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1.
AJNR Am J Neuroradiol ; 37(11): E79, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27585703
2.
AJNR Am J Neuroradiol ; 37(5): 774-81, 2016 05.
Artigo em Inglês | MEDLINE | ID: mdl-26744445

RESUMO

Visual hallucinations are relatively uncommon presentations in medical and psychiatric clinics, where they are generally regarded as a marker of possible underlying "organic" brain disease. Thus, patients with visual hallucinations are often referred for imaging of the brain. This article presents a pragmatic approach for the radiologist reviewing such imaging. Because conditions that can present with visual hallucinations are legion, a familiarity with the features of the hallucinations themselves, which can serve as clues to the underlying cause, can be helpful in interpreting such cases. We consider the nature of visual hallucinations and the mechanisms underlying their formation. We then provide a framework to guide the search for their cause, first in terms of focal lesions along the visual pathway and then global conditions affecting >1 region.


Assuntos
Encefalopatias/diagnóstico por imagem , Encéfalo/diagnóstico por imagem , Alucinações/diagnóstico por imagem , Vias Visuais/diagnóstico por imagem , Feminino , Humanos , Masculino , Neuroimagem
3.
J Inherit Metab Dis ; 32 Suppl 1: S221-6, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19609713

RESUMO

We describe the differential presentation of schizophrenia-like psychosis in two siblings with the 'variant' biochemical presentation of adult Niemann-Pick disease type C. The male sibling presented with psychosis at age 16 years and cognitive and motor disturbance at age 25 years, whereas his elder sister, sharing the same mutation but showing less severe biochemical, neuroimaging and ocular motor parameters, presented with a similar schizophrenia-like illness with associated cognitive and motor disturbance at age 31 years. Their illness onset, course and response to treatment mirrors the sex dimorphism seen in schizophrenia, and is suggestive of an interaction between the neurobiology of their metabolic disorder and sex differences in neurodevelopment.


Assuntos
Doença de Niemann-Pick Tipo C/genética , Doença de Niemann-Pick Tipo C/psicologia , Esquizofrenia/genética , Adolescente , Adulto , Proteínas de Transporte/genética , Feminino , Humanos , Peptídeos e Proteínas de Sinalização Intracelular , Masculino , Glicoproteínas de Membrana/genética , Mutação , Proteína C1 de Niemann-Pick , Doença de Niemann-Pick Tipo C/complicações , Esquizofrenia/tratamento farmacológico , Esquizofrenia/etiologia , Psicologia do Esquizofrênico , Caracteres Sexuais , Irmãos , Adulto Jovem
4.
Br J Psychiatry ; 194(4): 298-305, 2009 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-19336778

RESUMO

BACKGROUND: Few studies have investigated the relationship between schizophrenia and frontotemporal dementia. AIMS: To investigate this relationship through a clinicopathological investigation of young-onset frontotemporal dementia and a review of the case literature. METHOD: Cases of young-onset frontotemporal dementia were identified within the local brain bank. The clinical course and pathological findings were collated. For the literature review, cases of frontotemporal dementia identified through Medline were selected according to defined criteria. The demographic, clinical, pathological and genetic characteristics of cases presenting with a psychotic illness were identified. RESULTS: In the case series, 5 of 17 patients with frontotemporal dementia had presented with a psychotic illness (schizophrenia/schizoaffective disorder n=4, bipolar disorder n=1) an average of 5 years prior to the dementia diagnosis. Patients with schizophrenia exhibited changes consistent with TDP-43 and ubiquitin-positive frontotemporal dementia. In the cases review, a third of patients aged 30 years or under and a quarter of those aged 40 years or under had been diagnosed with psychosis at presentation. CONCLUSIONS: Patients with young-onset frontotemporal dementia may be diagnosed with a psychotic illness years before the dementia diagnosis is made. These findings have implications for clinicians and for our further understanding of the neurobiology of psychotic illness.


