User-centered design and usability testing of an innovative health-related quality of life module.

OBJECTIVES: Various computerized health risk appraisals (HRAs) are available, but few of them assess health-related quality of life (HRQoL) in a goal-directed framework. This study describes the user-centered development and usability testing of an innovative HRQoL module that extends a validated HRA tool in primary care settings. METHODS: Systematic user-centered design, usability testing, and qualitative methods were used to develop the HRQoL module in primary care practices. Twenty two patients and 5 clinicians participated in two rounds of interactive technology think-out-loud sessions (TOLs) and semi-structured interviews (SSIs) to iteratively develop a four-step, computerized process that collects information on patient goals for meaningful life activities and current level of disability and presents a personalized and prioritized list of preventive recommendations linked to online resources. RESULTS: Analysis of TOLs and SSIs generated 5 categories and 11 sub-categories related to facilitators and barriers to usability and human-technology interaction. The categories included: Understanding the Purpose, Usability, Perceived Value, Literacy, and Participant Motivation. Some categories were inter-connected. The technology was continually and iteratively improved between sessions until saturation of positive feedback was achieved in 4 categories (addressing motivation will require more research). Usability of all screen units of the module was improved substantially. Clinician feedback emphasized the importance of the module's ability to translate the patient-centered HRQoL Report into actionable items for clinicians to facilitate shared decision-making. Complete integration of the HRQoL module into the existing HRA will require further development and testing. CONCLUSIONS: Systematic application of user-centered design and human factors principles in technology development and testing may significantly improve the usability and clinical value of health information systems. This more sophisticated approach helped us translate complex clinical concepts, goal-setting steps, and decision-support processes into an accepted and value-added technology.

Novel computerized health risk appraisal may improve longitudinal health and wellness in primary care: a pilot study.

OBJECTIVES: Health Risk Appraisals (HRAs) have been implemented in a variety of settings, however few studies have examined the impact of computerized HRAs systematically in primary care. The study aimed at the development and pilot testing of a novel, comprehensive HRA tool in primary care practices. METHODS: We designed, implemented and pilot tested a novel, web-based HRA tool in four pair-matched intervention and control primary care practices (N = 200). Outcomes were measured before and 12 months after the intervention using the HRA, patient surveys, and qualitative feedback. Intervention patients received detailed feedback from the HRA and they were encouraged to discuss the HRA report at their next wellness visit in order to develop a personalized wellness plan. RESULTS: Estimated life expectancy and its derivatives, including Real Age and Wellness Score were significantly impacted by the HRA implementation (P<0.001). The overall rate of 10 preventive maneuvers improved by 4.2% in the intervention group vs. control (P = 0.001). The HRA improved the patient-centeredness of care, measured by the CAHPS PCC-10 survey (P = 0.05). HRA use was strongly associated with better self-rated overall health (OR = 4.94; 95% CI, 3.85-6.36) and improved up-to-dateness for preventive services (OR = 1.22; 95% CI, 1.12-1.32). A generalized linear model suggested that increase in Wellness Score was associated with improvements in patient-centeredness of care, up-to-dateness for preventive services and being in the intervention group (all P<0.03). Patients were satisfied with their HRA-experience, found the HRA report relevant and motivating and thought that it increased their health awareness. Clinicians emphasized that the HRA tool helped them and their patients converge on high-impact, evidence-based preventive measures. CONCLUSIONS: Despite study limitations, results suggest that a comprehensive, web-based, and goal-directed HRA tool can improve the receipt of preventive services, patient-centeredness of care, behavioral health outcomes, and various wellness indicators in primary care settings.

Family physicians increase provision of well-infant care despite decline in prenatal services.

Over the past 20 years, family physicians and general practitioners (FP/GPs) and pediatricians have upheld their commitment to preventive care for infants. Non-Metropolitan Statistical Areas (non-MSAs) depend on family physicians for almost one half of their well-infant care. FP/GPs have increased their overall provision of well-infant care despite a decline in delivery of prenatal services. This commitment to child health care demands continued excellence of family physician training in pediatric medicine, preventive care, and child advocacy.

Diagnosing influenza: the value of clinical clues and laboratory tests.

