Developing a Prediction Model for Family Health in Families of Patients with Schizophrenia / 정신간호학회지

PURPOSE: The purpose of this study was to identify factors related to family health and develop a prediction model with an ability to explain family health in families of patients with schizophrenia.METHODS: A hypothesized model with twelve pathway forms was developed based on literature review. Family stress and social stigma were included as two exogenous variables; whereas family resilience, family empowerment, self-esteem, community integration, and family health were included as endogenous variables. Data were collected using a self-report questionnaire from 206 families of patients with schizophrenia living in Republic of Korea. Data were analyzed with PASW/WIN 18.0 and AMOS 18.0 programs.RESULTS: Social stigma had a negatively indirect and total effect on family health. Family resilience, self-esteem, and community integration had positive and direct and overall effects on family health.CONCLUSION: A prediction model for families of patients with schizophrenia is proposed and social stigma, family resilience, self-esteem, and community integration are presented as predicting factors for family health. Nursing interventions and support programs should be developed to overcome social stigma and improve family resilience, self-esteem, and community integration.

Differential Tissue-specific and Pathway-specific Anti-obesity Effects of Green Tea and Taeumjowitang, a Traditional Korean Medicine, in Mice

BACKGROUND: Traditional medicines have been leveraged for the treatment and prevention of obesity, one of the fastest growing diseases in the world. However, the exact mechanisms underlying the effects of traditional medicine on obesity are not yet fully understood. METHODS: We produced the transcriptomes of epididymal white adipose tissue (eWAT), liver, muscle, and hypothalamus harvested from mice fed a normal diet, high-fat-diet alone, high-fat-diet together with green tea, or a high-fat-diet together with Taeumjowitang, a traditional Korean medicine. RESULTS: We found tissue-specific gene expression patterns as follows: (i) the eWAT transcriptome was more significantly altered by Taeumjowitang than by green tea, (ii) the liver transcriptome was similarly altered by Taeumjowitang and green tea, and (iii) both the muscle and hypothalamus transcriptomes were more significantly altered by green tea than Taeumjowitang. We then applied integrated network analyses, which revealed that functional networks associated with lymphocyte activation were more effectively regulated by Taeumjowitang than by green tea in the eWAT. In contrast, green tea was a more effective regulator of functional networks associated with glucose metabolic processes in the eWAT. CONCLUSIONS: Taeumjowitang and green tea have a differential tissue-specific and pathway-specific therapeutic effect on obesity.

Dual effects of a mixture of grape pomace (Campbell Early) and Omija fruit ethanol extracts on lipid metabolism and the antioxidant defense system in diet-induced obese mice

BACKGROUND/OBJECTIVES: We investigated the effects of a combination of grape pomace (Vitis labrusca, Campbell Early) and Omija fruit (Schizandra chinensis, Baillon) ethanol extracts on lipid metabolism and antioxidant defense system in diet-induced obese mice. MATERIALS/METHODS: Forty male C57BL/6J mice were divided into four groups and fed high-fat diet (control group, CON) or high-fat diet added 0.5% grape pomace extract (GPE), 0.05% Omija fruit extract (OFE) or 0.5% GPE plus 0.05% OFE (GPE+OFE) for 12 weeks. RESULTS: In contrast to the GPE- or OFE-supplemented groups, the GPE+OFE group showed significantly lower body weight and white adipose tissue weights than the CON group. Moreover, GPE+OFE supplementation significantly decreased plasma total cholesterol and increased the plasma HDL-cholesterol/total-cholesterol ratio (HTR) compared to the control diet. The hepatic triglyceride level was significantly lower in the GPE+OFE and GPE groups by increasing beta-oxidation and decreasing lipogenic enzyme compared to the CON group. Furthermore, GPE+OFE supplementation significantly increased antioxidant enzyme activities with a simultaneous decrease in liver H2O2 content compared to the control diet. CONCLUSIONS: Together our results suggest that supplementation with the GPE+OFE mixture may be more effective in improving adiposity, lipid metabolism and oxidative stress in high-fat diet-fed mice than those with GPE and OFE alone.