Assuntos
Demência/patologia , Esquizofrenia/patologia , Adulto , Idade de Início , Proteínas de Ligação a DNA/genética , Demência/diagnóstico , Feminino , Humanos , Imuno-Histoquímica , Masculino , Pessoa de Meia-Idade , Mutação/genética , Análise de Regressão , Esquizofrenia/diagnóstico , Adulto Jovem , Proteínas tau/metabolismo
5.
Z Kardiol ; 88(7): 514-20, 1999 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-10467651

RESUMO

Interventional duct occlusion is increasingly performed with detachable coils. In a series of 33 patients (34 procedures), we consistently used Gianturco-coils which were the initially employed coils. They are not securable but can be implanted in a simple manner. The rate of embolization was high (28%) in the first 14 procedures; however, it declined to 5% in the last 20 patients. We modified the technique by partially blocking the duct, when necessary, with a catheter which was advanced from the pulmonary artery and by implanting up to three coils. There was only one embolization and one small residual shunt in the last 20 patients. The mean fluoroscopy time in these patients was 11.0 +/- 5.8 minutes and decreased to 7.0 +/- 3.2 minutes in the last 10 patients with successful closure. Considering our experience, we continue to recommend the use of Gianturco-coils especially in the small duct which can be closed quickly at low cost.


Assuntos
Permeabilidade do Canal Arterial/terapia , Embolização Terapêutica/instrumentação , Adolescente , Criança , Pré-Escolar , Permeabilidade do Canal Arterial/diagnóstico por imagem , Desenho de Equipamento , Feminino , Humanos , Lactente , Masculino , Polietilenotereftalatos , Radiografia , Retratamento , Resultado do Tratamento
6.
Pediatr Cardiol ; 20(1): 17-20; discussion 21, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-9861067

RESUMO

A comparison was carried out concerning maximal oxygen uptake, oxygen uptake adjustment at the onset of high-intensity exercise, and maximal blood lactate between 10 healthy prepubertal boys and 35 children after repair of cardiac malformations or after Fontan operation. Mean maximal oxygen uptake (VO2) was moderately reduced in children after repair of tetralogy of Fallot or after Mustard or Senning operations and severely reduced after Fontan operations. Conversely, mean half-time of VO2 response was moderately prolonged in children after repair of tetralogy of Fallot or after Senning and Mustard operations and considerably prolonged after Fontan operations. According to our results unfavorable kinetics of VO2 response to physical exercise are present in addition to reduced aerobic power in many of the operated children. Besides being less qualified for endurance performance, these children are also less prepared for short, high-intensity exercise.


Assuntos
Procedimentos Cirúrgicos Cardíacos , Exercício Físico/fisiologia , Consumo de Oxigênio/fisiologia , Estudos de Casos e Controles , Criança , Teste de Esforço , Tolerância ao Exercício/fisiologia , Feminino , Cardiopatias Congênitas/fisiopatologia , Cardiopatias Congênitas/cirurgia , Humanos , Masculino
7.
Z Kardiol ; 87(1): 38-40, 1998 Jan.
Artigo em Alemão | MEDLINE | ID: mdl-9531699

RESUMO

Interventional duct occlusion with the Rashkind PDA occluder has become a widespread alternative treatment to surgery. Whereas residual shunting is well-known, reopening of a completely occluded duct has been published in only 3 cases. We report another case of a young adult in whom ductal shunting reappeared after he had restarted physical exercise and sports activities soon after the occlusion procedure. Recanalization might have been due to changing of the device position without embolisation. A second Rashkind PDA occluder was successfully implanted 6 months after the first procedure with complete closure of the residual shunt.


