[Physical rehabilitation of inpatients with ischemic heart disease].

In modern physical rehabilitation of IHD patients the main tendencies are early activation and elaboration of new safe programs of physical trainings (PhT) improving the hemodynamic indices and increasing physical rehabilitation (PhR) of patients. The aim of the present study was to investigate the effect of bicycle exercise (BE) in the free-load bicycle exercise (FBE) on central hemodynamics and PhR of inpatients with different clinical forms of IHD. 185 patients (99 males and 86 females) aged 46-76 years (mean age of 68.4 +/- 1.6 years), with different clinical forms of IHD, were been examined. The inclusion of IHD cases into complex management is been followed by significant improvement of cardiac pump function--increase of stroke index, ejection fraction (EF) and rise in PhR in all clinical groups. The use of traditional therapy only in management is been followed by merely significant rise in EF (mean--by 19%) and total amount of performed work and microcirculation indices in patients with paroxysmal arrhythmia and stenocardia, less evident than in use of FBE. The absence of complications in our patients permit to recommend the application of this method in IHD inpatients.

[Physical exercises in rehabilitation of patients with coronary heart disease at in-patient stage].

The main directions of state-of-the-art physical rehabilitation of patients with coronary heart disease (CHD) are early activation and development of new harmless programs of physical training (PT), improving indices of central hemodynamics and physical efficiency (PE) of patients. The purpose of the work is to study how bicycle training (BT) by the method of free choice of load (FCL) influence on central hemodynamics and PE of patients with various clinical forms of CHD at in-patient stage of physical rehabilitation. 185 patients with various forms of CHD at the age from 46 to 76 years (average age 68.4 +/- 1.6 years), 99 males and 86 females, were examined. Including of BT by the method of FCL in combined treatment of CHD patients was accompanied by significant improvement of heart pumping ability: increase in beat index, ejection fraction and PE in all clinical groups. Use only traditional therapy leaded to significant improvement only of ejection fraction, volume of performed work and threshold power in patients with paroxysmal atrial fibrillation and angina, but less expressive than with the use of BT. Absence of complication in our patients during treatment makes possible to recommend use of the method for CHD patients at in-patients stage of medical rehabilitation.

[Lipid peroxidation and antioxidant defense in patients with ischemic heart disease: correction with free-load bicycle exercise].

AIM: To study changes in lipid peroxidation-antioxidant defense (LPO-AOD) system in patients with various clinical forms of ischemic heart disease (IHD) in response to free-load bicycle exercise (FBE). MATERIAL AND METHODS: A total of 185 IHD patients aged 46-76 years (mean age 68.4 +/- 1.6 years, 99 males and 86 females) were randomized into two groups. Group 1 consisted of 90 patients who received standard medication and FBE. Group 2 of 95 patients received only standard medication. Thirty four healthy controls entered the control group. Each group was divided into subgroups by a clinical form of IHD. LPO was assessed by plasma levels of lipid peroxide (LP), malonic dialdehyde (MDA), AOD--by total antioxidant activity (TAA) in plasma red cells, activity of superoxide dismutase (SOD) and catalase in red cells. RESULTS: Irrespective of a clinical form of IHD, conventional therapy stimulated AOD and decreased LP by 15.1% (p < 0.05), MDA by 21.4% (p < 0.05), on the average, but still these parameters were higher than in healthy controls. The addition of FBE reduced AOD to the levels of that of healthy controls, enhanced AOD the activation of which depended on a clinical form of IHD. CONCLUSION: FBE elevates antiradical potential of blood in trained patients with different clinical forms of IHD. The highest effect was observed on enzymatic link of the AOD system.

[Bicycle exercise in the free load regimen and hemodynamics in inpatients with ischemic heart disease].

