[Experience with the use of IRS-19 for the rehabilitation of children after acute respiratory infections].

The purpose of this work was to evaluate the efficacy of the prevention of recurrent respiratory infections with the use of the immunomodulatory respiratory spray (IRS-19). The study involved 60 children at the age from 4 to 7 years allocated to three groups. Group 1 was comprised of 20 children treated by two daily irrigation of nasal sinuses with a seawater solution. Group 2 included 20 children treated by irrigation of nasal sinuses with IRS-19 twice daily during 2 weeks.. Group 3 consisted of 20 children treated by irrigation of nasal sinuses with a saline solution and topical immunostimulator IRS-19 twice daily. It was shown that therapy with IRS-19 resulted in a more than two-fold reduction in the frequency of relapses of the acute respiratory infections as compared with control.

[Dynamics of immunological characteristics and investigation of apoptosis of palatal tonsillar lymphocytes in patients presenting with chronic tonsillitis and treated by conservative therapy].

The enhanced amount of viable lymphocytes and the decreased number of apoptotic cells as well as the reduced levels of IgA and IgM and the elevated concentration of sIgA in lacunar secretion are considered to be the reliable criteria for the efficacy of the conservative treatment of chronic tonsillitis. Combined therapy of this condition including irrigation of the palatal tonsillar lacunae with a miramistin solution, their contact ultrasonic treatment, and application of imudon makes it possible to maintain the optimal ratio of viable to apoptotic lymphocytes during a period of up to 6-7 months.