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3.
J Am Acad Dermatol ; 52(2 Suppl 1): 17-9, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15692505

RESUMO

Dermatomyositis is an autoimmune condition that results in significant morbidity and mortality through effects on muscle and skin. Corticosteroids are the mainstay of therapy of dermatomyositis, and severe morbidity and mortality occurs in part through the known long-term side effects of chronic steroid use. In addition, dermatomyositis is commonly associated with underlying malignancy, and high-dose steroids may adversely impair treatment of these malignancies. We describe the first use of rapamycin in a young patient with dermatomyositis.


Assuntos
Dermatomiosite/tratamento farmacológico , Imunossupressores/uso terapêutico , Sirolimo/uso terapêutico , Adulto , Doenças Autoimunes/tratamento farmacológico , Feminino , Glucocorticoides/administração & dosagem , Humanos , Hipertrigliceridemia/induzido quimicamente , Imunossupressores/efeitos adversos , Prednisona/administração & dosagem , Sirolimo/efeitos adversos
4.
Dermatol Surg ; 30(12 Pt 2): 1550-2, 2004 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15606838

RESUMO

BACKGROUND: Although it has been established that basal cell carcinoma is an uncommon diagnosis in black patients, the morpheaform subtype is very rare among these individuals. OBJECTIVE: The objective is to present two cases of morpheaform basal cell carcinoma in African-American patients. METHODS: This is a case series and a literature review using the Ovid Medline Database. Key words used in the search include "basal cell carcinoma," "African American," "black," "African," "negros," "morpheaform," "sclerosing," "fibrosing," and "scar-like basal cell carcinoma." The Ovid Medline Database was searched from 1966 to present and was restricted to the English language. RESULTS: A review of the Emory Dermatology clinic charts from 1989 to 2004 revealed two black patients with morpheaform basal cell carcinomas. CONCLUSIONS: Although extremely rare, morpheaform pattern basal cell carcinoma must be considered in the differential diagnosis for black patients presenting with nonhealing lesions.


Assuntos
Carcinoma Basocelular/diagnóstico , Neoplasias Cutâneas/diagnóstico , Idoso , Idoso de 80 Anos ou mais , População Negra , Carcinoma Basocelular/genética , Carcinoma Basocelular/patologia , Diagnóstico Diferencial , Feminino , Humanos , Pessoa de Meia-Idade , Nariz , Neoplasias Cutâneas/genética , Neoplasias Cutâneas/patologia
5.
J Clin Microbiol ; 42(4): 1813-7, 2004 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15071058

RESUMO

We report two cases of lower-extremity furunculosis caused by Mycobacterium mageritense. Both patients were patrons of the same nail salon, where they received footbaths prior to pedicures. M. mageritense bacteria isolated from two whirlpool footbaths were determined to be closely related to the patient isolates by pulsed-field gel electrophoresis.


Assuntos
Indústria da Beleza , Furunculose/microbiologia , Infecções por Mycobacterium/microbiologia , Mycobacterium/isolamento & purificação , Unhas , Adulto , Eletroforese em Gel de Campo Pulsado , Feminino , Humanos , Hidroterapia , Pessoa de Meia-Idade , Mycobacterium/genética
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