RESUMO
A skeletal survey was carried out on 84 cases of haemoglobin SC disease. The radiological features noted were increased translucency of bone, abnormal trabecular pattern, medullary expansion, wide vascular channels in phalanges, and radiological evidence of infarction, both medullary and cortical. The frequency of bone lesions thus demonstrated increased with age. The most characteristic lesions in this region were those of vascular necrosis; contributing factors such as the high haemoglobin level characteristic of the condition are discussed. An interesting feature was the lack of correlation betweeen clinical severity and degree of radiological change. (AU)
Assuntos
Humanos , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Anemia Falciforme/diagnóstico por imagem , Doença da Hemoglobina C/diagnóstico por imagem , Anemia Falciforme/complicações , Osso e Ossos/irrigação sanguínea , Osso e Ossos/diagnóstico por imagem , Doenças Ósseas/diagnóstico por imagem , Reabsorção Óssea , Fêmur/diagnóstico por imagem , Necrose da Cabeça do Fêmur/complicações , Dedos/irrigação sanguínea , Dedos/diagnóstico por imagem , Doença da Hemoglobina C/complicações , Quadril/diagnóstico por imagem , Articulação do Quadril , Úmero/diagnóstico por imagem , Infarto , Jamaica , Vértebras Lombares/diagnóstico por imagem , Necrose/sangue , Osteoartrite/complicações , Periósteo/diagnóstico por imagem , Rádio (Anatomia)/diagnóstico por imagem , Vértebras Torácicas/diagnóstico por imagem , Tíbia/diagnóstico por imagemRESUMO
An analysis of the radiological appearances in a skeletal survey of 61 patients in Jamaica with homozygous sickle cell disease is presented. Evidence of bone-marrow expansion was present in all age groups. Bone infarction was shown to become increasingly common with age. Bone infarction was commonest in the femoral and humeral heads. (AU)
Assuntos
Anemia Falciforme/diagnóstico por imagemRESUMO
An analysis of the radiological appearances in a skeletal survey of 48 patients in Jamaica with sickle cell beta thalassaemia is presented. The appearances are similar to those in homozygous sickle cell disease and SC disease and a confident distinction between the conditions on radiological grounds alone is likely. (AU)