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1.
Am J Case Rep ; 23: e935544, 2022 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-35989479

RESUMO

BACKGROUND Lamellar ichthyosis is a rare type of hereditary ichthyosis disease that is responsible for generalized dry skin and severe scaling. Congenital ectropion and eclabium are often associated with this condition. The ectropion can cause many ophthalmologic complications, mostly due to corneal exposure caused by the lack of eyelid cleft closure. The corneal exposure can cause ulceration and even corneal perforation leading to phthisis bulbi. CASE REPORT We report the case of a North African newborn baby diagnosed with congenital lamellar ichthyosis responsible for severe skin scaling, eclabium, and bilateral ectropion of both the upper and lower eyelids. The therapeutic care of the baby was ensured by a collaboration between ophthalmologist and dermatologist. The newborn was treated by oral acitretin and skin emollients for his dermatological conditions and on the ophthalmological level he was put on lubricating and moisturizing eye drops and gel, associated with daily repeated eyelid massage. The evolution after 6 months of treatment showed excellent results on both the dermatological and the ophthalmological level. CONCLUSIONS At the stage of cicatricial ectropion in lamellar ichthyosis, the management is mainly based on a chirurgical approach. However, if the ectropion is managed early enough, the treatment could be medical, which is much easier, produces very good results, and prevents the progression toward eyelid fibrosis and its associated complications that can make the management of the ectropion much harder.


Assuntos
Ectrópio , Ictiose Lamelar , Ectrópio/complicações , Ectrópio/diagnóstico , Pálpebras/cirurgia , Humanos , Ictiose Lamelar/complicações , Ictiose Lamelar/diagnóstico , Lactente , Recém-Nascido , Masculino , Pele
2.
Pan Afr Med J ; 32: 177, 2019.
Artigo em Francês | MEDLINE | ID: mdl-31312291

RESUMO

Molluscums contagiosum (MC) are benign skin lesions caused by Molluscipoxvirus, primarily affecting children and young adults. They manly involve the skin and rarely the mucous membranes. Clinical diagnosis is easy, confirmed by histological examination of the lesion. However there is no consensus regarding therapy. Eyelid molluscum contagiosum is rare, posing a problem of differential diagnosis especially when it is isolated as well as a therapeutic problem given the proximity of the eyeball. We report the case of a 7-year old girl with isolated eyelid lesion. The patient underwent lesion excision. Anatomopathological examination showed molluscum contagiosum. This study aims to describe the clinical, therapeutic and evolutionary features of this rare localization of molluscum contagiosum.


Assuntos
Doenças Palpebrais/diagnóstico , Molusco Contagioso/diagnóstico , Criança , Diagnóstico Diferencial , Doenças Palpebrais/cirurgia , Doenças Palpebrais/virologia , Feminino , Humanos , Molusco Contagioso/cirurgia
3.
Pan Afr Med J ; 26: 98, 2017.
Artigo em Francês | MEDLINE | ID: mdl-28491229

RESUMO

Choroidal neovessels are a threatening complication of high myopia, accounting for 5 to 10% of cases. They require immediate treatment because of their poor prognosis. Anti-VEGF intravitreal injections are currently a new therapeutic alternative far exceeding photodynamic therapy (PDT). Nevertheless, anti-VEGF treatment algorithm for this type of neovessels remains a matter of discussion among the authors. The purpose of this study was to highlight the difficulties in managing these neovessels and to discuss the Anti-VEGF therapeutic regimen to follow.


Assuntos
Inibidores da Angiogênese/uso terapêutico , Neovascularização de Coroide/tratamento farmacológico , Miopia Degenerativa/tratamento farmacológico , Fator A de Crescimento do Endotélio Vascular/antagonistas & inibidores , Idoso , Algoritmos , Inibidores da Angiogênese/administração & dosagem , Inibidores da Angiogênese/farmacologia , Neovascularização de Coroide/etiologia , Humanos , Injeções Intravítreas , Masculino , Miopia Degenerativa/complicações , Prognóstico
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