Assuntos
Prótese Vascular/efeitos adversos , Cateterismo Cardíaco/métodos , Permeabilidade do Canal Arterial/terapia , Falha de Prótese , Adulto , Embolização Terapêutica/métodos , Humanos , Masculino , Recidiva
8.
Pediatr Cardiol ; 18(5): 328-31, 1997.
Artigo em Inglês | MEDLINE | ID: mdl-9270098

RESUMO

Immediate and medium-term experience with transcatheter closure of a secundum atrial septal defect by the "buttoned" device in seven patients is reported. Complications occurred in two patients during the procedure. In one patient with complications, the occluder was partly released in the right atrium. All efforts to correct its position were unsuccessful and caused considerable deformation of the device, which had to be removed surgically. In the other patient with complications, disconnection of the occluder and counteroccluder occurred immediately after removal of the loading wire. Both parts were retrieved by catheter. Five patients had uneventful closure of the atrial septal defect. On follow-up, however, displacement of the device towards the mitral valve was observed in two patients, which caused mitral regurgitation. Surgical removal of the device and repair of the mitral valve was necessary in both patients. Two years after the procedure, the atrial septal defect was closed completely in two of the remaining three patients and a small residual defect persisted in one patient.


Assuntos
Comunicação Interatrial/terapia , Insuficiência da Valva Mitral/etiologia , Próteses e Implantes/efeitos adversos , Adolescente , Cateterismo Cardíaco , Criança , Pré-Escolar , Humanos , Valva Mitral/cirurgia , Insuficiência da Valva Mitral/cirurgia
9.
Z Kardiol ; 84(1): 55-63, 1995 Jan.
Artigo em Alemão | MEDLINE | ID: mdl-7863716

RESUMO

In 10 patients 4-20 years of age with obstructive pulmonary vascular disease after Eisenmenger reaction pulmonary arterial and aortic pressure, pulmonary and systemic flow (Qp, Qs), and pulmonary and systemic vascular resistance (Rp, Rs) were determined before and during stepwise increasing doses of prostacyclin and nifedipine. Prostacyclin caused a significant decrease of pulmonary and systemic vascular resistance and a significant decrease of pressures in the aorta and the pulmonary artery, whereas no significant changes of hemodynamics were realized following nifedipine. The individual hemodynamic changes during prostacyclin were favorable in only two patients who demonstrated a marked decrease of Rp with no substantial change of Rs resulting in an increase in arterial oxygen saturation. In the other patients prostacyclin resulted in an adverse effect with a decrease of Rs exceeding that of Rp in 5 patients, a paradoxical increase of Rp in 1 patient, and a critical decrease of Qs with respective low central venous blood oxygen saturation and consequently low arterial oxygen saturation caused by a small right-to-left shunt in 2 patients. Nifedipine did not bring about a significant general change of hemodynamic parameters. The individual control showed no effect in 5 patients, an unfavorable effect by a decrease of Rs exceeding that of Rp in 2 patients, and a favorable net effect in only 3 patients, induced in 1 patient only after a very high dosage of nifedipine and leading to a certain increase of arterial oxygen saturation in only 1 other patient. From our results a beneficial effect of nifedipine in an average dosage on the hemodynamics of patients with Eisenmenger syndrome cannot be recognized.(ABSTRACT TRUNCATED AT 250 WORDS)


Assuntos
Complexo de Eisenmenger/tratamento farmacológico , Complexo de Eisenmenger/fisiopatologia , Epoprostenol/uso terapêutico , Hemodinâmica/efeitos dos fármacos , Nifedipino/uso terapêutico , Adolescente , Adulto , Circulação Sanguínea/efeitos dos fármacos , Pressão Sanguínea/efeitos dos fármacos , Criança , Pré-Escolar , Relação Dose-Resposta a Droga , Epoprostenol/administração & dosagem , Humanos , Masculino , Nifedipino/administração & dosagem , Oxigênio/sangue , Circulação Pulmonar/efeitos dos fármacos , Resistência Vascular/efeitos dos fármacos
10.
Am J Cardiol ; 74(2): 166-9, 1994 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-8023782