Anti-carcinogenic effects of non-polar components containing licochalcone A in roasted licorice root

BACKGROUND/OBJECTIVE: Licorice has been shown to possess cancer chemopreventive effects. However, glycyrrhizin, a major component in licorice, was found to interfere with steroid metabolism and cause edema and hypertension. The roasting process of licorice modifies the chemical composition and converts glycyrrhizin to glycyrrhetinic acid. The purpose of this study was to examine the anti-carcinogenic effects of the ethanol extract of roasted licorice (EERL) and to identify the active compound in EERL. MATERIALS/METHODS: Ethanol and aqueous extracts of roasted and un-roasted licorice were prepared. The active fraction was separated from the methylene chloride (MC)-soluble fraction of EERL and the structure of the purified compound was determined by nuclear magnetic resonance spectroscopy. The anti-carcinogenic effects of licorice extracts and licochalcone A was evaluated using a MTT assay, Western blot, flow cytometry, and two-stage skin carcinogenesis model. RESULTS: EERL was determined to be more potent and efficacious than the ethanol extract of un-roasted licorice in inhibiting the growth of DU145 and MLL prostate cancer cells, as well as HT-29 colon cancer cells. The aqueous extracts of un-roasted and roasted licorice showed minimal effects on cell growth. EERL potently inhibited growth of MCF-7 and MDA-MB-231 breast, B16-F10 melanoma, and A375 and A2058 skin cancer cells, whereas EERL slightly stimulated the growth of normal IEC-6 intestinal epithelial cells and CCD118SK fibroblasts. The MC-soluble fraction was more efficacious than EERL in inhibiting DU145 cell growth. Licochalcone A was isolated from the MC fraction and identified as the active compound of EERL. Both EERL and licochalcone A induced apoptosis of DU145 cells. EERL potently inhibited chemically-induced skin papilloma formation in mice. CONCLUSIONS: Non-polar compounds in EERL exert potent anti-carcinogenic effects, and that roasted rather than un-roasted licorice should be favored as a cancer preventive agent, whether being used as an additive to food or medicine preparations.

Evaluation of Adiposity-Related Biomarkers as Metabolic Syndrome Indicators

Recent studies have suggested a relationship of the increased circulating adipokines and inflammatory cytokine, and the risk of metabolic syndrome (MetS). The objective of this study was to identify adiposity-related factors that reflect MetS in order to establish early intervention targets. We performed a cross-sectional study which included 108 MetS subjects and 91 controls. Blood adiponectin, leptin, vascular-, and intercellular adhension molecules (VCAM, ICAM), monocyte chemoattractant protein 1 (MCP1), high-sensitivity C-reactive protein (hsCRP), oxidized LDL (oxLDL), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) were measured. The correlation analysis indicated that the MetS score (sum of the number of MetS risk factors) had an inverse relationship with adiponectin (p < 0.0001), and positive correlations with leptin (p < 0.05), ICAM (p < 0.01), MCP1 (p < 0.05), oxLDL (p < 0.05), TNF-alpha (p < 0.0001), IL-6 (p < 0.05) and hsCRP (p < 0.01). In multivariate logistic regression analyses, plasma triglyceride (TG) was independently associated with adiponectin, ICAM and TNF-alpha with the standardized beta coefficients of -0.213, 0.197, and 0.193, respectively. Plasma HDL-cholesterol was independently associated with ICAM and hsCRP with the standardized beta coefficients of -0.150 and -0.173. Adiponectin, TNF-alpha, and hsCRP were the most proximate markers reflecting MetS. Among MetS components, TG and HDL-cholesterol concentrations displayed the relationship with inflammatory markers measured in this study.

