Biventricular Takotsubo Cardiomyopathy as an Unusual Presentation of SARS-CoV-2 mRNA Vaccine-Associated Multisystemic Inflammatory Syndrome.

Biventricular takotsubo cardiomyopathy (BiTCM) is a rare entity, seldom reported. We describe a case of a female presenting with multisystemic inflammatory syndrome associated with the administration of a vaccine against coronavirus disease 2019 (COVID-19). In this particular case, the patient experienced the onset of symptoms shortly after receiving a COVID-19 vaccine. Early recognition of biventricular takotsubo cardiomyopathy and timely initiation of appropriate treatment are crucial. Prompt management includes stabilizing the patient's hemodynamic status, alleviating symptoms, and addressing any underlying causes, such as inflammation or immune-related responses. Close clinical surveillance is necessary to monitor the patient's cardiac function, assess response to treatment, and prevent potential complications.

[Spontaneus pneumomediastinum associated with exacerbation of asthma during the epidemic of influenza A H1N1: Inform of four cases]. / Neumomediastino espontáneo asociado a exacerbación del asma durante la epidemia de influenza A H1N1; informe de cuatro casos.

Spontaneus pneumomediastinum (SP) is an infrequent but usually benign pathology. Its main clinical manifestations are thoracic pain, dyspnea and subcutaneous emphysema. We describe the clinical findings of 4 SP patients, identified in the context of an A H1N1 influenza virus epidemic. All the patients were young and all of them required initial medical attention for asthma exacerbation. The most frequent symptoms and signs to detect SP were cervical pain and subcutaneous emphysema; chest radiography helped to confirm the diagnosis. Concomitant A H1N1 influenza virus infection was documented in two patients. The treatment was focused in the basic pathology; two patients were placed on oseltamivir, whereas the two others just had expectant management.