Bacteremia during COVID-19 pandemic in a tertiary hospital in Spain.

INTRODUCTION: The reasons for the decrease in blood cultures were investigated and the rate and aetiology of bacteremia and contaminated blood cultures collected from COVID and non-COVID patients were assessed. METHODS: We performed a retrospective analysis in a tertiary hospital in Spain during the COVID period from 4th March 2020 to 21st June 2020. RESULTS: The number of blood cultures processed was 5313, representing 22.7% and 18.8% of decrease compared to the same months of 2019 and 2018, respectively (p=0.173). The rate of bacteremia was 1.2% higher among COVID-patients than among non-COVID patients (p<0.001). COVID patients had a higher proportion of nosocomial bacteremia (95.5%) than non-COVID patients (30.5%) (p<0.001). In COVID-positive patients, the contamination rate was 12.3% vs 5.7% in non-COVID patients (p<0.001). CONCLUSION: There was a decrease in the number of blood cultures collected during the COVID period compared to previous years. Bacteremia in COVID patients was mainly nosocomial and catheter-related.

Bacteremia during COVID-19 pandemic in a tertiary hospital in Spain / Bacteriemia durante la pandemia de COVID-19 en un hospital terciario de España

IntroductionThe reasons for the decrease in blood cultures were investigated and the rate and aetiology of bacteremia and contaminated blood cultures collected from COVID and non-COVID patients were assessed.MethodsWe performed a retrospective analysis in a tertiary hospital in Spain during the COVID period from 4th March 2020 to 21st June 2020.ResultsThe number of blood cultures processed was 5313, representing 22.7% and 18.8% of decrease compared to the same months of 2019 and 2018, respectively (p=0.173). The rate of bacteremia was 1.2% higher among COVID-patients than among non-COVID patients (p<0.001). COVID patients had a higher proportion of nosocomial bacteremia (95.5%) than non-COVID patients (30.5%) (p<0.001). In COVID-positive patients, the contamination rate was 12.3% vs 5.7% in non-COVID patients (p<0.001).ConclusionThere was a decrease in the number of blood cultures collected during the COVID period compared to previous years. Bacteremia in COVID patients was mainly nosocomial and catheter-related.

IntroducciónInvestigar la causa de la disminución de los hemocultivos recibidos y evaluar la tasa y la etiología de la bacteriemia y la contaminación de los hemocultivos extraídos en pacientes con COVID-19 y sin COVID-19.MétodosEstudio retrospectivo en un hospital de tercer nivel en España durante el periodo de COVID-19 del 4 de marzo al 21 de junio de 2020.ResultadosSe procesaron 5.313 hemocultivos, representando una disminución del 22,7 y 18,8% respecto de los mismos meses de 2019 y 2018 (p = 0,173). La tasa de bacteriemia fue 1,2% superior en pacientes con COVID-19 (p < 0,001). Los pacientes positivos en COVID-19 tenían una mayor proporción de bacteriemia nosocomial (95,5%) que los pacientes sin COVID-19 (30,5%) (p < 0,001). En pacientes positivos en COVID-19, la tasa de contaminación fue del 12,3 vs. 5,7% en pacientes sin COVID-19 (p < 0,001).ConclusiónDurante el periodo de COVID-19 disminuyó el número de hemocultivos recibidos, en comparación con años anteriores. La bacteriemia en pacientes con COVID-19 fue principalmente nosocomial y se asoció con el catéter.

Impacto del SARS-CoV-2 en el diagnóstico de bacteriemia comunitaria en un hospital terciario / Impact of SARS-COV-2 on the diagnosis of community bacteremia in a tertiary hospital

Objetivo. Realizar un análisis de las bacteriemias diagnosticadas en urgencias durante el año 2020, coincidiendo con el periodo de la pandemia Métodos. Estudio retrospectivo en un hospital de tercer nivel en España durante el período COVID del 4 de marzo al 31 de diciembre de 2020. Resultados. El número de pacientes atendidos en urgencias durante el periodo de estudio y el número de hemocultivos extraídos sufrieron un descenso del 46,79% y del 35.7% respecto al mismo periodo de 2019 (p<0.05). Se produjeron 320 bacteriemias mientas que en 2019 se produjeron 507, suponiendo un descenso del 36,8% (p<0,05). La tasa de positividad de los hemocultivos fue del 7,09 % en 2020 y del 7,23 % en 2019 y la tasa de contaminación del 7,07 % en 2020 y 5,67 % en 2019. El microorganismo más frecuente aislado fue Escherichia coli, seguido de Staphylococcus aureus y de Klebsiella pneumoniae. El 6,62% de los E. coli aislados fueron portadores de beta-lactamasas de espectro extendido (BLEE). El porcentaje de S. aureus resistente a meticilina fue de 12,9 % y el de K. pneumoniae BLEE fue del 11,54 %. Conclusión. Durante la pandemia por SARS-CoV-2 se ha producido una disminución en el número de diagnósticos de bacteriemia, es posible que la atención estuviera centrada especialmente en la COVID descuidando otras enfermedades, como es el caso de la bacteriemia. (AU)

Objective. We carry out an analysis of the bacteremia diagnosed in the Emergency Department during 2020, coinciding with the period of the pandemic. Method. We performed a retrospective analysis from March 4, 2020 to December 31, 2020. Results. The number of patients who went to the Emergency Department during the study period and the number of extracted blood cultures decreased by 46.79% and 35.7% compared to the same period in 2019 (p <0.05). 320 bacteremia occurred while 507 occurred in 2019, assuming a decrease of 36.8% (p <0.05). The positivity rate of blood cultures was 7.09% in 2020 and 7.23% in 2019 and the contamination rate was 7.07 % in 2020 and 5.67% in 2019. The most frequently isolated microorganism was Escherichia coli, followed by Staphylococcus aureus and Klebsiella pneumoniae. A 6.62% of the isolated E. coli were carriers of extended-spectrum beta-lactamases (ESBL). The percentage of methicillin-resistant S. aureus was 12.9 % and that of K. pneumoniae ESBL was 11.54%. Conclusion. During the SARS-CoV-2 pandemic there has been a decrease in the number of bacteremia diagnoses, it is possible that attention was focused especially on COVID, forgetting other diseases, such as bacteremia. (AU)

Bacteremia during COVID-19 pandemic in a tertiary hospital in Spain.

INTRODUCTION: The reasons for the decrease in blood cultures were investigated and the rate and aetiology of bacteremia and contaminated blood cultures collected from COVID and non-COVID patients were assessed. METHODS: We performed a retrospective analysis in a tertiary hospital in Spain during the COVID period from 4th March 2020 to 21st June 2020. RESULTS: The number of blood cultures processed was 5313, representing 22.7% and 18.8% of decrease compared to the same months of 2019 and 2018, respectively (p=0.173). The rate of bacteremia was 1.2% higher among COVID-patients than among non-COVID patients (p<0.001). COVID patients had a higher proportion of nosocomial bacteremia (95.5%) than non-COVID patients (30.5%) (p<0.001). In COVID-positive patients, the contamination rate was 12.3% vs 5.7% in non-COVID patients (p<0.001). CONCLUSION: There was a decrease in the number of blood cultures collected during the COVID period compared to previous years. Bacteremia in COVID patients was mainly nosocomial and catheter-related.