Towards a content agnostic computable knowledge repository for data quality assessment.

BACKGROUND AND OBJECTIVE: In recent years, several data quality conceptual frameworks have been proposed across the Data Quality and Information Quality domains towards assessment of quality of data. These frameworks are diverse, varying from simple lists of concepts to complex ontological and taxonomical representations of data quality concepts. The goal of this study is to design, develop and implement a platform agnostic computable data quality knowledge repository for data quality assessments. METHODS: We identified computable data quality concepts by performing a comprehensive literature review of articles indexed in three major bibliographic data sources. From this corpus, we extracted data quality concepts, their definitions, applicable measures, their computability and identified conceptual relationships. We used these relationships to design and develop a data quality meta-model and implemented it in a quality knowledge repository. RESULTS: We identified three primitives for programmatically performing data quality assessments: data quality concept, its definition, its measure or rule for data quality assessment, and their associations. We modeled a computable data quality meta-data repository and extended this framework to adapt, store, retrieve and automate assessment of other existing data quality assessment models. CONCLUSION: We identified research gaps in data quality literature towards automating data quality assessments methods. In this process, we designed, developed and implemented a computable data quality knowledge repository for assessing quality and characterizing data in health data repositories. We leverage this knowledge repository in a service-oriented architecture to perform scalable and reproducible framework for data quality assessments in disparate biomedical data sources.

Federating clinical data from six pediatric hospitals: process and initial results for microbiology from the PHIS+ consortium.

Microbiology study results are necessary for conducting many comparative effectiveness research studies. Unlike core laboratory test results, microbiology results have a complex structure. Federating and integrating microbiology data from six disparate electronic medical record systems is challenging and requires a team of varied skills. The PHIS+ consortium which is partnership between members of the Pediatric Research in Inpatient Settings (PRIS) network, the Children's Hospital Association and the University of Utah, have used "FURTHeR' for federating laboratory data. We present our process and initial results for federating microbiology data from six pediatric hospitals.

Federating clinical data from six pediatric hospitals: process and initial results from the PHIS+ Consortium.

Integrating clinical data with administrative data across disparate electronic medical record systems will help improve the internal and external validity of comparative effectiveness research. The Pediatric Health Information System (PHIS) currently collects administrative information from 43 pediatric hospital members of the Child Health Corporation of America (CHCA). Members of the Pediatric Research in Inpatient Settings (PRIS) network have partnered with CHCA and the University of Utah Biomedical Informatics Core to create an enhanced version of PHIS that includes clinical data. A specialized version of a data federation architecture from the University of Utah ("FURTHeR") is being developed to integrate the clinical data from the member hospitals into a common repository ("PHIS+") that is joined with the existing administrative data. We report here on our process for the first phase of federating lab data, and present initial results.