OBJECTIVE: Our goal was to determine the utility of clinical clues, white blood cell (WBC) and differential counts, and a rapid antigen test for differentiating influenza from coexistent infectious diseases during influenza epidemics. STUDY DESIGN: Data were collected during 3 consecutive influenza outbreaks over a 2-year period. The information collected included date of onset, symptoms, vaccine status, WBC and differential counts, ZstatFlu test (ZymeTx, Oklahoma City, Ok), and influenza culture. Using culture positivity as the criterion for influenza diagnosis, we compared cases with noncases on each variable independently and by logistic regression. Receiver operating characteristic curves were plotted for WBC count, ZstatFlu, and their combination in an effort to determine the most useful diagnostic strategy. POPULATION: We included consecutive patients presenting to a family practice office with fever, cough, sore throat, myalgia, and/or headache during flu season. OUTCOMES MEASURED: The outcomes were sensitivity, specificity, and other measures of test accuracy. RESULTS: Culture-positive cases could not be reliably distinguished from those that were culture negative using symptoms or vaccination status. Both WBC count and ZstatFlu results discriminated fairly well, and their combination did somewhat better. Differential counts were not helpful. WBC counts above 8000 were associated with a low probability of influenza. The sensitivity and specificity of the ZstatFlu were 65% and 83%, respectively. CONCLUSIONS: Our data suggest that symptoms and vaccine status do not reliably identify patients with influenza. Use of WBC counts and the ZstatFlu test can be helpful. The sequence, combination, and criteria for use of these tests depend on tradeoffs between undertreatment of influenza cases and the overtreatment of noninfluenza cases, and the cost and benefit projections for individual patients.

Relational value: bridging the worldview gap between patients and health systems.

Since its inception, family medicine has understood the importance of a holistic approach to health care and the benefits stemmingfrom integrating health care resources. This approach and its benefits have not, however, been fully appreciated by consumers, payers, and policy makers, especially in today's dynamic marketplace. Articulating the benefits of an integrated approach is more likely to be effective if done in the language of the marketplace and in a framework that helps them understand the critical importance of relationships that are needed for integrating consumers' needs with resources in systems. By using the concept of "value" recognized within the marketplace, this article creates a new framework for visualizing integration and relationships. It then embodies the benefits within a new term called relational value. With this concept and terminology, primary care physicians should be able to more effectively communicate to administrators and policy makers the added value of a holistic approach. Lastly, two ideas for creating relational value are discussed to help point the way to new health care delivery models.

Perceived needs of African-American caregivers of elders with dementia.

To assess the perceived needs of African-American caregivers and their expectations of the health care system, perceived level of success and satisfaction in meeting their needs, and their level of distress, we convened two focus groups at a local church in Oklahoma City, OK to discuss three questions. Responses were qualitatively analyzed for common themes. The groups comprised 13 African-American caregivers of demented elders. All participants completed a demographic form, the Zarit Burden Interview, and the Depression Scale. We found that African-American caregivers are frustrated with health care and service providers. The main differences of this group compared with other caregivers were their perceptions of racism and the absence of an available local support group. This information can serve to guide future studies in developing ways to increase caregiver satisfaction, decrease caregiver stress, and increase patient quality of life for this subgroup of caregivers.

Management of laboratory test results in family practice. An OKPRN study. Oklahoma Physicians Resource/Research Network.

BACKGROUND: Ineffective management of laboratory test results can result in suboptimal care and malpractice liability. However, there is little information available on how to do this important task properly in primary care settings. METHODS: We used a questionnaire guided by a literature review to identify a conceptual model, current practices, and clinicians who reported having an effective method for at least one of 4 steps in the process of managing laboratory test results. Clinicians with differing methods were selected for each of the steps. Practice audits and patient surveys were used to determine actual performance. On the basis of these audits, we constructed a unified best method and conducted time-motion studies to determine its cost. RESULTS: After auditing only 4 practices we were able to identify effective methods for 3 of the 4 steps involved in the management of laboratory test results. The unified best method costs approximately $5.19 per set of tests for an individual patient. CONCLUSIONS: By identifying effective practices within a family practice research network, an effective method was identified for 3 of the 4 steps involved in the management of laboratory test results in primary care settings.

The effect of labeling on perceived ability to recover from acute illnesses and injuries.

