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4.
Med. intensiva (Madr., Ed. impr.) ; 40(7): 434-447, oct. 2016. tab, graf
Artigo em Inglês | IBECS | ID: ibc-156449

RESUMO

We maintain a dynamic position on extracorporeal blood purification therapies (EBPT). Continuous therapies are of choice in the hemodynamically unstable patient. We recommend their early introduction in the course of the disease, and starting with a dose of 30-35mL/kg/h. Above all, however, daily re-evaluation is required of the hemodynamic and metabolic situation and water balance of our patients in order to allow dynamic dose adjustment. Some data suggest that continuous EBPT can favorably influence the clinical course of our patients, even in the absence of acute kidney injury. The potential usefulness of hemofiltration at doses higher than the conventional doses (continuous ultrafiltration >50mL/kg/h or pulses of at least 4h a day to more than 100dosesmL/kg/h) for achieving blood purification has also been commented. We review the possible indications of this technique, together with the peculiarities of implementing these therapies in children


Creemos que las técnicas de depuración extracorpórea deben seguir un planteamiento dinámico. Las técnicas continuas son de elección en los pacientes hemodinámicamente inestables. Recomendamos un inicio precoz en el curso de la enfermedad y comenzar con una dosis de 30-35ml/kg/h. Pero, sobre todo, deberemos hacer una reevaluación diaria de la situación del paciente (hemodinámica, metabólica y del estado hidroelectrolítico) para ajustar la dosis de forma dinámica. Algunos datos evidencian que las técnicas de depuración extracorpórea continuas pueden influir favorablemente en la evolución del paciente crítico, independientemente de su función renal. Se comenta también la potencial utilidad de usar dosis de depuración superiores a las convencionales (hemofiltración superior a 50ml/kg/h o pulsos de al menos 4h diarias de más de 100ml/kg/h). Revisamos, asimismo, otras posibles indicaciones de las técnicas de depuración extracorpórea, así como las peculiaridades de su aplicación en pediatría


Assuntos
Humanos , Hemofiltração/métodos , Estado Terminal/terapia , Insuficiência Renal/terapia , Taxa de Depuração Metabólica/fisiologia
5.
Med Intensiva ; 40(7): 434-47, 2016 Oct.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-27444800

RESUMO

We maintain a dynamic position on extracorporeal blood purification therapies (EBPT). Continuous therapies are of choice in the hemodynamically unstable patient. We recommend their early introduction in the course of the disease, and starting with a dose of 30-35mL/kg/h. Above all, however, daily re-evaluation is required of the hemodynamic and metabolic situation and water balance of our patients in order to allow dynamic dose adjustment. Some data suggest that continuous EBPT can favorably influence the clinical course of our patients, even in the absence of acute kidney injury. The potential usefulness of hemofiltration at doses higher than the conventional doses (continuous ultrafiltration >50mL/kg/h or pulses of at least 4h a day to more than 100dosesmL/kg/h) for achieving blood purification has also been commented. We review the possible indications of this technique, together with the peculiarities of implementing these therapies in children.


Assuntos
Estado Terminal , Hemofiltração , Injúria Renal Aguda , Criança , Hemodinâmica , Humanos , Equilíbrio Hidroeletrolítico
13.
An Med Interna ; 24(2): 75-6, 2007 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-17590093

RESUMO

Rhodococcus equi is an unusual cause of infection in humans. Infection in immunocompetent host is extremely rare. This report describes a case of 57 years old patient Rhodococcus brain and pulmonary infection in a patient who did not have HIV or otherwise immunocompromised (either from disease, immunosuppressive medications, or both). He was admitted in the hospital due to neurological symptoms, and diagnosed after undergoing medical tests (brain CT scan and MR) with an intracranial neoplasia. No other disorders in the physical exploration or laboratory findings, included chest X ray were found. After this, he was admitted in Intensive Care Unit due to a respiratory failure, performing CT lung that showed pulmonary nodules. An stereoataxic brain biopsy was performed due to patient worsening. Pulmonary and brain cultures isolated Rhodococcus equi both. He was treated with intravenous vancomycin, cotrimoxazole and rifampicin. Despite the mortality rate among immunocompetent patients is really uncommon, the patient died.


Assuntos
Infecções por Actinomycetales/diagnóstico , Abscesso Encefálico/diagnóstico , Rhodococcus equi , Soronegatividade para HIV , Humanos , Masculino , Pessoa de Meia-Idade
14.
An. med. interna (Madr., 1983) ; 24(2): 75-76, feb. 2007. ilus
Artigo em Es | IBECS | ID: ibc-053947

RESUMO

El Rhodococcus equi es una causa inusual de infección en los humanos. La infección en los pacientes inmunocompetentes es extremadamente rara. A continuación exponemos el caso de un paciente de 57 años con infección cerebral y pulmonar secundaria a Rhodococcus equi en ausencia de compromiso inmunitario. Inicialmente ingresado en el hospital debido a síntomas neurológicos y diagnosticado de un proceso cerebral neoplásico tras la realización de TAC y RNM. El resto de la exploración física y exploraciones complementarias fueron normales, incluyendo la Rx de tórax. Posteriormente es ingresado en la UCI debido a una insuficiencia respiratoria, por lo que se realizó TAC torácica mostrando nódulos pulmonares. Debido al empeoramiento del paciente se practicó una biopsia esteroatáxica. En los diferentes cultivos extraídos (lavado broncoalveolar, y cerebral) se aislo Rhodococcus equi. Fue tratado con vancomicina, sulfametoxazol y rifampicina intravenosas. A pesar de que la tasa de mortalidad entre los pacientes inmunocompetentes es muy infrecuente el paciente falleció


Rhodococcus equi is an unusual cause of infection in humans. Infection in immunocompetent host is extremely rare. This report describes a case of 57 years old patient Rhodococcus brain and pulmonary infection in a patient who did not have HIV or otherwise immunocompromised (either from disease, immunosuppressive medications, or both). He was admitted in the hospital due to neurological symptoms, and diagnosed after undergoing medical tests (brain CT scan and MR) with an intracranial neoplasia. No other disorders in the physical exploration or laboratory findings, included chest X ray were found. After this, he was admitted in Intensive Care Unit due to a respiratory failure, performing CT lung that showed pulmonary nodules. An stereoataxic brain biopsy was performed due to patient worsening. Pulmonary and brain cultures isolated Rhodococcus equi both. He was treated with intravenous vancomycin, cotrimoxazole and rifampicin. Despite the mortality rate among immunocompetent patients is really uncommon, the patient died


Assuntos
Masculino , Pessoa de Meia-Idade , Humanos , Rhodococcus equi/patogenicidade , Infecções por Actinomycetales/complicações , Abscesso Encefálico/microbiologia , Pneumonia Bacteriana/complicações
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