

Slightly off-axis digital holographic microscopy (SO-DHM) has recently emerged as a novel experimental arrangement for quantitative phase imaging (QPI). It offers improved capabilities in conventional on-axis and off-axis interferometric configurations. In this contribution, we report on a single-shot SO-DHM approach based on an add-on module adapted to the exit port of a regular microscope. The module employs a beamsplitter (BS) cube interferometer and includes, in addition, a Stokes lens (SL) for astigmatism compensation. Each recorded frame contains two fields of view (FOVs) of the sample, where each FOV is a hologram which is phase shifted by π rads with respect to the other. These two simultaneously recorded holograms are numerically processed, in order to retrieve complex amplitude distribution with enhanced quality. The tradeoff is done in the FOV which becomes penalized as a consequence of the simultaneous recording of the two holograms in a single snapshot. Experimental validation is presented for a wide variety of samples using a regular Olympus BX-60 upright microscope. The proposed approach provides an optimized use of the imaging system, in terms of the space-bandwidth product, in comparison with off-axis configuration; allows the analysis of fast-dynamic events, owing to its single-shot capability when compared with on-axis arrangement; and becomes easily implementable in conventional white-light microscopes for upgrading them into holographic microscopes for QPI.

Dual-mode holographic microscopy imaging platform.

We report on a novel layout capable of dual-mode imaging in real time with different magnifications and resolution capabilities in lensless microscopy. The concept is based on wavelength multiplexing for providing two illuminations with different wavefront curvatures: one is collimated, allowing a large field of view (FOV) with a poor resolution limit, and the other is divergent, to achieve a better resolution limit (micron range) over a small FOV. Moreover, our recently reported concept of MISHELF microscopy [M. Sanz, J. Á. Picazo-Bueno, L. Granero, J. García and V. Micó, Sci. Rep., 2017, 7, 43291] is applied to the divergent illumination case, improving the image quality by noise averaging and twin image minimization. The performance of this novel dual-mode lensless microscopy imaging platform is validated through experiments using both static amplitude (resolution test targets) and dynamic complex (flowing microbeads and live sperm cells) samples. The proposed imaging platform represents the background technology for a new generation of lensless microscopes with improved performance and capabilities.

Consejo nutricional en paciente oncológico / Nutritional advice in oncology

Introducción. El cáncer es la primera causa de muerte en España y es, por tanto, un problema de salud prioritario. Se sabe que la nutrición está relacionada con la incidencia de cáncer y que también puede ser un factor importante para su tratamiento. Es esencial otorgar a la nutrición el papel que merece, para llevar a cabo un tratamiento óptimo de la enfermedad y maximizar las probabilidades de curación. Objetivos: Evaluar la adecuación y la prevalencia de los consejos nutricionales que se ofrecen en materia de cáncer en distintos centros de España. Metodos: Estudio descriptivo, observacional, retrospectivo. Se realizó mediante un cuestionario Ad Hoc a una muestra incidental en pacientes con cáncer de 3 Comunidades Autónomas. Las variables estudiadas se centraron en la información sobre su tratamiento nutricional, sus características sociosanitarias, así como las de la intervención y evolución de cada participante. Resultados: La muestra estudiada es de 17 pacientes con distintos tipos de cáncer, que fueron sometidos a cirugía, quimioterapia, radioterapia y/u hormonoterapia. Refirieron haber tenido efectos secundarios 10 participantes y solo recibieron consejos adecuados para los síntomas en 2 de los casos. El 82,35% no tuvo valoración nutricional previa, solo un 5,88% fue a consulta exclusiva de nutrición y solo un 29,41% recibió alguna pauta alimentaria. Discusión: La eficacia de las recomendaciones nutricionales en la evolución y calidad de vida del paciente oncológico ha sido demostrada por diversos estudios. La malnutrición y la pérdida de peso son problemas comunes en estos pacientes y pueden dar origen a complicaciones durante la enfermedad. Por ello, es muy importante evaluar de forma correcta el estado nutricional del paciente para poder realizar la intervención nutricional oportuna, adaptada a sus necesidades, gustos y sintomatología. Lo cual no se identificó mayoritariamente en nuestra muestra. Conclusión: La evaluación, tratamiento y seguimiento del estado nutricional resulta muy importante para el paciente oncológico. Pero es a su vez un traba - jo complejo que requiere mucho tiempo y dedicación y, que debe manejarse a través de equipos especializados de nutrición con un alto grado de entrena miento en oncología (AU)

Introduction: Cancer is the main cause of death in Spain and is therefore a priority health problem. It is known that nutrition is associated with the incidence of cancer and can also be an important factor for treatment. It is essential to give the role nutrition it deserves, to perform optimal treatment of disease and maximize the chance of cure. Aim: evaluate the suitability and prevalence of nutritional advice given on cancer in different institutes in Spain. Methods: A descriptive, observational, retrospective study. Was performed using a questionnaire Ad hoc on one incidental sample in patients with cancer from 3 regions from Spain. The variables studied were focused on information about their nutritional treatment, their social and health characteristics, as well as intervention and progress of each participant. Results: The study sample of 17 patients with difference types of cancer, who underwent surgery, chemotherapy, radiotherapy and / or hormone therapy. Ten of them had effects and only 2 participants received appropriate advice for symptoms. From the sample, 82.35% had not previous nutritional assessment, only 5.88% was the exclusive nutritional consultant and only 29.41 % received any general food advices. Discussion: The effectiveness of nutritional recommendations on the development and quality of life of cancer patients has been demonstrated by several studies. Malnutrition and weight loss are common problems in these patients and can cause complications during illness. It is therefore very important to assess correctly the nutritional status of the patient in order to make timely nutrition intervention, adapted to needs, likes and symptomatology. Which is mostly not identified in our sample. Conclusion: The assessment, treatment and monitoring of nutritional status is very important to cancer patients. But it is itself a complex job that requires much time and dedication, and that must be manage by specialized teams of nutrition with a high training in oncology (AU)