BACKGROUND: The process of giving a patient a diagnosis may cause harm. The adverse effects of labeling, best documented for the diagnosis of hypertension, include increased absenteeism from work and lower earnings, increased depressive symptoms, and reduced quality of life. We tried to determine whether the diagnosis of hypertension affects perceptions about the time required to recover from common acute medical problems. METHODS: In an academic family practice clinic, equal numbers of patients with and without hypertension were asked to estimate how long it would take them to recover from an upper respiratory tract infection (URI), a urinary tract infection (UTI), and an ankle sprain now and 5 years ago (before the diagnosis of hypertension). RESULTS: Compared with patients who did not have hypertension, patients with hypertension estimated that it would take them twice as long, on average, to recover from a URI now (11.7 vs 6.0 days, P=.002) and in the past (10 vs 5.5 days, P=.02). These differences persisted after controlling for age, sex, race, and education. No significant differences were found for estimated recovery times for UTI or ankle sprain. CONCLUSIONS: The diagnosis of hypertension may affect patients' perceptions of their ability to recover from unrelated acute illnesses. This may have implications for the way physicians choose to present information to patients.

The clinical characteristics of brown recluse spider bites treated by family physicians: an OKPRN Study. Oklahoma Physicians Research Network.

BACKGROUND: The brown recluse spider (Loxosceles reclusa) has been recognized as a cause of necrotizing bites since at least 1957, but most of the literature consists of laboratory studies using animals, human sera, or case reports of more dramatic examples of bite reactions. Our goal was to develop a more comprehensive clinical description of the brown recluse spider bites treated by family physicians. METHODS: Two preprinted, postage-paid cards were given to physician members of the Oklahoma Physicians Research Network. One card was used for recording examination and treatment data, and the other was for tracking the progress of the bite until it was completely healed. For comparison, similar information was collected from the local poison control center. RESULTS: From April 1996 to August 1998, the physicians recorded 149 bites. Most of the victims were women aged 18 to 65 years, and most sought treatment within 3 days. Pain was common but not universal. Most bites were located on the extremities. Erythema was always present, but necrosis was present in only 40% of the bites. Some systemic signs or symptoms were common. The most frequent forms of treatment were systemic antibiotics (66% of cases) and conservative wound management (56%). Only 1 hospitalization occurred; 43% of the bites healed within 2 weeks; and only 13% resulted in scarring. CONCLUSIONS: The brown recluse spider bite is a relatively common problem treated by family physicians in Oklahoma. Most bites are not serious. More research at the practice level is needed to develop diagnostic criteria and to explore the effectiveness of various treatment options.

The lack of association between hypertension and hypothyroidism in a primary care setting.

This work examines the association between hypertension and hypothyroidism in geriatric patients seen at a primary care medical office. One hundred and twenty-two geriatric patients with elevated thyroid stimulating hormone (TSH) levels were selected for the study. An equal number of euthyroid geriatric individuals were selected from the same clinic for comparison. We found no differences in mean diastolic blood pressure (DBP) in the euthyroid and hypothyroid groups (80.1 mm Hg vs 78.9 mm Hg, P = 0.25). Additionally, there was no significant association between having hypertension (defined as having an elevated DBP or receiving treatment for hypertension at the time of the index visit) and level of TSH (P = 0.33). Logistic regression did show that race, gender, body mass index and renal function were significantly associated with the presence of hypertension. Lastly, there was not a significant association between level of TSH and DBP as determined by regression (P = 0.97). In conclusion, in this population of geriatric patients we did not find hypertension to be associated with the presence of hypothyroidism.

Patient-physician E-mail communication.

A significant number of Oklahomans are using computers and have e-mail access either at home or at work. Consecutive patients seen by 23 family physician members of the Oklahoma Physicians Research/Resource Network (OKPRN) were queried regarding their use of computers and access to e-mail. The numbers are higher in urban and suburban areas than in medium and smaller towns and rural areas. Of those who have e-mail access now or are planning to get it within six months, a substantial majority would like to use this medium to interact with their family physician. Potential uses for e-mail technology and problems to be overcome are discussed.

Outcomes of an insurance company-sponsored multichannel chemistry screening initiative.