RESUMO

Cardiovascular function accounts for endurance performance and, by a rapid increase in oxygen supply at the onset of exercise, contributes to short-lasting intensive exertion prevailing in many kinds of sports activities. This study determined the time for oxygen uptake (VO2) to reach one half of its asymptotic level above rest, and the respective oxygen deficit following the onset of a constant-load exercise corresponding to 80% to 90% of the maximal oxygen uptake (VO2max) in 35 children after surgical closure of a ventricular septal defect, after corrective surgery for tetralogy of Fallot, or after the Senning, Mustard, or Fontan procedures. In addition, VO2max and maximal blood lactate were determined. The half-time of VO2 response and oxygen deficit was lowest in patients after closure of a ventricular septal defect, whereas children had the most unfavorable VO2 transient kinetics after Fontan operation or with a transannular patch after correction of tetralogy of Fallot. A negative correlation was evaluated between half-time of VO2 response and VO2max, whereas maximal blood lactate varied independently of VO2max. It is concluded that many children with decreased VO2max after cardiac surgery also have unfavorable VO2 transient kinetics. In addition to being less qualified for endurance performance, they are also less prepared for short-lasting intensive energy expenditure. Therefore, the primary aim of training in these children is to improve the economy of motion of the respective tasks.


Assuntos
Comunicação Interventricular/cirurgia , Consumo de Oxigênio/fisiologia , Esforço Físico/fisiologia , Tetralogia de Fallot/cirurgia , Transposição dos Grandes Vasos/cirurgia , Valva Tricúspide/anormalidades , Valva Tricúspide/cirurgia , Adolescente , Dióxido de Carbono/análise , Criança , Metabolismo Energético , Teste de Esforço , Feminino , Comunicação Interventricular/fisiopatologia , Humanos , Cinética , Lactatos/sangue , Masculino , Oxigênio/análise , Troca Gasosa Pulmonar/fisiologia , Respiração/fisiologia , Fatores Sexuais , Tetralogia de Fallot/fisiopatologia , Transposição dos Grandes Vasos/fisiopatologia
11.
Br Heart J ; 70(1): 88-90, 1993 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-8038006

RESUMO

A complete atrioventricular block was seen in a nine year old girl in whom an infection with Borrelia burgdorferi was confirmed by serological testing. There were no other symptoms or cutaneous manifestations of the disease. Though a rash on the right ear was later recalled by her parents. The patient was treated with high dose penicillin and orciprenaline was given intermittently. The complete heart block disappeared within four days.


Assuntos
Bloqueio Cardíaco/etiologia , Doença de Lyme/complicações , Criança , Eletrocardiografia , Feminino , Bloqueio Cardíaco/fisiopatologia , Humanos , Doença de Lyme/fisiopatologia
12.
Eur J Pediatr ; 152(3): 226-31, 1993 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-8444249

RESUMO

Recent studies have shown that in boys a steady-state of blood lactate is maintained at exercise levels above the anaerobic threshold. Therefore, the explanation hitherto provided for the steeper increase in blood lactate beyond the anaerobic threshold, i.e. the onset of anaerobic metabolism, needs modification. Investigations were carried out in ten boys, aged 11-12 years, during treadmill running. Maximal oxygen uptake (VO2max) and maximal blood lactate were determined during incremental exercise. Subsequently each boy performed four runs at different high constant speeds of 16 min duration, in order to determine maximal steady-state blood lactate. The underlying data also served to estimate roughly the lactate anaerobic threshold. Oxygen uptaken (VO2) was measured at 0.5 min intervals during the initial 7.5 min of each constant-speed run. Maximal steady-state blood lactate was 5.6 mmol/l corresponding to 92% of VO2max. The mean blood lactate at which the anaerobic threshold was reached or just exceeded was 2.7 mmol/l corresponding to 82% of VO2max. Oxygen transport transient kinetics were computed from the mean 0.5 min VO2-values during the constant-speed runs near the maximal steady-state blood lactate and from runs near the anaerobic threshold. Half-times of VO2 response were shorter than values previously reported for adults due to a faster increase in VO2 at the onset of exercise. Half-times increased with increasing work rates as did the oxygen deficit, due to a slower increase in VO2 along with a longer time required to attain a steady-state at higher work rates.(ABSTRACT TRUNCATED AT 250 WORDS)