High fat diet-induced obesity leads to proinflammatory response associated with higher expression of NOD2 protein

Obesity has been reported to be associated with low grade inflammatory status. In this study, we investigated the inflammatory response as well as associated signaling molecules in immune cells from diet-induced obese mice. Four-week-old C57BL mice were fed diets containing 5% fat (control) or 20% fat and 1% cholesterol (HFD) for 24 weeks. Splenocytes (1 x 10(7) cells) were stimulated with 10 microg/mL of lipopolysaccharide (LPS) for 6 or 24 hrs. Production of interleukin (IL)-1beta, IL-6, and TNF-alpha as well as protein expression levels of nucleotide-binding oligomerization domain (NOD)2, signal transducer and activator of transcription (STAT)3, and pSTAT3 were determined. Mice fed HFD gained significantly more body weight compared to mice fed control diet (28.2 +/- 0.6 g in HFD and 15.4 +/- 0.8 g in control). After stimulation with LPS for 6 hrs, production of IL-1beta was significantly higher (P = 0.001) and production of tumor necrosis factor (TNF)-alpha tended to be higher (P < 0.064) in the HFD group. After 24 hrs of LPS stimulation, splenocytes from the HFD group produced significantly higher levels of IL-6 (10.02 +/- 0.66 ng/mL in HFD and 7.33 +/- 0.56 ng/mL in control, P = 0.005) and IL-1beta (121.34 +/- 12.72 pg/mL in HFD and 49.74 +/- 6.58 pg/mL in control, P < 0.001). There were no significant differences in the expression levels of STAT3 and pSTAT3 between the HFD and the control groups. However, the expression level of NOD2 protein as determined by Western blot analysis was 60% higher in the HFD group compared with the control group. NOD2 contributes to the induction of inflammation by activation of nuclear factor kappaB. These findings suggest that diet-induced obesity is associated with increased inflammatory response of immune cells, and higher expression of NOD2 may contribute to these changes.

5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion

A variety of benzylidenethiazole analogs have been demonstrated to inhibit 5-lipoxygenase (5-LOX). Here we report the anti-atherogenic potential of 5-(4-hydroxy-2,3,5-trimethylbenzylidene) thiazolidin-2,4-dione (HMB-TZD), a benzylidenethiazole analog, and its potential mechanism of action in LDL receptor-deficient (Ldlr-/-) mice. HMB-TZD Treatment reduced leukotriene B4 (LTB4) production significantly in RAW264.7 macrophages and SVEC4-10 endothelial cells. Macrophages or endothelial cells pre-incubated with HMB-TZD for 2 h and then stimulated with lipopolysaccharide or tumor necrosis factor-alpha (TNF-alpha) displayed reduced cytokine production. Also, HMB-TZD reduced cell migration and adhesion in accordance with decreased proinflammatory molecule production in vitro and ex vivo. HMB-TZD treatment of 8-week-old male Ldlr-/- mice resulted in significantly reduced atherosclerotic lesions without a change to plasma lipid profiles. Moreover, aortic expression of pro-atherogenic molecules involved in the recruitment of monocytes to the aortic wall, including TNF-alpha , MCP-1, and VCAM-1, was downregulated. HMB-TZD also reduced macrophage infiltration into atherosclerotic lesions. In conclusion, HMB-TZD ameliorates atherosclerotic lesion formation possibly by reducing the expression of proinflammatory molecules and monocyte/macrophage recruitment to the lesion. These results suggest that HMB-TZD, and benzylidenethiazole analogs in general, may have therapeutic potential as treatments for atherosclerosis.

Effects of Paters' Duola Touch during Labor on the Paternal Attachment and Role Confidence to Neonate and Couple Attachment / 여성건강간호학회지

PURPOSE: The purpose of this study was to identify the effects of paters' doula touch during labor on paternal attachment and role confidence to neonate and couple attachment. METHODS: The participants were 60 couples of laboring woman and her husband who were hospitalized from May 2010 to december 2010. Among 60 couples, 30 couples were assigned to an experimental group and the other 30 couples to a control group. All of them had any other complications of pregnancy. During one month, the paters' duola touch was applied to the experimental group of 32~42 gestation once a week and be in labor. Data were analyzed using SPSS/WIN 14.0 Win program. RESULTS: The scores for role confidence to neonate and couple attachment in the experimental group were significantly higher than those for the control group. The paternal attachment score of the experimental group was higher than that of the control group, but it was not significant. CONCLUSION: From these findings, it is concluded that paters' doula touch during pregnancy and labor can be helpful to improve attachment to the neonate and his/her spouse.

