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Tumori ; 77(6): 460-4, 1991 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-1803709

RESUMO

We have examined the possibility of obtaining primary cultures from breast tissue utilizing a method especially developed for breast epithelium. The number of specimens able to grow in culture was very high: 82.8%, 64.3%, 75.0% and 77.8%, respectively, for primary breast cancer, skin recurrences, inflammatory breast cancer and normal breast tissue. In our experience, growth was not related to menopausal status or histopathologic type, whereas for skin recurrences, a prior pharmacologic treatment (chemotherapy) of the patient enhanced the growth capacity of the tissue. This culture method could help to study the basic biology of breast epithelia and to improve the chemotherapy approach of breast cancer patients.


Assuntos
Neoplasias da Mama/patologia , Técnicas de Cultura/métodos , Epitélio/patologia , Feminino , Humanos , Recidiva Local de Neoplasia/patologia
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