Assuntos
Exercício Físico , Hipóxia/sangue , Lactatos/sangue , Criança , Humanos , Masculino , Consumo de Oxigênio
13.
Artigo em Inglês | MEDLINE | ID: mdl-2007397

RESUMO

To elucidate further the special nature of anaerobic threshold in children, 11 boys, mean age 12.1 years (range 11.4-12.5 years), were investigated during treadmill running. Oxygen uptake, including maximal oxygen uptake (VO2max), ventilation and the "ventilatory anaerobic threshold" were determined during incremental exercise, with determination of maximal blood lactate following exercise. Within 2 weeks following this test four runs of 16-min duration were performed at a constant speed, starting with a speed corresponding to about 75% of VO2max and increasing it during the next run by 0.5 or 1.0 km.h-1 according to the blood lactate concentrations in the previous run, in order to determine maximal steady-state blood lactate concentration. Blood lactate was determined at the end of every 4-min period. "Anaerobic threshold" was calculated from the increase in concentration of blood lactate obtained at the end of the runs at constant speed. The mean maximal steady-state blood lactate concentration was 5.0 mmol.l-1 corresponding to 88% of the aerobic power, whereas the mean value of the conventional "anaerobic threshold" was only 2.6 mmol.l-1, which corresponded to 78% of the VO2max. The correlations between the parameters of "anaerobic threshold", "ventilatory anaerobic threshold" and maximal steady-state blood lactate were only poor. Our results demonstrated that, in the children tested, the point at which a steeper increase in lactate concentrations during progressive work occurred did not correspond to the true anaerobic threshold, i.e. the exercise intensity above which a continuous increase in lactate concentration occurs at a constant exercise intensity.


Assuntos
Limiar Anaeróbio/fisiologia , Hemostasia/fisiologia , Lactatos/sangue , Criança , Exercício Físico/fisiologia , Humanos , Masculino , Consumo de Oxigênio/fisiologia , Respiração/fisiologia , Corrida , Relação Ventilação-Perfusão/fisiologia
14.
Int J Cardiol ; 29(1): 21-8, 1990 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-2262211

RESUMO

Four patients with complex cardiac lesions, who underwent successfully a Fontan type of operation are presented, each case representing a particular problem in surgical management. The first exhibited displacement of a trileaflet straddling and overriding left atrioventricular valve in addition to tricuspid atresia, while the second one had unilateral lung perfusion. In the third case, a stenosis had developed near the origin of the right pulmonary artery, and pulmonary vascular resistance could not be determined prior to the definite palliation procedure, whereas the fourth patient presented with stenosis of the left atrioventricular valve. Surgery was planned after detailed evaluation of the morphologic and hemodynamic features by means of echocardiography and cardiac catheterization. Our results illustrate the common tendency to extend the limits for modified Fontan procedures, which also includes revision of the original criteria for selection.


Assuntos
Cardiopatias Congênitas/cirurgia , Cateterismo Cardíaco , Procedimentos Cirúrgicos Cardíacos/métodos , Criança , Pré-Escolar , Angiografia Coronária , Ecocardiografia , Cardiopatias Congênitas/diagnóstico , Cardiopatias Congênitas/fisiopatologia , Humanos , Lactente , Recém-Nascido , Masculino
15.
Eur J Pediatr ; 149(11): 771-3, 1990 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-2226548