The Effects of Relaxation Therapy on Anxiety and Stress of Pregnant Women with Preterm Labor / 여성건강간호학회지

PURPOSE: The purpose of this study was to identify the effect of relaxation therapy on state anxiety, preterm labor stress, blood pressure, skin temperature, pulse rate of pregnant women with preterm labor and heart rate of their babies. METHODS: The participants were 55 pregnant women with preterm labor who hospitalized from May, 2009 to January, 2010. 29 participants were assigned to experimental group and the other 26 participants to control group. All of them were not have any other complications except preterm labor. The relaxation therapy was applied to the experimental group for 5 days. Data were analyzed by the SPSS/WIN 14.0 program. RESULTS: The state anxiety score and the preterm labor stress score of experimental group were statistically significant lower than those of control group. In addition, the systolic and diastolic blood pressure, pulse rate of experimental group were statistically lower than those of control group. The skin temperature of experimental group was higher than that of control group. However, the fetal heart rate of experimental group was not statistically significant lower than fetal heart rate of control group. CONCLUSION: From these findings, it is concluded that relaxation therapy may be an effective nursing intervention for pregnant women with preterm labor.

Effect of Young Barley Leaf on Lipid Contents and Hepatic Lipid-Regulating Enzyme Activities in Mice Fed High-Fat Diet

This study was conducted to investigate the effects of powdered young barley leaf and its water extract on body weight and lipid metabolism in high-fat fed mice. Male mice were divided into normal group, high-fat (HF) group, highfat group supplemented with powdered young barley leaf (HF-YBL) and high-fat group supplemented with water extract of the powdered young barley leaf (HF-WYBL). The powdered young barley leaf or its water extract was added to a standard diet based on 1% dried young barley leaf (1 g YBL/100 diet and 0.28 g WYBL/100 g diet) for 8 weeks. Supplementation of YBL and WYBL significantly reduced body weight and epididymal adipose tissue weight in highfat fed mice. Food intake and daily energy intake were significantly lower in the YBL group than in the HF group. After 8 weeks, plasma triglyceride and cholesterol concentrations were significantly higher in the HF group than in the Normal group; however, both YBL and WYBL significantly lowered those of the high-fat fed mice. The ratio of HDL-cholesterol/ total cholesterol of the YBL and WYBL groups were significantly elevated compared to that of HF group. Both YBL and WYBL significantly increased fecal excretion of triglyceride in high-fat fed mice, whereas they did not affect fecal cholesterol concentration. The triglyceride levels of liver, adipose tissue and heart were significantly lower in the YBL and WYBL groups than in the HF group. Supplementation of WYBL also lowered the kidney triglyceride and heart cholesterol concentrations compared to those of HF group. Hepatic lipid regulating enzyme activities, fatty acid synthase, HMG-CoA reductase and acyl-coenzyme A: cholesterol acyltransferase, were significantly lower in the YBL and WYBL groups than in the HF group. Accordingly, these results suggest that YBL and WYBL improve plasma and organ lipid levels partly by increasing fecal lipid excretion and inhibiting fatty acid and cholesterol biosynthesis in the liver.

A Study of Educational Need, Attitude and Knowledge toward Menopause in Middle-aged Women / 여성건강간호학회지

PURPOSE: The purpose of this study was to investigate educational needs, knowledge and attitude towards menopause in middle-aged women METHOD: The research design was a descriptive study. The subjects of this study were 231 middle-aged women. Data was collected from a structured questionnaire from October 2 to November 30, 2007. RESULT: The score of educational needs towards menopause was relatively high at 3.83/5. The score of educational needs related to 'Osteoporosis'(3.99 score), 'Cardiovascular disease' (3.91 score), and 'Hormone replacement therapy'(3.87 score) was relatively high. The score of knowledge towards menopause was relatively low at 17.28/30. The score of attitude towards menopause was neutral at 2.3/4. The relationship between knowledge and attitude towards menopause revealed a negative significant correlation (r=-.194, p=.003). The relationship between knowledge and educational needs towards menopause revealed a positive significant correlation (r=0.275, p<.0001). The degree of educational needs of women before menopause is higher than in menopausal women. CONCLUSION: There is a need to develop a continuing educational program according to age and menopause condition. Specialists (Nurses) must give information about menopause for a positive attitude toward menopause.

