[An immunofluorescence study of the viral and inframicrobial flora of the pharynx in 0- to 5-year-old children with acute respiratory diseases]. / Etude en immunofluorescence de la flore virale et inframicrobienne du pharynx chez des enfants de 0 à 5 ans atteints d'affections respiratoires aiguës.

The pharynx viral and inframicrobial flora of 52 0-5-year-old children with acute respiratory diseases was investigated through the immunofluorescence techniques. Results showed a high positivity rate (91% to 95%), the simultaneous presence in most of the patients of two to five antigens and the dominance of parainfluenza type 3 virus. The significance of the pharyngeal flora is discussed from an immunologic point of view.

[The efficacy of Macronil in treating acute respiratory infections in children 0 to 5 years old]. / Eficienta produsului Macronil în tratarea infectiilor respiratorii acute, la copii de 0-5 ani.

The authors followed the efficiency of product Macronil in association with the usual (antibiotic and symptomatic) treatments in acute, viral respiratory infections in 62 children, 0-5 years old, admitted into hospital. Besides the usual treatment (25 cases--control group) Macronil was administered in 37 cases (experimental group). A significant improvement was found in clinical evolution (duration of disease evolution, improvement of general state, good appetite, fever duration, increase in weight) of the experimental group versus the control group. An important reduction (twice) of the pharyngeal viral population appeared in the experimental group treated with Macronil. In the control group, the viral flora, remained, practically, the same after treatment.

[Effects of treatment with Macronil on the viral population of the pharynx in 0- to 5-year-old children with acute respiratory infections]. / Etude des effets du traitement au Macronil sur la population virale pharyngienne chez des enfants âgés de 0 à 5 ans, souffrant d'infections respiratoires aiguës.

Macronil (a concentrated proteic extract from mackerel) associated to usual therapeutics (antibiotics, antipyretics, vitamins) in children aged 0-5 years, with acute respiratory infections led to a reduction of the viral pharyngeal population as detected by immunofluorescence (IF) technics. The IF positivity rate in children receiving Macronil was half as high as in controls receiving only the usual therapeutics. At the same time, the number of virus species detected in the pharynx of Macronil treated children was lower than in controls in which the viral pharyngeal population was not influenced in any way by the administered therapeutics without Macronil.

Presence of viral and inframicrobial germs detected by immunofluorescence reaction in 0-5-year-old children with acute respiratory infections.

The presence of viral and/or inframicrobial antigens was investigated by the immunofluorescence (IF) technique in exfoliated pharyngeal cells collected from 85 children aged 0-5 years, with acute infections of the upper or lower respiratory tract. Positive IF reactions were recorded in 83% of the children with bronchopneumonia, 81.8% of those with acute pharyngitis, 77.7% of those with acute upper respiratory tract infections and 66.6% of those with acute bronchitis. In 68.75% of the IF-positive cases 2-5 different antigens were simultaneously visualized. Herpes and parainfluenza virus antigens appeared to be predominant. The proportion of positive IF reactions was much lower (20%) in a control group of 20 apparently healthy children, where a single viral antigen (parainfluenza 1) was detected.

The Wolf-Hirschhorn syndrome. New endocrine data.

A little girl with the Wolf-Hirschhorn syndrome showing a characteristic essential insomnia was examined clinically, genetically and hormonally. The values of arginin-vasotocin (AVT) implied in producing paradoxical sleep were normal. The relationship between AVT and insomnia is discussed.