RESUMO
Penile urethral injury may be associated with cavernosal rupture due to distractive force during coitus. Non-coital penile injury due to direct blow to the penis causing penile urethral and cavernosal rupture is rare. Definite management of urethral injury in such cases can be deferred as extent of devitalised tissue can be deceptive in acute conditions.
Assuntos
Hematoma/diagnóstico por imagem , Pênis/lesões , Pênis/cirurgia , Ruptura/cirurgia , Uretra/lesões , Uretra/cirurgia , Hematoma/etiologia , Hematoma/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Pênis/diagnóstico por imagem , Ruptura/diagnóstico por imagem , Resultado do Tratamento , Ultrassonografia , Uretra/diagnóstico por imagem , Cateterismo Urinário , Ferimentos não Penetrantes , Adulto JovemRESUMO
OBJECTIVES: The prevalence of urolithiasis is increasing worldwide. Diabetes mellitus (DM) is characterized by insulin resistance, which increases the risk of kidney stone formation. Adiponectin is an insulin-sensitizing and anti-inflammatory cytokine, which is known to improve glucose tolerance and insulin resistance in humans. The association of insulin and adiponectin with kidney stones is not clear. Hence, the present study aim to assess the serum levels of adiponectin and insulin resistance in DM patients with urolithiasis in comparison to those without. METHODS: This study involved two groups, group A consisted of 30 patients with DM and urolithiasis, and group B consisted of 30 patients with DM but without urolithiasis (control group). Biochemical parameters studied were serum adiponectin, insulin, glucose, urea, creatinine, and 24 hours urinary calcium and phosphate. RESULTS: The serum adiponectin level was significantly increased in the diabetic urolithiasis cases (group A) compared to the control group (group B). The levels of 24 hours urine calcium and phosphorus were also significantly increased in group A. There was no significant difference in serum insulin and homeostasis model assessment of insulin resistance between the two groups. A negative correlation was seen between serum adiponectin and insulin among the cases (r = -0.368 and p = 0.045). CONCLUSIONS: We found that serum adiponectin levels are increased in patients with DM and urolithiasis.