Internalization of the Sociocultural Attitudes, Body Shape Satisfaction, Anger and Eating Attitudes in College Women / 여성건강간호학회지

PURPOSE: The descriptive study was designed to examine the relationship of eating attitudes to the internalization of sociocultural attitudes, body shape satisfaction, anger and anger expression in college women. METHOD: 247 women were recruited from one college located in Seoul, Korea. The instruments used were the Internalization subscale of SATAQ-3R, BSQ for body shape satisfaction, Spielberger's state trait anger expression inventory-Korean version for anger and anger expression, and the Eating Attitude Test(EAT-26) for eating attitudes. RESULTS: The score of EAT significantly correlated with internalization, state anger, body shape satisfaction, and anger expression except trait anger. The significant predictors of eating attitudes in college women were body shape satisfaction and anger expression, explaining 55% of the variance in eating attitudes. CONCLUSION: This study showed that body shape satisfaction is an important predictor for an eating disorder. Therefore, various programs for cognitive changes correcting the understanding about body and weight need to be developed in the future.

The Relation of Self-reported Adult Attachment Style, Perceived Parental Rearing Style and Anger in Undergraduate Students / 기본간호학회지

PURPOSE: This study was done to examine the relation of self-reported adult attachment style, perceived parental rearing styles and anger in undergraduate students. METHOD: The six hundred and fifty undergraduate students participating in this descriptive correlational design study were conveniently sampled from K University and S College located in Seoul, Korea. The instruments were Spielberger's state-trait anger expression inventory - Korean version(Chon, Han, Lee & Spielberger, 1997), the instrument for measuring attachment styles by Hazen and Shaver (1987), and Hong's instrument for measuring parental rearing style(2001). Data were analyzed by descriptive statistics, t-test, chi-square-test, ANOVA, and cluster analysis using pc-SAS(version 8.0e) program. RESULTS: The mean scores for trait anger and anger-in were higher in undergraduate students with insecure and ambivalent attachment style compared to students with a secure attachment style. The mean score for anger-control was highest in undergraduate students with a secure attachment style. The parental rearing styles by cluster analysis were grouped as Neglect, Permissive, Democratic, and Protective-control. The mean scores for trait anger, anger-in, and anger-out were higher in undergraduate students with 'Neglect' parental rearing style than in those with 'Democratic' and 'Protective-control' rearing styles. CONCLUSION: Trait anger and anger expression might be related to an attachment style and/or a parental rearing style.

A Study of Stress of Middle-aged Women with a Senior in High School / 여성건강간호학회지

PURPOSE: The purpose of this study was to investigate the stress caused by having a senior in high school preparing for the college entrance examination, and coping methods of middle aged women in order to have a high quality of life. METHOD: The subjects of this study were 410 middle aged women. The data were collected by a structured questionnaire during September 5 to October 26, 2005. RESULT: The respondents' scores of stress were relatively low. The scores of stress perception related to 'studies record inactivity', 'a bad feeling because their sons and daughters are lazy', and worries about fatigue and health of their sons and daughters' were relatively high. The scores of the coping method related to 'affirmative thought and conduct', and 'sincerity it in the senior in high school student' were relatively high. In subjects with a higher degree(score > or = 3) of stress caused by the senior student in high school the scores of coping methods related to 'projection', 'evasion', and 'perseverance' were relatively higher than the scores of coping methods of subjects with a lower degree (score < 3) of stress. CONCLUSION: Based on the findings of this study, we should develop an integrated support program for middle-aged women. A place must be made where mothers will be able to discuss the education of their children such as on-line group community by mothers.

