Clinical care pathway for the evaluation of patients with suspected VITT after ChAdOx1 nCoV-19 vaccination.

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare complication after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adenoviral vector vaccination. In British Columbia (BC), Canada, a provincial clinical care pathway was developed to guide clinicians in evaluating for VITT among patients who present with thrombocytopenia or thrombosis symptoms within 4 to 28 days after adenoviral vector vaccine exposure. All patients had enzyme-linked immunosorbent assay (ELISA) testing for platelet factor 4 (PF4) antibodies, and all cases with positive PF4-ELISA or d-dimer levels ≥2.0 mg/L fibrinogen equivalent units (FEU) had further testing for platelet-activating PF4 antibodies using a modified serotonin release assay (SRA). Between 1 May and 30 June 2021, 37% of 68 patients investigated for VITT had thrombosis, but only 3 had VITT confirmed by PF4-ELISA and SRA. Platelet counts, d-dimer levels, and ELISA optical density values were significantly different between those with and without VITT. Three patients had thrombocytopenia and thrombosis with d-dimer levels >4.0 mg/L FEU but had negative PF4-ELISA and SRA results. Patients with VITT were treated successfully with IV immunoglobulin, nonheparin anticoagulants, and corticosteroids. Our pathway demonstrated that thrombosis is common among patients investigated for VITT and that PF4-ELISA testing is necessary to confirm VITT in those presenting with thrombosis and thrombocytopenia.

Use of personal mobile devices to record patient data by Canadian emergency physicians and residents.

OBJECTIVE: Use of personal mobile devices to record patient data appears to be increasing, but remains poorly studied. We sought to determine the extent and reasons that Canadian emergency physicians (EPs) and emergency medicine residents use personal mobile devices to record patient data in the emergency department (ED). METHODS: A national survey was distributed to Canadian EPs and residents between 27/02/17 and 23/03/17. This captured demographics, frequency, and purpose of personal mobile device use to record patient data in the ED. It also asked about obtaining consent, security of information, implications for patient care, and knowledge of relevant regulations. RESULTS: The response rate was 23.1% (406 participants). A third (31.5%) reported using personal mobile devices to record patient data. Most (78.1%) did so more than once a month, and 7.0% did so every shift. Reasons cited included beliefs that using personal mobile devices to record patient data improves care by consultants (36.7%), expedites care (31.3%), and advances medical education (32.8%). Consent was rarely or never documented and a minority of participants (10.9%) indicated they did not obtain consent. More than half of participants (53.2%) reported being unaware of applicable regulations. CONCLUSIONS: This is the first Canadian study on the use of personal mobile devices to record patient data in the ED. Our findings demonstrate current practice may risk privacy breaches. Personal mobile device use to record patient data in the ED is common and Canadian EPs and residents believe that this practice enhances patient care.

OBJECTIF: L'utilisation des appareils mobiles personnels (AMP) pour l'enregistrement de données sur les malades semble de plus en plus fréquente, mais elle a été peu examinée jusqu'à maintenant. Aussi l'étude visait-elle à déterminer l'étendue de la pratique et les raisons pour lesquelles les médecins d'urgence (MU) et les résidents dans le domaine, au Canada, utilisent les AMP pour enregistrer des données sur les malades au service des urgences (SU). MÉTHODE: Un questionnaire d'enquête nationale a été envoyé au MU et aux résidents en la matière, au Canada, entre le 2 février 2017 et le 23 mars 2017. On a ainsi recueilli des données démographiques, de même que des renseignements sur la fréquence de la pratique et les raisons motivant l'utilisation des AMP pour la collecte de données sur les malades au SU. Des questions portaient aussi sur l'obtention du consentement, la sécurité de l'information, la portée de l'acte sur les soins aux malades et la connaissance de la réglementation applicable. RÉSULTATS: Le taux de réponse a atteint 23,1% (406 participants). Un tiers (31,5%) des répondants ont indiqué faire usage d'AMP pour enregistrer des données sur les malades. La plupart (78,1%) les utilisaient plus d'une fois par mois et 7,0%, à toutes les périodes de travail. Les raisons invoquées le plus souvent comprenaient l'opinion selon laquelle l'utilisation des AMP pour l'enregistrement de données sur les malades améliorait les soins par les consultants (36,7%), accélérait la prestation de soins (31,3%) et faisait progresser la formation médicale (32,8%). Le consentement était rarement documenté, voire jamais, et une minorité de répondants (10,9%) ont indiqué ne pas avoir obtenu le consentement des patients. Plus de la moitié des participants (53,2%) ont déclaré ne pas être courant de l'existence de règlements applicables. CONCLUSION: Il s'agit là de la première étude sur l'utilisation des AMP au Canada pour l'enregistrement de données sur les malades au SU. D'après les résultats de l'enquête, la pratique pourrait comporter des risques d'atteinte à la vie privée. L'usage des AMP pour l'enregistrement de données sur les malades au SU est courant, et les MU comme les résidents sont d'avis que la pratique améliore les soins aux malades.

Pediatric Falls: Are Monkey Bars Bad News?

