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1.
EClinicalMedicine ; 68: 102440, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38333539

RESUMO

Background: The Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) describes three primary avoidant/restrictive food intake disorder (ARFID) subtypes including sensory sensitivity, lack of interest in food or eating, and fear of aversive consequences. Studies exploring these subtypes have yielded varying results. We used latent class analysis (LCA) based on the psychopathology of ARFID in a sample of children and adolescents to empirically identify classes. Methods: We carried out a surveillance study of ARFID in collaboration with the British Paediatric Surveillance Unit (BPSU) and the Child and Adolescent Psychiatry Surveillance System (CAPSS) in the United Kingdom and the Republic of Ireland from 1st of March 2021 to 31st of March 2022. Paediatricians and child and adolescent psychiatrists were contacted monthly to report newly diagnosed cases of ARFID electronically and complete a detailed clinical questionnaire. Cases aged 5-18 years were included. LCA was performed specifying 1-6 classes and likelihood-based tests for model selection. The Bayesian Information Criterion (BIC), the Akaike Information Criterion (AIC) and the Sample-Size Adjusted BIC were used to determine the most parsimonious model. Analysis of variance (ANOVA) and χ2 tests were used to compare the characteristics of the identified classes. A multinomial logistic regression (MLR) was performed to investigate predicting factors for the latent classes. Findings: We identified 319 children and adolescents with ARFID. LCA revealed four distinct classes which were labelled as Fear subtype, Lack of Interest subtype, Sensory subtype, and Combined subtype. The probability of being classified as these were 7.2% (n = 23), 25.1% (n = 80), 29.5% (n = 94) and 38.2% (n = 122), respectively. Age at diagnosis, sex, weight loss, distress associated with eating, and autism spectrum disorder diagnosis were identified as predictors of class membership. Interpretation: LCA identified four different classes in a sample of children and adolescents with ARFID. The Combined Subtype, a mixed presentation was the most common. The other three classes resembled the subtypes described in the literature. Clinicians should be aware of these different presentations of ARFID as they may benefit from different clinical interventions. Funding: This study was funded by the Former EMS Ltd (charity number 1098725, registered October 9th 2017).

2.
Br J Hosp Med (Lond) ; 81(6): 1-8, 2020 Jun 02.
Artigo em Inglês | MEDLINE | ID: mdl-32589532

RESUMO

Anorexia nervosa is an eating disorder with peak onset in adolescence, which carries the highest mortality rate of all psychiatric illnesses. It is commonly comorbid with other physical and mental health problems, yet training on management of people with eating disorders and working knowledge of clinicians working with underweight adolescents is inconsistent. This review of anorexia nervosa in adolescents provides an overview of the presentation, aetiology and treatment of this disorder, with a particular focus on the assessment and management of physical health risks, including refeeding syndrome.


Assuntos
Anorexia Nervosa/fisiopatologia , Adolescente , Anorexia Nervosa/epidemiologia , Anorexia Nervosa/psicologia , Anorexia Nervosa/terapia , Arritmias Cardíacas/fisiopatologia , Índice de Massa Corporal , Bradicardia/fisiopatologia , Desidratação/fisiopatologia , Diagnóstico Precoce , Intervenção Médica Precoce , Humanos , Hipotermia/fisiopatologia , Incidência , Prognóstico , Síndrome da Realimentação/diagnóstico , Síndrome da Realimentação/terapia , Reino Unido/epidemiologia , Desequilíbrio Hidroeletrolítico/fisiopatologia
3.
Psychopathology ; 53(2): 74-83, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32375148

