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Med Hypotheses ; 62(3): 364-6, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-14975504

RESUMO

How against HIV - using Immunology or Genetic Engineering represents a thinking about the way how to overarch the HIV virus. Namely, by the combination of Immunological and the methods of Genetic Engineering, we could create a new nonreproducible virus which would be a competitor to real HIV for CD4 receptors. Competitors, by their affinity, would be acting in order to engage the CD4 receptors, making them nonaccessible for real HIV. But, at the same time, competitors, by their size, would be just physically covering a small deal of CD4 receptors. That way these free CD4 receptors would also be nonaccessible for real HIV, but accessible for immunomolecules, like, for an example MHC II is. That way the physiological role of CD4 receptors in immunological reactions, would be saved, and that fact would help us in our intention to expel the provirus integrated in its host CD4 lymphocite, by already known immunological mechanisms. Out of the host cell (CD4 Lymphocite) the HIV virus is very responsive for our Immune System and it would be destroyed.


Assuntos
Síndrome da Imunodeficiência Adquirida/tratamento farmacológico , Fármacos Anti-HIV/imunologia , Engenharia Genética , HIV/efeitos dos fármacos , Síndrome da Imunodeficiência Adquirida/imunologia , HIV/imunologia
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