BACKGROUND: The use of serum chemistry panels as screening tests has been studied in a variety of clinical and nonclinical settings. None of the studies, however, has attempted to carefully examine any potential harm done to participants, and none has measured the impact on health-related quality of life. METHODS: Consenting participants in an insurance company-sponsored screening initiative completed a questionnaire before and 6 months after having blood drawn for a 25-item chemistry panel and a lipid profile; for men older than 50, a prostate-specific antigen (PSA) test was also done. The prescreening questionnaire included demographic and health information. The postscreening questionnaire included questions about specific outcomes. Included in both questionnaires were single-item measures of self-rated health and self-rated worry about health, and the 17-item Duke Health Profile (DUKE), a measure of health-related quality of life. Various outcomes were examined, including the numbers of new diagnoses, numbers and types of new treatment recommendations, change in self-reported health and worry, and change in DUKE subscale scores. Participants who were potentially helped and those who were potentially harmed by the serum chemistry panels screening program were identified and further characterized. RESULTS: Of the 2249 subjects who satisfactorily completed both questionnaires, 2012 (89%) had at least one abnormal test result, but only 985 of these (49%) remembered having discussed their test results with a physician. A total of 342 individuals received new treatment advice. However, 29 (10%) of them indicated that they would be "somewhat unlikely" to "very unlikely" to follow it. Following the intervention questionnaire, there were statistically significant average decrements in the General Health, Physical Health, and Pain subscales of the DUKE for participants with abnormal results. Self-rated health status did not change but level of worry about health increased significantly. At least 250 (11%) subjects were potentially helped by the screening initiative, but at least 574 (26%) were potentially harmed by it. CONCLUSIONS: The use of serum chemistry panels as screening tests in nonclinical settings should probably be discouraged, since health-related quality of life is not improved and the intervention may harm more individuals than it benefits.

The determination and interpretation of reference intervals for multichannel serum chemistry tests.

BACKGROUND: When interpreting the results of clinical chemistry tests, physicians rely heavily on the reference intervals provided by the laboratory. It is assumed that these reference intervals are calculated from the results of tests done on healthy individuals, and, except when noted, apply to people of both genders and any age, race, or body build. While analyzing data from a large screening project, we had reason to question these assumptions. METHODS: The results of 20 serum chemistry tests performed on 8818 members of a state health insurance plan were analyzed. Subgroups were defined according to age, race, sex, and body mass index. A very healthy subgroup (n = 270) was also defined using a written questionnaire and the Duke Health Profile. Reference intervals for the results of each test calculated from the entire group and each subgroup were compared with those recommended by the laboratory that performed the tests and with each other. Telephone calls were made to four different clinical laboratories to determine how reference intervals are set, and standard recommendations and the relevant literature were reviewed. RESULTS: The results from our study population differed significantly from laboratory recommendations on 29 of the 39 reference limits examined, at least seven of which appeared to be clinically important. In the subpopulation comparisons, "healthy" compared with everyone else, old (> or = 75 years) compared with young, high (> or = 27.1) compared with low body mass index (BMI), and white compared with nonwhite, 2, 11, 10, and 0 limits differed, respectively. None of the contacted laboratories were following published recommendations for setting reference intervals for clinical chemistries. The methods used by the laboratories included acceptance of the intervals recommended by manufacturers of test equipment, analyses of all test results from the laboratory over time, and testing of employee volunteers. CONCLUSIONS: Physicians should recognize when interpreting serum chemistry test results that the reference intervals provided may not have been determined properly. Clinical laboratories should more closely follow standard guidelines when setting reference intervals and provide more information to physicians regarding the population used to set them. Efforts should be made to provide appropriate intervals for patients of different body mass index and age.

OAFP starts practice-based resource/research network.

The Oklahoma Academy of Family Physicians, in collaboration with the University of Oklahoma Health Sciences Center, has established a primary care practice-based research network with thirteen family practice offices currently participating. The practices are connected to each other and to the Health Sciences Center campuses in Oklahoma City and Tulsa by electronic mail and have begun their first research project involving the diagnosis and treatment of brown recluse spider bites in the primary care setting.

Pharmacotherapy of urinary incontinence.

Aging is associated with many changes that may predispose an individual to urinary incontinence. An appropriate pharmacologic treatment plan depends on identification of the type of incontinence and minimization of aggravating factors. Stress incontinence is caused by incompetence of the internal urethral sphincter and is most common in postmenopausal women. This type of incontinence may respond to estrogen therapy and/or alpha-adrenergic agonists. Urge incontinence may occur in both men and women as a result of inappropriate detrusor muscle contraction. This condition may be treated with estrogens, anticholinergics or smooth muscle relaxants. Hypertonicity of the detrusor muscle, usually secondary to a neurologic problem, leads to overflow incontinence. Although overflow incontinence is difficult to control, cholinergic agonists and beta-adrenergic blockers may be helpful. Finally, any obstruction of bladder outflow may cause overflow incontinence and is best treated by amelioration of the cause. However, alpha-adrenergic blockers and 5-alpha reductase inhibitors may be useful in selected cases.