[Life quality parameters in prenosologic evaluation of health state in residents of protective measures area near objects of storage and destruction of chemical weapons].

The article presents results of life quality assessment and subjective evaluation data on health state, used for prenosologic evaluation of health state in residents of protective measures area near objects of storage and destruction of chemical weapons. Considering specific features of residence near potentially dangerous objects, the authors conducted qualitative evaluation of satisfaction with various life facets, with taking into account the objects specificity, established correlation between life quality and self-evaluation of health with factors influencing public health state.

[Managerial, scientific, and practical measures for health protection of the population living and working in the protective actions zone of chemical weapons storage and destruction facilities].

The results of health assessment of the population living and working in the protective actions zone by the evidence obtained during general and special meadical examinations are summarized.

[The morphology of the micro-capsulated polyacrylic acid-based formulation of measles vaccine].

The morphology and virus localization were studied in the microcapsulated measles vaccine formulation involving polyacrylic acid (PAA) copolymers as a matrix. Transmission electron microscopy and phosphotungsic staining at a pH value of 2 to 7 showed that the morphology of microparticles was related to the value of pH and to the concentration of a polymer in the matrix. In the neutral medium, the microcapsules had the sizes of 0.5 to 10 microm, which were optimal for transport through the intestinal wall when immunization was orally used. Immunocytochemistry revealed measles virus antigen within the microparticles. The specific activity of the microcapsulated formulation of measles virus was as high as 3.36 and 4.31 lg of TCD50/0.5 ml for the samples containing 1 and 0.1% polymer, respectively. The findings suggest that the microparticles of the vaccine contain live measles virus.

[Tolerance of functional and exercise tests during 1-year antiorthostatic hypokinesia]. / Perenosimos't obsleduemymi funktsiona'lno-nagruzochnykh prob v usloviiakh godovoi antiortostaticheskoi gipokinezii.

During 370 days 9 healthy young volunteers were exposed to antiorthostatic hypokinesia. Group A consisting of 4 subjects performed exercises similar to those regularly made by Mir crewmembers and Group B consisting of 5 subjects did not exercise for 120 days and then performed experimental exercise regimens. It was demonstrated that the health status of men long exposed to head-down tilting can be controlled with the aid of various countermeasures. As a result of the exposure, orthostatic and exercise tolerance diminished. In view of the fact that the changes observed were more pronounced in the Group B subjects, it can be concluded that the countermeasures used were more effective in Group A subjects.