RESUMO

To evaluate whether anaerobic threshold criteria evaluated in adults are pertinent to children, ten boys with a mean age of 11.2 years were investigated during treadmill running. Maximal running velocity was determined at stepwise increasing load, with determination of blood lactate following exercise. On the following days four runs each lasting 16 min were performed at a constant speed starting with a speed corresponding to about 70% of the maximal speed and increasing it during the next run in order to determine maximal steady state levels of blood lactate. Blood lactate was measured at the end of every 4 min period. From this date the anaerobic threshold was calculated. The correlation between anaerobic threshold values and maximal steady state levels of blood lactate was poor, however, a steady state of blood lactate was present at 4.6 mmol/l, whereas the mean anaerobic threshold value was determined at 2.6 mmol/l. In view of our results, the anaerobic threshold during increasing work does not correspond to the true anaerobic threshold, which can be assumed to occur at much higher lactate values. The meaning of the term anaerobic threshold is therefore to be questioned.


Assuntos
Limiar Anaeróbio/fisiologia , Lactatos/sangue , Esforço Físico/fisiologia , Criança , Humanos , Masculino , Consumo de Oxigênio/fisiologia
16.
Int J Cardiol ; 22(2): 241-7, 1989 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-2464548

RESUMO

The "absent" pulmonary valve syndrome is associated with aneurysmal dilatation of the pulmonary trunk, stenosis of the ventriculo-arterial junction with or without malalignment of the outlet septum, and ventricular septal defect. When the outlet septum is malaligned, the morphology resembles that of tetralogy of Fallot. We report our experience with 4 infants with this syndrome. All were in severe respiratory distress and cardiac failure when first seen. Cardiac catheterization was performed at 0.5-4.5 months of age in 3 of them. In the other, the clinical and echocardiographic features were considered sufficient to establish the diagnosis. Banding of the pulmonary trunk was carried out at the age of 2.5-5 months. The distal pulmonary arterial pressure in 3 cases dropped to 12-19 mm Hg. These patients could be extubated within one week postoperatively. Their course 1-3 years later is excellent, with rare episodes of mild respiratory problems only and markedly diminished pulmonary insufficiency. One child, weighing 3250 g at surgery, whose pulmonary arterial pressure did not drop below 29 mm Hg, could not be weaned off the respirator. Corrective surgery was undertaken 17 days later, but the patient died of respiratory complications. Based on clinical and Doppler sonographic findings, on control catheterization data and on haemodynamic findings in 3 surviving infants and two further patients with an uneventful course who, as yet, have not undergone surgery, we conclude that the beneficial effect of banding is the combined result of reduced pulmonary arterial pressure and decreased pulmonic regurgitation.


Assuntos
Cuidados Paliativos/métodos , Artéria Pulmonar/cirurgia , Valva Pulmonar/anormalidades , Pré-Escolar , Seguimentos , Humanos , Lactente , Recém-Nascido , Complicações Pós-Operatórias/terapia , Insuficiência da Valva Pulmonar/cirurgia , Estenose da Valva Pulmonar/cirurgia , Pressão Propulsora Pulmonar , Síndrome do Desconforto Respiratório do Recém-Nascido/terapia , Síndrome , Tetralogia de Fallot/cirurgia
17.
Pediatr Cardiol ; 10(3): 170-3, 1989.
Artigo em Inglês | MEDLINE | ID: mdl-2798194

RESUMO

A rare type of primum atrial septal defect is described in which the atrial septum deviated to the left, resulting in a double-outlet right atrium. The obstruction at the site of the small atrial septum defect led to an elevation of the left atrial mean pressure and to pulmonary arterial hypertension. The presence of mixed blood in the right atrium caused systemic arterial desaturation. A cleft in the septal leaflet of the left atrioventricular (AV) valve caused a left ventricular-right atrial shunt, which-added to the left-to-right atrial shunt--totaled 60% of the pulmonary circulating volume. Preoperative knowledge of the anatomic features facilitated surgical repair, which consisted in resection of the abnormal septum, construction of a new septum with a Dacron patch, and closure of the septal commissure of the left-sided AV valve.