Background Falls are a leading cause of childhood trauma and are the most common mechanism of injury seen in the emergency department (ED). Playground injuries represent a significant fraction of these falls. Objectives This study aims to compare the frequencies of fractures from monkey bars to other types of falls and to explore the statistical associations between the types of injuries. Methods We conducted a cross-sectional study through a retrospective chart review of all British Columbia Children's Hospital ED visits between March 2011 and February 2012. We manually extracted data from ED visits for falls in children two to 17 years of age and used descriptive statistics to report the frequencies of injuries and outcomes. We conducted multivariate logistic regression analyses to compare the odds of fractures associated with various types of falls. Results We reviewed 43,579 ED visits, of which 3,184 (7.3%) were falls. The most common types were from a standing height (42.5%), falls at home (16.2%), and at the playground (14.3%). Peaking in school-age children, these falls resulted in a diagnosis of fracture (37.3%), soft tissue contusion (20.1%), laceration/abrasion (19.4%), and minor head injury (15.8%). We identified 151 falls from monkey bars, among which 64.2% resulted in a fracture. The odds of a fracture following a fall from monkey bars was 3.1 times that of falls from all other causes. Conclusions ED physicians should have a higher suspicion for a diagnosis of fracture if a child reportedly fell from monkey bars. It is warranted to educate parents and educators on the risks associated with the play on these climbing structures.

The use of free online educational resources by Canadian emergency medicine residents and program directors.

UNLABELLED: Introduction Online educational resources (OERs) are increasingly available for emergency medicine (EM) education. This study describes and compares the use of free OERs by the Royal College of Physicians and Surgeons of Canada (RCPSC) EM residents and program directors (PDs) and investigates the relationship between the use of OERs and peer-reviewed literature. METHODS: A bilingual, online survey was distributed to RCPSC-EM residents and PDs using a modified Dillman method. The chi-square test and Fisher's exact test were used to compare the responses of residents and PDs. RESULTS: The survey was completed by 214/350 (61%) residents and 11/14 (79%) PDs. Free OERs were used by residents most frequently for general EM education (99.5%), procedural skills training (96%), and learning to interpret diagnostic tests (92%). OER modalities used most frequently included wikis (95%), file-sharing websites (95%), e-textbooks (94%), and podcasts (91%). Residents used wikis, podcasts, vodcasts, and file-sharing websites significantly more frequently than PDs. Relative to PDs, residents found entertainment value to be more important for choosing OERs (p<0.01). Some residents (23%) did not feel that literature references were important, whereas all PDs did. Both groups reported that OERs increased the amount of peer-reviewed literature (75% and 60%, respectively) that they read. CONCLUSIONS: EM residents make extensive use of OERs and differ from their PDs in the importance that they place on their entertainment value and incorporation of peer-reviewed references. OERs may increase the use of peer-reviewed literature in both groups. Given the prevalence of OER use for core educational goals among RCPSC-EM trainees, future efforts to facilitate critical appraisal and appropriate resource selection are warranted.

Extracorporeal membrane oxygenation after protracted ventricular fibrillation cardiac arrest: case report and discussion.

Extracorporeal membrane oxygenation (ECMO) is a method to provide temporary cardiac and respiratory support to critically ill patients. In recent years, the role of ECMO in emergency departments (EDs) for select adults has increased. We present the dramatic case of a 29-year-old man who was placed on venoarterial ECMO for cardiogenic shock and respiratory failure following collapse and protracted ventricular fibrillation cardiac arrest in our ED. Resuscitation efforts prior to ECMO commencement included 49 minutes of virtually continuous cardiopulmonary resuscitation (CPR), 11 defibrillations, administration of numerous medications, including a thrombolytic agent, while CPR was ongoing, percutaneous coronary intervention and stenting for a mid-left anterior descending coronary artery dissection and thrombotic occlusion, inotropic support, and intra-aortic balloon pump counterpulsation. Over the next 48 hours following ECMO commencement, the patient's cardiorespiratory function rapidly improved, and he was discharged home 9 days after admission with no neurologic sequelae. The history, indications, and increasing role of ECMO in a range of conditions, including cardiac arrest, are reviewed.

An unusual presentation of a massive pulmonary embolism with misleading investigation results treated with tenecteplase.

Background. There is no foolproof strategy to identify a pulmonary embolism (PE) in the emergency department, and atypical presentations are common. Negative test results may mislead physicians away from the diagnosis of PE. Objectives. The current report aims to raise awareness of an unusual presentation of massive PE and its diagnosis and management, in the face of limited evidence in the scientific literature. Case Reports. We report the case of a patient with a negative D-Dimer and a negative Computed Tomography contrast angiography of the chest who was diagnosed twenty-seven hours later with a massive PE, as suggested by a bedside echocardiography. The patient was successfully treated with tenecteplase (TNK). Conclusions/Summary. Pulmonary embolism frequently presents atypically and is often a diagnostic challenge. There is limited literature about the treatment of massive PE. Further research on bedside echocardiography for diagnosing PE in unstable patients is warranted. In addition, further study into new thrombolytic agents like tenecteplase in the context of massive and submassive PE is warranted.