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Sci Rep ; 11(1): 24511, 2021 12 31.
Artigo em Inglês | MEDLINE | ID: mdl-34972829

RESUMO

Latex, a milky substance found in a variety of plants which is a natural source of biologically active compounds. In this study, Latex was collected from raw Carica papaya and was characterized using UV-Vis, FTIR and GC-MS analyses. Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) were synthesized, coated with C. papaya latex (PL-Sp) and characterized using UV-Vis, FT-IR, SEM-EDX, XRD, VSM and Zeta potential analyses. SPIONs and latex coated SPIONs (PL-Sp) were used in batch adsorption study for effective removal of Methylene blue (MB) dye, where (PL-Sp) removed MB dye effectively. Further the PL-Sp was used to produce a nanoconjugate loaded with curcumin and it was characterized using UV-Vis spectrophotometer, FT-IR, SEM-EDX, XRD, VSM and Zeta potential. It showed a sustained drug release pattern and also found to have good antibacterial and anticancer activity.


Assuntos
Carica/química , Materiais Revestidos Biocompatíveis/química , Corantes/química , Portadores de Fármacos , Látex/química , Nanopartículas de Magnetita/química , Compostos Fitoquímicos/química , Fenômenos Químicos , Corantes/análise , Composição de Medicamentos , Sistemas de Liberação de Medicamentos , Nanopartículas de Magnetita/ultraestrutura , Nanotecnologia , Análise Espectral
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