Experimental study on compression of 216-W laser pulses below 2 ps at 1030 nm with chirped volume Bragg grating.

We report on the characterization of a high-power, chirped volume Bragg grating (CVBG) pulse compressor. It includes measurements of the CVBG's diffraction efficiency, beam profile, beam quality (M2 parameter), pulse spectrum, the CVBG's temperature, and the thermal lens. These parameters were monitored for a wide range of input laser powers and with different clamping forces applied on the CVBG. This analysis was performed with a CPA-based Yb:YAG thin-disk laser system operating at a wavelength of 1030 nm, a 92 kHz repetition rate, 2 ps pulse duration, and an average output power after compression of 216 W (270 W uncompressed), which is, to the best of our knowledge, the highest value reported to date using this pulse compression technique.

Laser-induced crystallization of anodic TiO2 nanotube layers.

In this study, crystallization of amorphous TiO2 nanotube (TNT) layers upon optimized laser annealing is shown. The resulting anatase TNT layers do not show any signs of deformation or melting. The crystallinity of the laser annealed TNT layers was investigated using X-ray diffraction, Raman spectroscopy, and high-resolution transmission electron microscopy (HRTEM). The study of the (photo-)electrochemical properties showed that the laser annealed TNT layers were more defective than conventional TNT layers annealed in a muffle oven at 400 °C, resulting in a higher charge recombination rate and lower photocurrent response. However, a lower overpotential for hydrogen evolution reaction was observed for the laser annealed TNT layer compared to the oven annealed TNT layer.

New observations on DUV radiation at 257†nm and 206†nm produced by a picosecond diode pumped thin-disk laser.

We report new observations on picosecond deep ultraviolet coherent beams generated in a CLBO as the fourth and fifth harmonics of a diode pumped high average power Yb:YAG thin disk laser operating at 77 kHz repetition rate at 1030 nm. The effects of the two-photon absorption were observed, e.g. the modification of phase matching conditions, lowering of the conversion efficiency. The fifth harmonic generation (4ω+1ω) was studied for different time delays between both pump beams and for the case of excess input power of the fundamental. The latter effect suggests a possibility of increasing DUV output at short crystals. The highest output power obtained at 257 nm was 7.6 W and 1 W at 206 nm. To our knowledge these DUV output powers rank among the highest for picosecond pulses at the repetition rate of the order of magnitude of 100 kHz.

Possible control of paternal imprinting of polymorphisms of the ADAM33 gene by epigenetic mechanisms and association with level of airway hyperresponsiveness in asthmatic children.

INTRODUCTION: ADAM33 is the candidate gene most commonly associated with asthma and airway hyperreactivity (AHR). AIM: The aim of this study was to determine whether level of AHR is associated with certain alleles or haplotypes of the ADAM33 gene in asthmatic children. METHODS: One hundred and nine asthmatic children and 46 controls from the general population were examined with spirometry before and after histamine and methacholine inhalation. All subjects were genotyped for single-nucleotide polymorphisms (SNPs) of the ADAM33 gene. Haplotypes were determined according to genotypes of the patient's parents. RESULTS: We found the three most frequent ADAM33 haplotypes (a1-3) were associated with the highest level of AHR to methacholine and histamine in 66% of asthmatic children. The paternally transmitted GGGCTTTCGCA haplotype was seen in 73.3% asthmatic children with serious AHR to methacholine challenge (paternal and maternal origin of haplotype 73.3% to 37.5, P=0.046) Significant differences in the relative frequency of paternal haplotypes with high levels of AHR to histamine were found (P=0.013). CONCLUSION: ADAM33 haplotypes (a1, a2, a3) are associated with severity of AHR and are significantly more often transmitted in the paternal line.