RESUMO
Nodular fasciitis is a relatively rare benign lesion of the soft tissue, which often presents in the fascia or deep subcutaneous tissues. It most commonly presents in the upper extremities and trunk and the head and neck region, particularly in younger patients. Its pathogenesis is poorly understood and it is predominantly thought to be a reactive lesion, although some have suggested that it may be a benign neoplasm. Advances in molecular testing and imaging have greatly assisted diagnosis. We discuss the benefits of ubiquitin-specific protease 6 (USP6) gene rearrangement testing and magnetic resonance imaging (MRI) to aid this uncommon diagnosis.
Assuntos
Fáscia/diagnóstico por imagem , Fáscia/patologia , Fasciite/diagnóstico por imagem , Fasciite/patologia , Articulação Temporomandibular/diagnóstico por imagem , Articulação Temporomandibular/patologia , Diagnóstico Diferencial , Diagnóstico por Imagem , Fasciite/genética , Fasciite/cirurgia , Rearranjo Gênico , Humanos , Hibridização in Situ Fluorescente , Imageamento por Ressonância Magnética/métodos , Mutação , Proteínas Proto-Oncogênicas/genética , Articulação Temporomandibular/cirurgia , Ubiquitina Tiolesterase/genéticaRESUMO
Sarcoidosis is a multi-system disease of unknown aetiology characterised by the presence of non-caseating granulomas, the lungs and lymph nodes being the most affected sites. Orofacial manifestations of the condition are increasingly recognised, with several recent case reports where the initial presentation of the disease is in the region. Here, we report six cases of orofacial sarcoidosis which help to illustrate the wide spectrum of the condition.