A Study on Knowledge, Attitude, and Experience in Sex and Sexual Autonomy of College Students / 여성건강간호학회지

PURPOSE: The purpose of this study was to measure knowledge, attitude, experience of sex, sexual autonomy and the need of sex education of college students in order to provide sex information. METHOD: The subjects of this study were 356 college students. The data were collected from October 26 to December 5, 2003 by using a structured questionnaire. RESULT: The respondents' score of sexual knowledge was relatively low as 53.7 mean score on the basis of 100. However, the scores of sexual knowledge related to masturbation, induced abortion, and contraception were relatively high. The respondents' score of sexual attitude was 3.09. The respondents' score of sexual autonomy was 3.89. The percentage of subjects that experienced sexual intercourse was 41.6% and there was a difference between the gender. There was a positive correlation between sexual knowledge and sexual autonomy and between sexual knowledge and sexual attitude. There were significant differences in the sexual knowledge, sexual attitude and sexual autonomy depending upon the experience of coitus. The respondents expressed the need of sex education in college. CONCLUSION: An integrated sex education program should be developed and contents must have a concrete and honest education which is appropriate to college students.

Cystic Adenomyoepithelioma of the Breast: A Case Report

Adenomyoepithelioma of the female breast is a rare tumor. With rare exceptions, the tumor is uniformly solid. We describe a large grossly cystic adenomyoepithelioma in a 67-year-old female. The tumor was histologically benign. The characteristic microscopic finding was the proliferation of rounded tubules lined by both epithelial and myoepithelial cells. Immunohistochemical findings confirmed the presence of two cell population.

Affecting Factors of Deviant Behaviors of Korean High School Students / 아동간호학회지

PURPOSE: The purpose of this study is to analyze the factors affecting Deviant Behaviors of Korean High school Students. METHOD: Data was collected from October 8 to 31, 2002. The subjects for this study were 697 Korean High school Students(boys 347, girls 350), recruited from two High School located in Seoul. Data collection was conducted through the use of 6 Questionnaire that modified by the investigator. The data was analyzed by the SPSS win 10.0 program using Descriptive statistics, Pearson Correlation coefficient and stepwise multiple regression. RESULT: 1) The mean of total item score the Deviant Behaviors scales was 1.59, which was slightly low. 2) There was a significant correlation between Deviant Behaviors, Type A Personality, Aggression, Impulsivity, Stress and Social Support(gamma= .11 ~ .65, p < .001), but It was no significant correlation Type A Personality and Stress(gamma= -.01). 3) Stepwise multiple regression analysis showed that (1) Impulsivity, Social Support and Type A Personality were the predictors of Deviant Behaviors and account for 18.6% of the variance in Deviant Behaviors. (2) Impulsivity account for 3.6% of the variance in Deviant Behaviors in Subjects with a lower degree of score the Deviant Behaviors. Impulsivity and Social Support account for 23.2% of the variance in Deviant Behaviors in subjects with higher degree of score the Deviant Behaviors. (3) Impulsivity account for 18.3% of the variance in Deviant Behaviors in High school girls (n=350). Impulsivity and Social Support account for 20.1% of the variance in Deviant Behaviors in High school boys (n=347). CONCLUSION: Impulsivity and Social Support account for Deviant Behaviors of High school Students. Therefore it is necessary to develop nursing intervention to reduce the level of Impulsivity, to increase the Social Support in order to decrease the Deviant Behaviors.

A Predictive Model Comparison by Sex for Alcohol Consumption Behavior among Korea University Students / 간호학회지