RESUMO

Schizophrenia patients frequently display an array of abnormal bodily phenomena (ABPs). There is literature to suggest that the presence of ABPs may be representative of a fundamental disruption of the embodied and prereflexive state of selfhood and hence be relevant for the development of schizophrenia spectrum disorders. ABPs have been considered as trait features of vulnerability to psychosis and may have value as potential markers for early detection, target symptoms for prevention and predictors of clinical outcomes. This longitudinal cohort study aimed to explore: (1) the prevalence of ABPs in first episode psychosis, (2) their longitudinal stability, (3) how ABPs compare with data from patients with enduring psychosis, and (4) how aspects of disorders of self-experience (DSEs) and ABPs and the corresponding instruments relate to each other. Sixteen patients were recruited from an early intervention in psychosis service. They were assessed with a series of structured and semi-structured interviews at point of entry, after 6 months and 12 months of follow-up. A variety of ABPs and DSEs were displayed in all study subjects, associated with high levels of core psychotic symptoms and reduced with treatment over time. Compared with findings of both acute and chronic schizophrenia patients, the prevalence of ABPs seems to be representative of severity and acuteness of the illness. Two factors were identified with stable trait characteristics and might be of predictive value for the course of the illness. Further studies with bigger samples are needed to further test the value of ABPs as early markers of detection and predictors of clinical course. The association between DSEs and ABPs warrants further investigation.


Assuntos
Transtornos Psicóticos/complicações , Adulto , Estudos de Coortes , Feminino , Humanos , Estudos Longitudinais , Masculino , Transtornos Psicóticos/diagnóstico , Adulto Jovem
4.
J Adolesc Health ; 66(2): 144-156, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31771922

RESUMO

PURPOSE: The objective of the study was to examine (1) the effect of restrictive eating disorders (EDs) on growth and pubertal development in children and young people (CYP) and (2) potential reversibility of this with recovery and associated factors. EDs can impact growth and puberty in CYP, but reports have conflicted over effect on height and permanence of growth impairment and pubertal delay. METHODS: This is a systematic review and meta-analysis, searching PubMed, EMBASE, PsycINFO, and Web of Science from May 31, 2018, to inception. We included observational studies or systematic reviews regarding growth and puberty in EDs in CYP aged <18 years or in studies reporting outcomes in adults known to have had an ED under age 18 years. Cross-sectional studies were pooled for meta-analysis for effects on height. RESULTS: A total of 27 studies were included. Growth and pubertal delay were commonly reported, but evidence for catch-up growth found in the majority. However, catch-up growth was not seen in all and may be suboptimal. Meta-analysis of 459 subjects (213 with anorexia nervosa and 246 controls) found no significant difference in height at baseline, with weighted mean difference -.13 cm (95% CI -2.64 to 2.38 cm; p = .9; I2 = 68.5%). Younger age and longer duration of illness are potential risks for growth delay; weight gain appears protective for catch-up growth. Findings are primarily generalisable to females, given limited data on males. CONCLUSIONS: CYP with restrictive EDs are at risk of growth impairment and pubertal delay, though potentially reversible. Attention to growth in EDs is important, especially in the young. Weight restoration should be encouraged to avoid adverse effects and allow opportunity for catch-up.


Assuntos
Transtornos da Alimentação e da Ingestão de Alimentos/complicações , Transtornos do Crescimento/etiologia , Puberdade , Adolescente , Adulto , Anorexia Nervosa , Estatura , Peso Corporal , Criança , Estudos Transversais , Feminino , Humanos , Masculino , Aumento de Peso
5.
Evid Based Ment Health ; 22(1): 23-25, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30665986

RESUMO

Training in communication skills is a vital part of medical education worldwide and essential for psychiatrists, with poor communication often cited as a key contributing factor in healthcare complaints. Simulation training is a rapidly developing educational modality, and educationalists need to be aware of its possible uses and pitfalls in teaching communications skills in psychiatry. By exploring the advantages and disadvantages of the use of simulation training as a method of teaching communication skills in psychiatry, this article demonstrates a clear consensus in the literature that, while there are a number of difficulties to be overcome in simulation training, these are outweighed by the clear educational gains. In areas where resources are limited, there are suitable variations of simulation training which can be employed. Simulation training can facilitate teaching clinical and non-clinical skills simultaneously, and the use of simulation in mental health is an ideal method for addressing gaps in knowledge and skills relating to communication with patients, which could directly translate to an improvement in patient care.


Assuntos
Competência Clínica , Comunicação , Relações Médico-Paciente , Psiquiatria/educação , Treinamento por Simulação , Competência Clínica/normas , Humanos , Treinamento por Simulação/métodos , Treinamento por Simulação/normas
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