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1.
Patholog Res Int ; 2010: 292606, 2010 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-21152176

RESUMO

Extraovarian granulosa cell tumor (GCT) is a very uncommon tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge. A 54 years old female patient presented with a mass and acute pain in abdomen. Exploratory laparatomy revealed hemoperitoneum with a large mesenteric mass measuring 13 × 12 cm in size, showing extensive areas of haemorrhages. Histopathological examination of the excised mass showed features of adult-type GCT. As the patient had a history of hysterectomy with bilateral salpingo-oophorectomy 10 years ago for ''leiomyoma" with no evidence of GCT of the ovary in the histopathology report, a diagnosis of extraovarian GCT was made. A diagnosis of extraovarian GCT should be carried out after excluding any previous history of GCT of the ovary. Tumor rupture with haemoperitoneum is a well-known complication of GCT. Extraovarian GCT is a rare tumor with only 10 cases reported in literature. The case is presented for its rarity.

2.
Acta Cytol ; 54(4): 635-9, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20715670

RESUMO

BACKGROUND: Carotid body tumors (CBTs) constitute the most common extraadrenal paragangliomas. Many lesions diagnosed as CBTs by fine needle aspiration (FNA) cytology are clinically unsuspected. The main differential diagnosis is a thyroid neoplasm. The location of the mass in the lateral neck with prolonged history, hemorrhagic FNA and cytologic features resembling the endocrine neoplasm help in arriving at a suggestive diagnosis of paraganglioma. CASE: A 32-year-old male presented with left-sided facial palsy and swelling in the left side of the neck of 8 months' duration. The FNA sample was hemorrhagic and showed loosely arranged groups and acini formed by round to oval cells. A diagnosis of CBT was suggested. It was supplemented by additional noninvasive methods, such as ultrasonography of the neck region with color Doppler, computed tomography and magnetic resonance imaging of the brain, which also revealed a neoplasm suggestive of carotid body tumor in the right side of the neck and neoplastic lesion in the left cerebellopontine angle, suggestive of paraganglioma. CONCLUSION: FNA, with the other noninvasive radiologic investigations, plays an important role in the diagnosis of CBT. We present this case of multiple paragangliomas for its unusual presentation and FNA diagnosis.


Assuntos
Neoplasias Encefálicas/diagnóstico , Tumor do Corpo Carotídeo/diagnóstico , Paralisia Facial/diagnóstico , Neoplasias de Cabeça e Pescoço/diagnóstico , Adulto , Biópsia por Agulha Fina , Tumor do Corpo Carotídeo/complicações , Paralisia Facial/etiologia , Neoplasias de Cabeça e Pescoço/complicações , Humanos , Imageamento por Ressonância Magnética , Masculino , Neoplasias Primárias Múltiplas , Tomografia Computadorizada por Raios X , Ultrassonografia Doppler em Cores
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