The purpose of this study was designed to develope and test the structural model that explains alcohol consumption behaviors among university students in Republic of Korea. The hypothetical model was constructed on the basis of the literature review and Pender's Health promotion model. Data was collected from questionnaires from 512 university students in Republic of Korea, from August to September, 2000. The reliability of instruments was adequate (Cronbach's alpha= .69-.90). Data analysis was done with SAS 6.12 for descriptive statistics and LISREL 8.13 program for covariance structural analysis. The results are as follows;1. The overall fit of the hypothetical model to the data was moderate. Thus it was modified by male and female models.2. The revised model has become parsimonious and had a better fit to the empirical data (male: x2=87.21 p=.00, GFI=.97, AGFI= .94, NFI=.99, NNFI=1.0, CN=619.17, female: x2=49.29 p=.31, GFI=.45, AGFI= .95, NFI=.99, NNFI=1.0, CN=370.02).3. Self-efficacy was most significant factor and personality of novelty seeking, reward compensation, alcohol expectancy and drinking attitude have significant effects on male alcohol consumption behavior. 4. Personality of novelty seeking was most significant factor and personality of harm avoidance, friend influence, self-efficacies, alcohol expectancy and drinking attitude have significant effects on female alcohol consumption behavior.

A Study on Eating Disorder, Depression and Body Dissatisfaction of Middle Aged Women / 여성건강간호학회지

The purpose of this study was to investigate the relationship between eating disorders, depression, and body dissatisfaction of middle aged women. Data was collected from June 1 to June 30, 1999 by means of a structured uestionnaire. The subjects for this study were 99 middle aged women between the ages of 35 and 59, recruited from Seoul, Kyungido. The instruments were the BDI(Beck Depression Inventory) developed by Beck(1973), Eating Disorder Inventory(1997) developed by Garner & Garfinkel, Halm, Falk& Schwartz, Shin Mi Young. The instruments were the Body Dissatisfaction(1997) developed by Garner, Olstead & Polivy, Han osoo, yoo hee jung, shin Mi Young. The data was analyzed by the SPSS/PC program using frequency, percentage, mean, standard deviation, t-test, ANOVA and Pearson correlation coefficient.The results of this study are as follows 1. The mean body weight and height of the subjects were 57.49kg, 158.62cm.2. Depending upon BMI, the obesity subjects were 18.2% and the rest(81.8%) were under weight or normal. More than 70% of the normal weight subjects(71 subjects) perceived their weight as overweight.3. The total mean scores of anorexia nervosa were higher than bulimia nervosa. The total mean scores of eating disorders was 2.13.4. The total mean scores of depression was 1.50.5. The total mean scores of body dissatisfaction was 3.30. 6. There was a positive correlation between depression and eating disorders(r= .267, p<0.01)and, between body dissatisfaction and eating disorders(r=.273, p<0.01).There was not a significant correlation between depression and body dissatisfaction.According to the present study eating disorders in middle aged women developed because of the tendency to have negative perceptions of their bodies.

Comparison of Dietary Intakes, Smoking Status, Plasma Lipids, Lipoprotein (a) and Antioxidant Nutrients in Patients With Coronary Heart Disease and Healthy Controls

BACKGROUND: Hyperlipidemia has been known as an independent risk factor in the develop-ment of coronary artery disease. This study was carried out to compare nutrient intakes, smo-king status, antioxidant vitamins, and plasma lipids in patients with coronary heart disease (CHD) and in normal healthy subjects among Korean population in Taegu. Possible causes of this dis-ease in patients are discussed. METHODS: Anthropometric assessments included mean intakes of nutrients, and the levels of plasma lipids (apolipoprotein [Apo] A - I, Lipoprotein [Lp] [a]), and antioxidant vitamins (such as vitamins A and E) were measured in female and male subjects with CHD against healthy con-trols. RESULTS: Dietary cholesterol and fat intakes were significantly higher in CHD groups in men and women. Total plasma cholesterol, LDL-C, triglyceride, thiobarbituric acid reactive subst-ance (TBARS), atherogenic index and Lp (a) levels were significantly higher in CHD patients than in the normal group in both men and women. Apo A-I, HDL-C and vitamin E levels were lower in CHD patients than in the normal group. The number of smokers was higher in CHD patients than in the normal group in both sexes of subjects. CONCLUSION: High fat and high cholesterol intakes seemed to be a major factor for the hyperlipidemia in the CHD patients. Their abnormal lipoprotein profile, which appeared in pati-ent plasma, corresponded well to dietary intake patterns. However, long term studies are need-ed to investigate the effects of smoking on lipid metabolism in CHD patients among the Korean population.