Hypokinesia is not an independent risk factor of ischemic heart disease (IHD) but it contributes to progression of this disease because of a positive correlation with such risk factors as arterial hypertension, dislipoproteinemia, obesity, hyperinsulinism, diabetes mellitus type 2. This dictates the necessity to add exercise to pharmacotherapy of IHD. Combined treatment of IHD including bicycle exercise in the free load regimen significantly improves cardiac pump function--a 32.0 and 34.7% mean rise in stroke index and ejection fraction in patients under 60 years of age, respectively. The above rise does not depend on the initial condition of hemodynamics. There are cases when the increase is the highest in patients with the least baseline indices showing the presence of adaptive reserves which realize in physical training. The patients treated had no complications. Thus, use of the above bicycle exercise in IHD patients can be recommended for hospital rehabilitation.

[Combined therapy of interstitial cystitis using the "Aeltis-Synchro-02-Iarilo" device]. / Kompleksnaia terapiia interstitsial'nogo tsistita s primeneniem apparata "Aéltis-Sinkhro-02-Iarilo".

Multiple modality therapy of interstitial cystitis (IC)--the disease characterized by nicturia, pelvic pains, imperative pollakiuria--is considered. As IC nature is not well known, its treatment remains empiric. Among the underlying causes, most probable are autoimmune, allergic, infectious, neurological, vascular. Therefore, the treatment should be multi-modality. Most usable now is combined chemotherapy. Perspective is also IC treatment with medicines in combination with physiotherapy (electromagnetolaser AELTIS-SYNCHRO-02-YARILO"). Endovesical electrophoresis can be also applied.

[Lipid peroxidation in patients with gastric and duodenal peptic ulcers]. / Sostoianie perekisnogo okisleniia u bol'nykh s iazvennoi bolezn'iu zheludka i dvenadtsatiperstnoi kishki.

The oxidant and antioxidant status of 42 patients with pyloroduodenal ulcers aged 17-46 years was examined before and after traditional hospital treatment. Total oxidative activity and plasma concentrations of lipid hydroperoxides and malonic dialdehydes were higher in the patients before therapy than in the controls, this increase correlating with the disease duration. Total antioxidative activity and catalase of erythrocytes were decreased only in the patients with ulcer relapses, whereas in the patients with primary ulcers, these values were virtually normal. Erythrocyte superoxide dismutase activity was reduced in all the patients. Low activity of this enzyme negatively correlated with the disease duration. The treatment led to evident clinical and endoscopic improvement but did not completely normalize the increased level of free-radical oxidation parameters and decreased total antioxidative activity and erythrocyte catalase and superoxide dismutase activities.

[The effect of combined treatment using bicycle exercise with a free choice of the load parameters on the hemodynamics in peptic ulcer patients]. / Vliianie kompleksnogo lecheniia s primeneniem velotrenirovok so svobodnym vyborom parametrov nagruzki na gemodinamiku bol'nykh iazvennoi bolezn'iu.

AIM: To study the role of bicycle exercise in combined treatment of gastric and duodenal ulcer, its effect on central hemodynamics and microcirculation. MATERIALS AND METHODS: 94 patients with gastric and duodenal ulcer. 64 patients received conventional antiulcer treatment plus exercised on bicycle ergometer in free regimen of training. 30 patients on the routine treatment only served as control. RESULTS: Doppler echocardiography demonstrated that ulcer patients have eukinetic hemodynamic type more frequently. After combined treatment with bicycle exercise hyper- and hypokinetic hemodynamic types transformed into the eukinetic one, while the eukinetic type remained unchanged. Bicycle exercise contributed to normalization of microcirculation (as shown by conjunctival biomicroscopy), especially in location of ulcer in the duodenum. CONCLUSION: Introduction of bicycle exercise in the treatment of ulcer promoted acceleration of ulcer defects healing, especially in patients with hyperkinetic hemodynamics and duodenal ulcer.

[Actinic reticuloid]. / Aktinicheskii retikuloid.

A patient with a rare dermatosis, actinic reticuloid, is described. Differential diagnostic characteristics of this condition as against mycosis fungoides are presented, and rational therapy of such patients is discussed.

[The connection of Hebra's herpetiform impetigo to pustular psoriasis]. / Ob otnoshenii gerpetiformnogo impetigo Gebry k pustuleznomu psoriazu.

Two clinical cases of Hebra's impetigo herpetiformis are described. This rare dermatosis is regarded as a variant of pustular psoriasis and is difficult for differential diagnosis.