IndicDialogue: A dataset of subtitles in 10 Indic languages for Indic language modeling.

The Languages of the Indian subcontinent are less represented in current NLP literature. To mitigate this gap, we present the IndicDialogue dataset, which contains subtitles and dialogues in 10 major Indic languages: Hindi, Bengali, Marathi, Telugu, Tamil, Urdu, Odia, Sindhi, Nepali, and Assamese. This dataset is sourced from OpenSubtitles.org, with subtitles pre-processed to remove irrelevant tags, timestamps, square brackets, and links, ensuring the retention of relevant dialogues in JSONL files. The IndicDialogue dataset comprises 7750 raw subtitle files (SRT), 11 JSONL files, 6,853,518 dialogues, and 42,188,569 words. It is designed to serve as a foundation for language model pre-training for low-resource languages, enabling a wide range of downstream tasks including word embeddings, topic modeling, conversation synthesis, neural machine translation, and text summarization.

Effect of Alvimopan on Postoperative Ileus and Length of Hospital Stay in Patients Undergoing Bowel Resection: A Systematic Review and Meta-Analysis.

AIMS: The aim is to investigate the effect of alvimopan on postoperative ileus and length of hospital stay in patients undergoing bowel resection. METHODS: The PRISMA statement standards were followed to conduct a systematic review and meta-analysis. The available literature was searched to identify all studies comparing alvimopan with no alvimopan in patients undergoing bowel resection. Postoperative ileus and length of hospital stay were the primary outcomes, and time to first bowel motion was the secondary outcome. Random-effects modeling was applied for analyses. RESULTS: Analysis of 94 833 patients from 26 studies showed that alvimopan was associated with lower risk of postoperative ileus (OR: .57, 95% CI .48 to .67, P <.00001; high GRADE certainty), shorter length of hospital stay (MD: -1.08 day, 95% CI -1.36 to -.81, P < .00001; moderate GRADE certainty), and shorter time to first bowel motion (MD: -.43 day, 95% CI -.58 to -.28, P < .00001; moderate GRADE certainty). Separate analyses of randomized controlled trials and observational studies showed similar findings. Subgroup analyses suggested consistent findings in patients undergoing elective bowel resection, emergency bowel resection, and open surgery; however, alvimopan did not improve the outcomes in patients undergoing minimally invasive surgery. CONCLUSION: Robust evidence supports the routine use of alvimopan in patients undergoing open bowel resection as indicated by lower risk of postoperative ileus and shorter length of hospital stay. We support incorporation of alvimopan into enhanced recovery after surgery programs for the procedures involving open bowel resection. The role of alvimopan in minimally invasive bowel resection needs more research.

Prognostic value of hematological parameters in older adult patients with acute coronary syndrome undergoing coronary intervention: a single centre prospective study.

BACKGROUND: Cardiovascular disease is a significant contributor to the disease burden in geriatric patients. Underlying systemic inflammation is thought to be the cause of age-related changes in the bone marrow and a major risk factor for atherosclerosis. The purpose of the study was to assess the accuracy of these hematological biomarkers in predicting 30-day mortality in older patients with acute coronary syndrome (ACS). METHODS: This was a prospective observational study of 601 older adult patients (age > 60 years) with ACS who underwent percutaneous coronary intervention over two years (2017-2019). The relationship between baseline hematological parameters and mortality was assessed during the 30-day follow-up. Logistic regression analysis and receiver operating characteristic curve analysis were done to evaluate for diagnostic accuracy of various hematological parameters. RESULTS: The mean age of presentation was 77 ± 17 years. The mean neutrophil-lymphocyte ratio (NLR) value was 5.07 ± 4.90 and the mean platelet-lymphocyte ratio (PLR) value was 108.65 ± 85.82. On univariate analysis, total leucocyte count [odds ratio (OR) = 0.85, P = 0.021], hematocrit (OR = 0.91, P = 0.018), NLR (OR = 1.10, P = 0.001) and PLR (OR = 1.05, P = 0.001) were associated with mortality. On receiver operating characteristic curve analysis, NLR predicted mortality with 68.1% and PLR with 65.7% accuracy. On multivariate analysis, NLR (OR = 1.096, 95% CI: 1.006-1.15, P = 0.035) was an independent predictor of 30-day mortality. CONCLUSIONS: For the risk classification of all elderly ACS patients, we highly advise using NLR rather than the total white blood cell count.

Prognostic value of hematological parameters in older adult patients with acute coronary syndrome undergoing coronary intervention: a single centre prospective study / 老年心脏病学杂志（英文版）

BACKGROUND@#Cardiovascular disease is a significant contributor to the disease burden in geriatric patients. Underlying systemic inflammation is thought to be the cause of age-related changes in the bone marrow and a major risk factor for atherosclerosis. The purpose of the study was to assess the accuracy of these hematological biomarkers in predicting 30-day mortality in older patients with acute coronary syndrome (ACS).@*METHODS@#This was a prospective observational study of 601 older adult patients (age > 60 years) with ACS who underwent percutaneous coronary intervention over two years (2017-2019). The relationship between baseline hematological parameters and mortality was assessed during the 30-day follow-up. Logistic regression analysis and receiver operating characteristic curve analysis were done to evaluate for diagnostic accuracy of various hematological parameters.@*RESULTS@#The mean age of presentation was 77 ± 17 years. The mean neutrophil-lymphocyte ratio (NLR) value was 5.07 ± 4.90 and the mean platelet-lymphocyte ratio (PLR) value was 108.65 ± 85.82. On univariate analysis, total leucocyte count [odds ratio (OR) = 0.85, P = 0.021], hematocrit (OR = 0.91, P = 0.018), NLR (OR = 1.10, P = 0.001) and PLR (OR = 1.05, P = 0.001) were associated with mortality. On receiver operating characteristic curve analysis, NLR predicted mortality with 68.1% and PLR with 65.7% accuracy. On multivariate analysis, NLR (OR = 1.096, 95% CI: 1.006-1.15, P = 0.035) was an independent predictor of 30-day mortality.@*CONCLUSIONS@#For the risk classification of all elderly ACS patients, we highly advise using NLR rather than the total white blood cell count.

Thermal enhancement in Falkner-Skan flow of the nanofluid by considering molecular diameter and freezing temperature.

The analysis of nanofluids heat transfer over a wedge is very important due to their wider applications in applied thermal engineering, chemical engineering and biomedical engineering etc. Therefore, aim of the study is to explore the heat transport in nanofluid over a wedge (Falkner Skan flow) under viscous dissipation and thermal radiation over a wedge. The proper model formulation is carried out via similarity relations and empirical correlations of the nanofluids. After successful model transformation, numerical scheme (RK technique along with shooting technique) applied and furnished the results over the desired domain under varying effects of preemenant flow parameters. The results revealed that the velocity rises for opposing ([Formula: see text]) and assisting ([Formula: see text]) flows against [Formula: see text] and significant contribution of Ec and imposed thermal radiations (Rd number) observed in thermal performance of the nanofluid. The temperature declines by strengthen [Formula: see text] and optimum decrement is noted for opposing flow. Finally, a comparison is provided for various values of [Formula: see text] ([Formula: see text]) with previously published work under certain restrictions and found an excellent agreement.