Assuntos
Cardiopatias Congênitas , Defeitos dos Septos Cardíacos , Anormalidades Múltiplas , Angiocardiografia , Cateterismo Cardíaco , Pré-Escolar , Átrios do Coração , Cardiopatias Congênitas/diagnóstico , Cardiopatias Congênitas/diagnóstico por imagem , Cardiopatias Congênitas/cirurgia , Defeitos dos Septos Cardíacos/diagnóstico , Defeitos dos Septos Cardíacos/diagnóstico por imagem , Defeitos dos Septos Cardíacos/cirurgia , Humanos , Masculino
18.
Int J Cardiol ; 19(3): 378-81, 1988 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-3397202

RESUMO

Precise preoperative diagnostic clarification was accomplished in an infant with left atrial isomerism. The inner/outer arrangement of the pulmonary/systemic veins in relation to the posterior wall of the common atrium necessitated a specific baffle in order to prevent pulmonary or systemic venous obstruction. The development of a sick sinus syndrome six months after surgery is in keeping with the natural history of the disease.


Assuntos
Cardiopatias Congênitas/cirurgia , Prótese Vascular , Dextrocardia/cirurgia , Feminino , Átrios do Coração/anormalidades , Comunicação Interatrial/cirurgia , Comunicação Interventricular/cirurgia , Humanos , Lactente , Marca-Passo Artificial , Complicações Pós-Operatórias/terapia , Veias Pulmonares/anormalidades , Veias Pulmonares/cirurgia , Síndrome do Nó Sinusal/terapia , Veias Cavas/anormalidades
19.
Monatsschr Kinderheilkd ; 136(3): 130-4, 1988 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-3374497

RESUMO

We report our results with 14 cases of tetralogy of Fallot, which were treated with a modified Blalock-Taussig shunt first, total correction having been performed in 9 of them after a mean interval of 15 months. The age of the patients ranged from 12 days to 3.3 years, with a mean of 4.7 months in 12 patients below the age of one year. In 11 cases we used a 5 mm Gore-Tex prosthesis, in 2 a 6 mm prosthesis and in one a 4 mm prosthesis. All children survived the operation. In one case shunt thrombosis occurred after a bout of pneumonia and a second shunt had to be constructed on the other side. Control angiography, performed after a mean period of 15 months in 13 patients revealed a patent shunt, though angulation of the ipsilateral pulmonary artery was noted in one case. The ratio of the diameter of the pulmonary artery to the aorta increased by 20%. The significance of these findings with regard to the question of primary or two-stage repair in infants less than one year old is discussed in view of different risk factors.


Assuntos
Anastomose Cirúrgica/métodos , Prótese Vascular , Artéria Pulmonar/cirurgia , Tetralogia de Fallot/cirurgia , Pré-Escolar , Seguimentos , Humanos , Lactente , Recém-Nascido , Complicações Pós-Operatórias/etiologia , Pressão Propulsora Pulmonar
20.
Z Kinderchir ; 42(6): 343-5, 1987 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-2964154

RESUMO

The frequent use of central venous catheters for administration of fluids and especially ventriculovenous shunts in children sometimes lead to embolisations of catheter fragments. Because of the potential complications, extraction of the fragments is mandatory. In 5 children aged 1.8 to 7.8 years fragments were removed from the right heart and the pulmonary artery by use of a loop snare, a helical basket or a myocardial biopsy catheter. In four cases the fragment was the distal part of a ventriculoatrial shunt, in one case the central part of a silastic catheter had accidentally advanced into the pulmonary artery. In two cases adhesions of the fragment to the wall of the pulmonary artery impeded the extraction.


Assuntos
Angioplastia com Balão/instrumentação , Cateteres de Demora , Embolia/terapia , Corpos Estranhos/terapia , Átrios do Coração , Veia Cava Superior , Criança , Pré-Escolar , Feminino , Migração de Corpo Estranho/terapia , Humanos , Lactente , Masculino , Artéria Pulmonar , Embolia Pulmonar/terapia
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