Effectiveness of Psychobiotics in the Treatment of Psychiatric and Cognitive Disorders: A Systematic Review of Randomized Clinical Trials.

In this study, a systematic review of randomized clinical trials conducted from January 2000 to December 2023 was performed to examine the efficacy of psychobiotics-probiotics beneficial to mental health via the gut-brain axis-in adults with psychiatric and cognitive disorders. Out of the 51 studies involving 3353 patients where half received psychobiotics, there was a notably high measurement of effectiveness specifically in the treatment of depression symptoms. Most participants were older and female, with treatments commonly utilizing strains of Lactobacillus and Bifidobacteria over periods ranging from 4 to 24 weeks. Although there was a general agreement on the effectiveness of psychobiotics, the variability in treatment approaches and clinical presentations limits the comparability and generalization of the findings. This underscores the need for more personalized treatment optimization and a deeper investigation into the mechanisms through which psychobiotics act. The research corroborates the therapeutic potential of psychobiotics and represents progress in the management of psychiatric and cognitive disorders.

Neuroinflammation and Schizophrenia: New Therapeutic Strategies through Psychobiotics, Nanotechnology, and Artificial Intelligence (AI).

The prevalence of schizophrenia, affecting approximately 1% of the global population, underscores the urgency for innovative therapeutic strategies. Recent insights into the role of neuroinflammation, the gut-brain axis, and the microbiota in schizophrenia pathogenesis have paved the way for the exploration of psychobiotics as a novel treatment avenue. These interventions, targeting the gut microbiome, offer a promising approach to ameliorating psychiatric symptoms. Furthermore, advancements in artificial intelligence and nanotechnology are set to revolutionize psychobiotic development and application, promising to enhance their production, precision, and effectiveness. This interdisciplinary approach heralds a new era in schizophrenia management, potentially transforming patient outcomes and offering a beacon of hope for those afflicted by this complex disorder.

Factors of abandonment of tuberculosis treatment in the public health network.

This study determines the factors of abandonment of tuberculosis treatment in the public health network of Cali, Colombia, during years 2016 to 2018. We conducted an operational case-control investigation including 224 patients with tuberculosis (112 abandoned treatment and 112 completed it). We found that treatment abandonment for tuberculosis is driven by factors related to the individuals and health services that facilitate non-adherence and drive them away from the care provided in medical institutions.

Factors of abandonment of tuberculosis treatment in the public health network / Factores de abandono al tratamiento de la tuberculosis en la red pública de salud

ABSTRACT This study determines the factors of abandonment of tuberculosis treatment in the public health network of Cali, Colombia, during years 2016 to 2018. We conducted an operational case-control investigation including 224 patients with tuberculosis (112 abandoned treatment and 112 completed it). We found that treatment abandonment for tuberculosis is driven by factors related to the individuals and health services that facilitate non-adherence and drive them away from the care provided in medical institutions.

RESUMEN Este estudio determina los factores de abandono al tratamiento de la tuberculosis en la red pública de salud de Cali, Colombia, durante los años 2016 a 2018. Se realizó una investigación operativa de casos y controles en la que se incluyeron 224 pacientes con tuberculosis (112 abandonaron el tratamiento y 112 lograron completarlo). Se encuentra que el abandono del tratamiento para la tuberculosis está impulsado por factores relacionados con el individuo y los servicios de salud que facilitan la no adherencia y los alejan de la atención brindada en las instituciones médicas.

Universidad saludable: una estrategia interdisciplinaria para la construcción de un entorno saludable / Healthy university: an interdisciplinary strategy for the construction of a healthy environment

Los entornos o escenarios universitarios son definidos como aquellos luga- res y contextos sociales donde las personas desarrollan actividades diarias y en los cuales interactúan factores ambientales, organizativos y personales que afectan la salud y el bienestar de los que trabajan, y aprenden en ellos. Las Instituciones de Educación Superior no son ajenas al concepto salud y de hecho han venido formando profesionales relacionados con la salud en un entorno de transmisión y producción del conocimiento, pero también de interacción y comunicación, abierto y accesible, que favorece la vida salu- dable, la cultura y el disfrute de sus espacios; sin embargo poco sabemos cómo hacer buen uso de tantos recursos para llegar a ser una universidad promotora de la salud. En particular, la Universidad Santiago de Cali, reúne varias de las carac- terísticas de estos entornos; por un lado, es un centro de trabajo, un centro educativo y además es una institución de especial relevancia en tanto que en ella confluye un gran número de estudiantes, profesores, empleados y directivos que se ven expuestos a los factores determinantes de la salud que este entorno propicia. Muchos de los hábitos de vida que influyen en la salud se inician y se con- solidan en la etapa universitaria, sin embargo los espacios de atención en este entorno se orientan a atender problemas relacionados con la enferme- dad sin lograr estilos de vida saludable ni conductas de autocuidado. Este libro es el resultado de un sinnúmero de discusiones académicas en- tre los grupos de investigación de la Facultad de Salud de la Universidad Santiago de Cali, durante los años 2012-2013, en torno a cómo mejorar la salud de las personas pertenecientes a la comunidad universitaria.