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1.
Clin Ter ; 163(1): e19-21, 2012.
Artigo em Italiano | MEDLINE | ID: mdl-22362239

RESUMO

Myocarditis seems to be mostly caused by a viral infection or more rarely by a pharmacological hypersensitivity or by radiations exposure. Nevertheless, it is not so easy to know the ethiopathogenesis of the myocarditis, because mostly it is impossible to determine the infectious agent that causes the pathology even if it is isolated. The diagnosis could often remain uncertain, so a suspect of myocarditis has to be opportunely confirmed by specific serological and diagnostic investigations, in order to avoid the appearance of a dilated cardiomyopathy which is one of its principal sequences.


Assuntos
Dor no Peito/etiologia , Infecções por Coxsackievirus/complicações , Infecções por Citomegalovirus/complicações , Infecções por Vírus Epstein-Barr/complicações , Miocardite/complicações , Anticorpos Antivirais/sangue , Autoanticorpos/biossíntese , Cardiomiopatia Dilatada/diagnóstico , Infecções por Coxsackievirus/diagnóstico , Citocinas/metabolismo , Citomegalovirus/imunologia , Infecções por Citomegalovirus/diagnóstico , Diagnóstico Diferencial , Enterovirus Humano B/imunologia , Infecções por Vírus Epstein-Barr/diagnóstico , Herpesvirus Humano 4/imunologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Insuficiência da Valva Mitral/complicações , Pericardite/diagnóstico , Insuficiência da Valva Tricúspide/complicações , Disfunção Ventricular Esquerda/complicações , Disfunção Ventricular Esquerda/fisiopatologia
2.
Clin Ter ; 163(6): 463-6, 2012 Nov.
Artigo em Italiano | MEDLINE | ID: mdl-23306738

RESUMO

Atrial fibrillation is frequently observed in Fist Aid. A rare cause is myotonic dystrophy There are two forms: Steinert's dystrophy caused by a defect of a gene myotoninaprotein kinase and Promm secondary to a defect of a Zinc Finger Protein Gene Clinical manifestations are localized in skeletal and face muscles, vitreous body, sexual glands, endocrine system, smooth muscle, central nervous system and myocardium. Sometimes, in mild and unrecognized forms of this rare disease there are arrhythmias as atrial fibrillation. We report the clinical case of a 52 year-old man, with a suspect diagnosis of Steinert's dystrophy, admitted to the emergency room for a persistent atrial fibrillation. The patient begins oral anticoagulation therapy. The patient perform a transesophageal echocardiogram before the electrical cardioversion with reset to sinus rhythm. In conclusion, with improving the screening methods of patients with primary and secondary myopathies, it has been seen an increase of cases in which a cardiac involvement occurred before or after the onset of the neuromuscular disorders. One of the most frequent alterations is represented by atrial fibrillation, responsible for an increased risk of cerebral embolism, with absolute indication for oral anticoagulation therapy. The myopathy more frequently associated with atrial fibrillation, is myotonic dystrophy, although the risk of cerebral embolism in these patients does not appear to be higher than the general population. The present case report is a spur to perform the diagnosis of Steinert disease in cases admitted to an Emergency Room because of arrhytmias, because of the possibility to perform fast and reliable specific genetic tests. A similar praxis confers to these Units an even more diagnostic clinical role.


Assuntos
Distrofia Miotônica/diagnóstico , Emergências , Serviço Hospitalar de Emergência , Humanos , Masculino , Pessoa de Meia-Idade
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