Enfermedad tromboembólica venosa: análisis de 239 casos / Thromboembolic diseases: analysis of 239 cases

Objetivo: Conocer el número de pacientes que ingresan o que desarrollan durante su ingreso en un hospital ETEV, analizar el manejo de esta enfermedad y sentar las bases para un estudio prospectivo de dicha enfermedad. Métodos: Se trata de un estudio descriptivo retrospectivo de pacientes diagnosticados de ETEV durante su ingreso en el Hospital Clínico San Carlos de Madrid en un período de 6 meses. Se recogen los datos relacionados con antecedentes epidemiológicos, diagnóstico, tratamiento y complicaciones de los pacientes con trombosis venosa profunda (TVP), tromboembolismo pulmonar (TEP) o ambas (TVP + TEP). Resultados: Del 1 de octubre de 2003 al 31 de marzo de 2004, 239 pacientes fueron diagnosticados de ETEV (64 TVP, 125 TEP y 51 TVP + TEP) al alta en nuestro hospital con una edad media de 73,2 años (desviación estándar 13,64). Como factores de riesgo con diferencias estadísticamente significativas detectamos la quimioterapia, el infarto agudo de miocardio y la obesidad. No se ha observado relación entre el tipo de tratamiento utilizado y la aparición de hemorragia. Los pacientes con episodios previos de ETEV presentaron hemorragias más frecuentemente que aquellos sin dichos antecedentes. La hipocinesia de ventrículo derecho en el ecocardiograma fue un factor de mal pronóstico para la muerte por ETEV así como la aparición de TVP + TEP. Conclusión: En más del 50% de los pacientes la ETEV era TEP y más del 60% eran mujeres. Es importante disponer de información sobre estos pacientes, ya que 2/3 ingresan en medicina interna. La quimioterapia, el IAM y la obesidad fueron factores que se asociaron a TVP, TEP y TVP + TEP de forma significativa, respectivamente. La hipocinesia de ventrículo derecho en el ecocardiograma fue un factor de mal pronóstico para la muerte por ETEV así como la coincidencia de TVP + TEP

Aim: To know the number of patients that are admitted in the hospital with TED or those who have developed it during their stay, analyzing how to manage this disease and make a basis for a prospective study of this disease. Methods: It is a descriptive and retrospective study of TED diagnosed patients during their stay at the Hospital Clínico San Carlos of Madrid for a 6 month period. Data related with epidemiologic records, diagnosis, treatment and complications of patients with Deep-Vein Thrombosis (DVT), Pulmonary Thromboembolism (PTE) or both (DVT+PTE) are collected. Results: From October 1st of 2003 to March 31st of 2004, 239 patients were diagnosed with TED (64 DVT, 125 PTE y 51 DVT + PTE) when they were discharged from our hospital, with an average age of 73.2 years (standar desviation 13.64). We classify as risky factors with significative statistical diferences chemotherapy, acute myocardium infarction and obesity. It has not been found any relation between the treatment used and the development of hemorrage. Patients with previous episodies of TED had more frequent hemorragies than those without such records. Hypokinesia in the right ventricle shown on the echocardiogram supposed a gloomy prognosis of the death for TED as well as the development of DVT + PTE. Conlusion: In more than a 50% of patients, TED was PTE and more than a 60% were women. It is important to obtain information about these patients because 2/3 of them are admitted to internal medicine. Chemotherapy, AIM and obesity were factors significatively associated to DVT, PTE and DVT + PTE. Hypokinesia in the right ventricle shown on the echocardiogram supposed a gloomy prognosis for TED as well as the development of DVT + PTE

[Thromboembolic disease: analysis of 239 cases]. / Enfermedad tromboembólica venosa: análisis de 239 casos.

AIM: To know the number of patients that are admitted in the hospital with TED or those who have developed it during their stay, analyzing how to manage this disease and make a basis for a prospective study of this disease. METHODS: It is a descriptive and retrospective study of TED diagnosed patients during their stay at the Hospital Clínico San Carlos of Madrid for a 6 month period. Data related with epidemiologic records, diagnosis, treatment and complications of patients with Deep-Vein Thrombosis (DVT), Pulmonary Thromboembolism (PTE) or both (DVT+PTE) are collected. RESULTS: From October 1st of 2003 to March 31st of 2004, 239 patients were diagnosed with TED (64 DVT, 125 PTE y 51 DVT + PTE) when they were discharged from our hospital, with an average age of 73.2 years (standard desviation 13.64). We classify as risky factors with significative statistical differences chemotherapy, acute myocardium infarction and obesity. It has not been found any relation between the treatment used and the development of hemorrhage. Patients with previous episodes of TED had more frequent hemorrhagies than those without such records. Hypokinesia in the right ventricle shown on the echocardiogram supposed a gloomy prognosis of the death for TED as well as the development of DVT + PTE. CONCLUSION: In more than a 50% of patients, TED was PTE and more than a 60% were women. It is important to obtain information about these patients because 2/3 of them are admitted to internal medicine. Chemotherapy, AIM and obesity were factors significatively associated to DVT, PTE and DVT + PTE. Hypokinesia in the right ventricle shown on the echocardiogram supposed a gloomy prognosis for TED as well as the development of DVT + PTE.