RESUMO
An overall median survival time (MST) and prognostic factors in rabbits with thymomas treated with megavoltage radiation therapy (RT) were determined in this multi-institutional retrospective case analysis. Medical records for 19 rabbits with suspected or confirmed thymomas treated with RT were evaluated for data including signalment, haematological and serum biochemistry abnormalities, presence of pleural effusion, radiation plan, body weight, total radiation dose and institution administering RT. Statistical significance of these factors related to overall survival was assessed. An overall MST for all 19 rabbits was 313 days; exclusion of 3 rabbits that died acutely during the first 14 days of RT yielded a MST of 727 days. The only factor associated with a significantly decreased survival time was having a body weight lower than mean body weight of 1.57 kg. Radiation treatment-associated complications were infrequent and included radiation-induced myocardial failure, radiation pneumonitis and alopecia.
Assuntos
Coelhos , Radioterapia de Alta Energia/veterinária , Timoma/veterinária , Neoplasias do Timo/veterinária , Animais , Cálcio/sangue , Feminino , Masculino , Prognóstico , Radioterapia de Alta Energia/efeitos adversos , Estudos Retrospectivos , Taxa de Sobrevida , Timoma/mortalidade , Timoma/radioterapia , Neoplasias do Timo/mortalidade , Neoplasias do Timo/radioterapia , Resultado do TratamentoRESUMO
A variety of pharmacologic agents are currently available to treat house rabbits. In many cases, dosages are based on extrapolation from other species or empirical data. Dosing in rabbits is further complicated by individual variation. An understanding of rabbit physiology and the pharmacology of prescribed medications helps ensure that the agents are used as effectively and safely as possible. In this article, basic rabbit pharmacobiology is reviewed and techniques for drug administration are described. A formulary for house rabbits is provided.
Assuntos
Doenças dos Animais/tratamento farmacológico , Coelhos , Animais , Formulários Farmacêuticos como Assunto , Drogas VeterináriasRESUMO
Diagnostic sampling and interpretation in the ferret are similar to other small mammals in many ways. There are several aspects of clinical pathology and diagnostic procedures, however, that are unique to the ferret. This article is designed to assist the clinician in obtaining and interpreting diagnostic samples for the ferret. Methods for blood and urine collection, bone marrow and organ aspirations, and organ biopsy techniques are discussed.
