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Am J Surg ; 219(5): 790-794, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-32145921

RESUMO

INTRODUCTION: Wide excision margins are traditionally recommended for phyllodes tumours of the breast to reduce recurrence. Recent studies suggest margin status and histopathological features, excluding margin width, influence recurrence. This study evaluated treatment outcomes for phyllodes tumours and examined predictors of recurrence. METHODS: Clinical and follow-up information for phyllodes tumours patients treated between 2008 and 2017 were obtained from chart review. Tumour subtype and histopathological features were determined from pathology reports. Primary endpoints were recurrence rate and time to recurrence or mortality. RESULTS: Among 96 patients, there were 6 local and 1 distant recurrences. Overall recurrence rate was 7.3% and average time-to-recurrence was 13.7 months. Tumour size, margin status, necrosis, and mitoses were associated with recurrence; margin width was not. Two deaths (2.1%) from malignant phyllodes occurred. CONCLUSIONS: Multiple histopathological features influence phyllodes recurrence. Wide excision and re-excising positive margins for benign tumours was not beneficial.


Assuntos
Neoplasias da Mama/cirurgia , Recidiva Local de Neoplasia/patologia , Tumor Filoide/cirurgia , Adulto , Neoplasias da Mama/patologia , Feminino , Humanos , Margens de Excisão , Pessoa de Meia-Idade , Tumor Filoide/patologia , Fatores de Risco , Fatores de Tempo
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