[Clinico-endoscopic and morphometric characteristics of gastric and duodenal mucosa in children with dermatomyositis]. / Kliniko-éndoskopicheskaia i morfometricheskaia kharakteristika slizistoi obolochki zheludka i dvenadtsatiperstnoi kishki u detei s dermatomiozitom.

A total of 53 patients with dermatomyositis aged 4-14 with the disease duration of three months to eight years were under observation. Twenty seven patients complained of stomach-ache, II felt pain during palpation, 30 lost appetite. Electrogastrography revealed disorders in bioelectric activity of the stomach muscles in 99.9% of the patients. Endoscopic studies revealed lesions in the stomach and duodenum in all the patients, in 39 of them gastroduodenitis in the stage of exacerbation was diagnosed, in 7 erosion, in 3 peptic and duodenal ulcer. In 81.3% of the children during clinico-laboratory remission of dermatomyositis gastroduodenitis persisted at the stage of exacerbation. The vessels lying in the mucosa of the antral area of the stomach and duodenum underwent peculiar changes: arterial walls looked thickened, nuclei of the endothelial cells were enlarged, rounded up. One could observe infiltrates around the vessels consisting mainly of lymphocytes. Morphometric indices of the mucosa were also different in the antral area of the stomach and duodenum. Apparently, changes revealed in the gastric and duodenal mucosa of children with dermatomyositis occur due to vascular processes developing as a result of the main disease. This should be taken into consideration in the treatment of such children.

[The morphometric and immunohistochemical characteristics of the gastric and duodenal mucosa in systemic lupus erythematosus]. / Morfometricheskie i immunogistokhimicheskie osobennosti slizistoi obolochki zheludka i dvenadtsatiperstnoi kishki pri sistemnoi krasnoi volchanke.

Histological, morphometric, and immunohistochemical studies of biopsy specimens from the mucosa of the body and antral portion of the stomach, the bulb and descending portion of the duodenum were performed in 27 children with systemic lupus erythematosis (SLE) and in 12 with chronic gastroduodenitis. The inflammatory infiltrate from SLE patients was found to contain higher levels of young and mature fibroblasts than that from patients with chronic gastroduodenitis, mature fibroblasts being prevalent. The inflammatory changes in the gastric and duodenal mucosa were ascertained to be associated with the progression of SLE. In exacerbation of SLE, the walls of vessels (arterioles) exhibited immune complexes classified mainly as IgG and, to a lesser degree, as IgM. In remission, the luminescence of the vessels decreased. The serum level of immunoglobins did not correlate with their regional production in the gastric and duodenal mucosa.

[Treatment of multiple fractures of bones of the hand and finger phalanges in children]. / Lechenie mnozhestvennykh perelomov kostei kisti i falang pal'tsev u detei.

Results of treatment of 41 children are analysed. Early surgical treatment of the wounds, recovery of all the anatomical structures and closed reposition gave good and satisfactory results in most of the children.