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Coll Antropol ; 28(2): 775-80, 2004 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15666611

RESUMO

The access of ingested sucrose into blood and urine indicates the presence of mucosal lesions in the upper gastrointestinal tract. The study involved 42 children, aged 5-15, having recurrent upper abdominal pain and 43 peers with minor extra-abdominal complaints. Sucrose in urine was determined by thin layer chromatography. The test was positive in 27 out of 42 children having recurrent abdominal pain (64.3%) and in none of the control children (chi2 = 37.6, p < 0.0001). When correlated with endoscopic findings it was falsely negative in 12 out of 38 patients with endoscopically verified lesions of the stomach or duodenum and falsely positive in 1 out of 4 without lesions. Sensitivity of the test was 68.4%, specificity 97.9%, positive predictive value 96.3%. The test cannot be used as an alternative to endoscopy, but may serve for screening of candidates for it.


Assuntos
Dor Abdominal/etiologia , Sacarose/urina , Edulcorantes/análise , Administração Oral , Adolescente , Criança , Pré-Escolar , Endoscopia Gastrointestinal , Reações Falso-Negativas , Feminino , Humanos , Masculino , Permeabilidade , Valor Preditivo dos Testes , Recidiva , Sensibilidade e Especificidade , Sacarose/administração & dosagem , Edulcorantes/administração & dosagem
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